Pancreatic cancer is a disease with a poor prognosis. It accounts for 3.3% of new cancer diagnoses in the US, but it is the third most common cause of cancer-related death.[8]National Institutes of Health; National Cancer Institute. Cancer stat facts: pancreatic cancer. 2024 [internet publication].
https://seer.cancer.gov/statfacts/html/pancreas.html
In 2024, it is estimated there will be 66,440 new cases of pancreatic cancer and 51,750 deaths in the US.[9]Siegel RL, Giaquinto AN, Jemal A. Cancer statistics, 2024. CA Cancer J Clin. 2024 Jan-Feb;74(1):12-49.
https://acsjournals.onlinelibrary.wiley.com/doi/10.3322/caac.21820
http://www.ncbi.nlm.nih.gov/pubmed/38230766?tool=bestpractice.com
Between 2018 and 2021, the median age at diagnosis of pancreatic cancer was 70 years, and between 2018 and 2022, the median age at death was 72 years.[8]National Institutes of Health; National Cancer Institute. Cancer stat facts: pancreatic cancer. 2024 [internet publication].
https://seer.cancer.gov/statfacts/html/pancreas.html
The lifetime risk of developing pancreatic cancer was approximately 1.7%. According to data from 2014 to 2020, the 5-year survival rate is 12.8%.[8]National Institutes of Health; National Cancer Institute. Cancer stat facts: pancreatic cancer. 2024 [internet publication].
https://seer.cancer.gov/statfacts/html/pancreas.html
In one European systematic review, the age-standardized incidence of pancreatic cancer was 7.6 in 100,000 people per year in men and 4.9 in 100,000 people per year in women. Overall median survival from diagnosis was 4.6 months.[10]Carrato A, Falcone A, Ducreux M, et al. A systematic review of the burden of pancreatic cancer in Europe: real-world impact on survival, quality of life and costs. J Gastrointest Cancer. 2015 Sep;46(3):201-11.
https://www.doi.org/10.1007/s12029-015-9724-1
http://www.ncbi.nlm.nih.gov/pubmed/25972062?tool=bestpractice.com
Around 45,687 men and 45,225 women in Europe and around 5322 men and 5053 women in the UK may die from pancreatic cancer in 2024.[11]Santucci C, Mignozzi S, Malvezzi M, et al. European cancer mortality predictions for the year 2024 with focus on colorectal cancer. Ann Oncol. 2024 Mar;35(3):308-16.
https://www.annalsofoncology.org/article/S0923-7534(23)05110-4/fulltext
http://www.ncbi.nlm.nih.gov/pubmed/38286716?tool=bestpractice.com