Polyarteritis nodosa

Hepatitis B virus (HBV) screening

There are no specific screening recommendations for PAN. Screening for HBV as a method of detecting or preventing PAN has no evidence base, and it is not known if early recognition of HBV will have any impact.

In the US, the Center for Disease Control and Prevention recommends that all adults ages 18 years and older are screened at least once in their lifetime using a triple panel test for HBV, and that people at increased risk are screened periodically:[30]Conners EE, Panagiotakopoulos L, Hofmeister MG, et al. Screening and testing for hepatitis B virus infection: CDC recommendations - United States, 2023. MMWR Recomm Rep 2023;72(No. RR-1):1–25. https://www.cdc.gov/mmwr/volumes/72/rr/rr7201a1.htm?s_cid=rr7201a1_w

• People with a history of sexually transmitted infections or multiple sex partners

• People with hepatitis C infection or a history of hepatitis C virus infection

• People incarcerated or formerly incarcerated in a jail, prison, or other detention setting

• Infants born to hepatitis B surface antigen (HBsAg)-positive people

• People born in areas with HBV infection prevalence of ≥2%

• US born people not vaccinated as infants whose parents were born in regions with HBsAg prevalence of >8%

• People who inject drugs or have a history of shot drug use

• People with HIV infection

• Men who have sex with men

• Household contact or former household contacts of people with known HBV infection

• Needle-sharing or sexual contacts of people with known HBV infection

• People on maintenance dialysis, including in-center or home hemodialysis and peritoneal dialysis

• People with elevated liver enzymes.