Patient discussions

Patient education about their diagnosis, medication, and self-management fosters insight, adherence, and improved health-related quality of life.[61][101]

Any medication changes should be done under the supervision of a physician. Patients who experience adverse effects should discuss the issues with their physician and appropriate alterations should be made. Stopping medication abruptly can be dangerous because the symptoms are likely to return, which can result in disability and danger to self and others. Patients who begin to experience command auditory hallucinations, suicidal thoughts, thoughts of harming others, or other severe symptoms should be instructed to call their doctor, call the emergency call number (911 in the US), or go to the nearest emergency department. Additionally, drugs and alcohol should be avoided, because these substances can worsen symptoms, cause symptoms to reappear, and increase drowsiness and sedation.

Peer-led advocacy groups, such as the National Alliance on Mental Illness (NAMI) in the US, can be helpful for patients and their families by providing practical and emotional support, as well as being sources of information about the condition itself, available resources (e.g., groups, volunteering opportunities, job training, and employment), economic and legal matters, and other information. National Alliance on Mental Illness Opens in new window

For females of childbearing age, valproate treatment should not be started unless alternative treatments are not suitable; females of childbearing age must follow a pregnancy prevention program while on treatment with valproate medicines. An example of one such program was launched in 2018 by the European Medicines Agency, for use across the EU, and includes the following:[52]

  • An assessment of patient’s potential for becoming pregnant

  • Pregnancy tests before starting and during treatment as needed

  • Counseling about the risks of valproate treatment and the need for effective contraception throughout treatment

  • A review of ongoing treatment by a specialist at least annually

  • A risk acknowledgement form that patients and prescribers will go through at each such annual review to confirm that appropriate advice has been given and understood.

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