The prevalence of colonic diverticular disease increases with age, affecting around 25% of adults ages 40-49 years, approximately 35% at 50-59 years of age, approximately 50% in those ages 60-69 years, 65% in those ages 70-79 years, and around 70% in adults over 80 years of age.[11]Peery AF, Keku TO, Galanko JA, et al. Sex and race disparities in diverticulosis prevalence. Clin Gastroenterol Hepatol. 2020 Aug;18(9):1980-6.
https://www.cghjournal.org/article/S1542-3565(19)31166-8/fulltext
http://www.ncbi.nlm.nih.gov/pubmed/31634580?tool=bestpractice.com
In addition, there has been a rising incidence of diverticular disease among patients younger than 45 years old.[12]Jacqueline D, Lince K, DeMario VK, et al. Diverticulitis in the under-40 population. Cureus. 2024 Mar;16(3):e56190.
https://www.cureus.com/articles/155859-diverticulitis-in-the-under-40-population#!
http://www.ncbi.nlm.nih.gov/pubmed/38618478?tool=bestpractice.com
In younger patients below the age of 80 there is a slightly lower prevalence of diverticulosis in women than in men; over age 80 there is no sex difference in risk.[9]Imaeda H, Hibi T. The burden of diverticular disease and its complications: west versus east. Inflamm Intest Dis. 2018 Dec;3(2):61-8.
https://pmc.ncbi.nlm.nih.gov/articles/PMC6361582
http://www.ncbi.nlm.nih.gov/pubmed/30733949?tool=bestpractice.com
[11]Peery AF, Keku TO, Galanko JA, et al. Sex and race disparities in diverticulosis prevalence. Clin Gastroenterol Hepatol. 2020 Aug;18(9):1980-6.
https://www.cghjournal.org/article/S1542-3565(19)31166-8/fulltext
http://www.ncbi.nlm.nih.gov/pubmed/31634580?tool=bestpractice.com
Changes in race-related incidence of diverticular disease have also been observed. One systematic review found a threefold increase in the prevalence rate of colonic diverticulosis in Africa.[13]Ray-Offor E, Egboh SM, Ijah RFOA, et al. Colonic diverticulosis at colonoscopy in Africa: a systematic review and meta-analysis of pooled estimates. Dig Surg. 2024;41(2):63-78.
http://www.ncbi.nlm.nih.gov/pubmed/38377978?tool=bestpractice.com
In the US from 2000 to 2007 the incidence of colonic diverticulitis was 209 adults per 100,000 person-years.[2]Peery AF. Management of colonic diverticulitis. BMJ. 2021 Mar 24;372:n72.
http://www.ncbi.nlm.nih.gov/pubmed/33762260?tool=bestpractice.com
In a study of US patients (inpatient and outpatient) with diverticulitis, the incidence of diverticulitis was found to have increased by 50% from 2000-07 compared with 1990-99.[2]Peery AF. Management of colonic diverticulitis. BMJ. 2021 Mar 24;372:n72.
http://www.ncbi.nlm.nih.gov/pubmed/33762260?tool=bestpractice.com
This trend was similar in men and women, and was most significant in adults ages 30-49 years.[2]Peery AF. Management of colonic diverticulitis. BMJ. 2021 Mar 24;372:n72.
http://www.ncbi.nlm.nih.gov/pubmed/33762260?tool=bestpractice.com
Hospital admissions for diverticulitis have also increased over this time, but there was no observed increase in the incidence of complicated diverticulitis.[2]Peery AF. Management of colonic diverticulitis. BMJ. 2021 Mar 24;372:n72.
http://www.ncbi.nlm.nih.gov/pubmed/33762260?tool=bestpractice.com