Hypopituitarism

Recovery of baseline pituitary function is unlikely if pituitary or hypothalamic tissue has been destroyed by radiation, surgery (total hypophysectomy), or hemorrhage. In the majority of patients it is expected that lifelong hormone replacement therapy will be required.

Patients need regular close long-term follow-up with an endocrinologist to monitor hormone replacement, response to therapy, and management of the underlying etiology of hypopituitarism.