Case history
Case history
A 23-year-old man presents with a history of recurrent erythematous lesions over the extremities with each outbreak of herpes labialis. The episodes have become more frequent, and each recurrence is more severe with time. He was prescribed oral valacyclovir 3 weeks previously, to be taken at the first sign of an oral herpes simplex virus outbreak. On examination he has target lesions over the extremities and a mild cold sore over his upper lip.
Other presentations
Mucosal lesions of the mouth (60% to 70%), nose, and genitalia may occur. Lesions can occasionally be associated with systemic lupus erythematosus (Rowell syndrome). Although rare, ocular manifestations are more likely to occur with EM major. Prodromal abdominal cramping and symptoms of upper respiratory infection can occur. Rare reports indicate that patients with HIV or cancer may present with EM.[6][7][8]
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