Diabetic neuropathy

The prognosis of people with DN depends partly on how well their diabetes is managed. Improvement in blood glucose control may slow the progression of neuropathy, but recovery may be very slow. Foot ulceration and Charcot joints are serious complications of peripheral neuropathy.

There is evidence from observational studies that autonomic neuropathy is associated with increased mortality. This may be partly due to various other complicating factors. However, people with impaired heart rate variability (cardiovascular autonomic neuropathy) have an increased risk of silent myocardial infarction and death. Symptoms associated with the rarer presentations of cranial neuropathy, mononeuropathies, truncal mononeuropathy, and diabetic amyotrophy tend to gradually improve with time.