History and exam

Key diagnostic factors

common

acute, severe flank pain

Classical renal colic is described as severe, acute flank pain that radiates to the ipsilateral groin. However, cases may have no radiation and some stones are asymptomatic.

Other diagnostic factors

common

previous episodes of nephrolithiasis

More than 50% of patients with renal stones will have another episode within 10 years.[66][67]

nausea and vomiting

Commonly associated with acute episode.

urinary frequency/urgency

As stones pass and get lodged in the distal ureter or intramural tunnel, this can lead to bladder irritation manifested as urinary frequency or urgency.

hematuria

Microscopic hematuria is present on urinalysis in up to 84% to 90% of cases of nephrolithiasis.​[49][51]​​ Rarely, macroscopic hematuria can be present.

testicular pain

As stones pass through the ureter, flank pain can radiate toward the groin and testicle, leading to testicular pain.

obesity

Increased incidence of renal stones is correlated with increased body mass index (BMI) for both sexes.

uncommon

family history of nephrolithiasis

May be positive for nephrolithiasis in first-degree relatives. If so, this could suggest an underlying metabolic abnormality.

precipitant medications

Potential medications that can play a role in formation of renal stones include antacids, carbonic anhydrase inhibitors, sodium- and calcium-containing medications, vitamins C and D, and protease inhibitors.[38]

groin pain

As stones pass through the ureter, flank pain can radiate toward the groin.

fever

If also associated with urinary obstruction, urgent decompression is needed. May be a sign of struvite stones, which most commonly occur in association with a urinary infection.

tachycardia

May indicate urosepsis.

hypotension

May indicate urosepsis.

costovertebral angle and ipsilateral flank tenderness

May be pronounced in acute renal colic.

Use of this content is subject to our disclaimer