Prognosis

Without urgent pericardial drainage patients will progress to cardiovascular collapse and death.

Several studies have retrospectively examined predictors of survival after tamponade. In-hospital mortality rates have been most closely associated with the causative disease: acute myocardial infarction (70% to 100%), aortic dissection (65%), bleeding/anticoagulation (40%), malignancy (16%), iatrogenic (10%), infectious/inflammatory (8%).[10]​[20]​​ 

Malignancy-related cardiac tamponade has a poor prognosis with around 80% mortality at 12 months.[58]

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