Prognosis

Recurrences are common but often occur in clusters.[86] In one meta-analysis, 36% of patients in randomized and cohort studies fainted during the study follow-up period (median follow-up 2 years).[87]

The estimated 1-year mortality rate after syncope (all causes) is 8.4%.[88] The mortality risk is mainly related to cardiovascular causes.[25] Patients with NMRS typically have a better prognosis than patients with cardiac syncope, but injury is a concern due to recurrent falls, especially in older people.[13] In one meta-analysis, injury due to vasovagal syncope occurred in one third of patients; the rate of major injury was 13.9%.[89]

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