Morphological Uterus Sonographic Assessment (MUSA) features of adenomyosis[61]Van den Bosch T, Dueholm M, Leone FP, et al. Terms, definitions and measurements to describe sonographic features of myometrium and uterine masses: a consensus opinion from the Morphological Uterus Sonographic Assessment (MUSA) group. Ultrasound Obstet Gynecol. 2015 Sep;46(3):284-98.
https://obgyn.onlinelibrary.wiley.com/doi/10.1002/uog.14806
http://www.ncbi.nlm.nih.gov/pubmed/25652685?tool=bestpractice.com
[62]Harmsen MJ, Van den Bosch T, de Leeuw RA, et al. Consensus on revised definitions of Morphological Uterus Sonographic Assessment (MUSA) features of adenomyosis: results of modified Delphi procedure. Ultrasound Obstet Gynecol. 2022 Jul;60(1):118-31.
https://obgyn.onlinelibrary.wiley.com/doi/10.1002/uog.24786
http://www.ncbi.nlm.nih.gov/pubmed/34587658?tool=bestpractice.com
The definitive diagnosis of adenomyosis relies on histopathologic examination, but recent interest has shifted toward using transvaginal ultrasound (TVUS) or magnetic resonance imaging (MRI) to make an imaging-supported diagnosis.
The TVUS diagnostic criteria proposed by the MUSA group are now internationally accepted. The MUSA criteria are based on eight features of adenomyosis that can be detected using two-dimensional (2D) TVUS, supplemented by three-dimensional (3D) TVUS to enhance the identification and evaluation of the junctional zone.[61]Van den Bosch T, Dueholm M, Leone FP, et al. Terms, definitions and measurements to describe sonographic features of myometrium and uterine masses: a consensus opinion from the Morphological Uterus Sonographic Assessment (MUSA) group. Ultrasound Obstet Gynecol. 2015 Sep;46(3):284-98.
https://obgyn.onlinelibrary.wiley.com/doi/10.1002/uog.14806
http://www.ncbi.nlm.nih.gov/pubmed/25652685?tool=bestpractice.com
The criteria were subsequently divided into direct and indirect features of adenomyosis.[62]Harmsen MJ, Van den Bosch T, de Leeuw RA, et al. Consensus on revised definitions of Morphological Uterus Sonographic Assessment (MUSA) features of adenomyosis: results of modified Delphi procedure. Ultrasound Obstet Gynecol. 2022 Jul;60(1):118-31.
https://obgyn.onlinelibrary.wiley.com/doi/10.1002/uog.24786
http://www.ncbi.nlm.nih.gov/pubmed/34587658?tool=bestpractice.com
The direct features of adenomyosis are: the presence of cysts within the myometrium; hyperechogenic islands; and echogenic subendometrial lines or buds, which indicate the existence of ectopic endometrial glands and stroma beyond the subendometrial layer.[62]Harmsen MJ, Van den Bosch T, de Leeuw RA, et al. Consensus on revised definitions of Morphological Uterus Sonographic Assessment (MUSA) features of adenomyosis: results of modified Delphi procedure. Ultrasound Obstet Gynecol. 2022 Jul;60(1):118-31.
https://obgyn.onlinelibrary.wiley.com/doi/10.1002/uog.24786
http://www.ncbi.nlm.nih.gov/pubmed/34587658?tool=bestpractice.com
The indirect features are: a globular uterus; asymmetrical myometrial thickening; fan-shaped shadowing; translesional vascularity; an irregular or interrupted junctional zone.[62]Harmsen MJ, Van den Bosch T, de Leeuw RA, et al. Consensus on revised definitions of Morphological Uterus Sonographic Assessment (MUSA) features of adenomyosis: results of modified Delphi procedure. Ultrasound Obstet Gynecol. 2022 Jul;60(1):118-31.
https://obgyn.onlinelibrary.wiley.com/doi/10.1002/uog.24786
http://www.ncbi.nlm.nih.gov/pubmed/34587658?tool=bestpractice.com
It is important to note that in the absence of direct features, the presence of indirect features alone is not conclusive evidence for the presence of adenomyosis.[62]Harmsen MJ, Van den Bosch T, de Leeuw RA, et al. Consensus on revised definitions of Morphological Uterus Sonographic Assessment (MUSA) features of adenomyosis: results of modified Delphi procedure. Ultrasound Obstet Gynecol. 2022 Jul;60(1):118-31.
https://obgyn.onlinelibrary.wiley.com/doi/10.1002/uog.24786
http://www.ncbi.nlm.nih.gov/pubmed/34587658?tool=bestpractice.com