Monitoring

GAD is a chronic, fluctuating, remitting and relapsing disorder that generally requires long-term treatment.[52] After an acute trial of pharmacotherapy over 12 weeks, effective treatment should be continued for at least 12 months. Patients should be monitored throughout this period to ensure continued benefit. A trial taper from the medication may be made at that time, with treatment reinstated if relapse occurs.[40]​ Several medications shown to be effective for short-term treatment have also been shown to be effective for relapse prevention.[221][222]

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