Small cell lung cancer

Veterans Administration Lung Cancer Study Group: small cell lung cancer[37]Micke P, Faldum A, Metz T, et al. Staging small cell lung cancer: Veterans Administration Lung Study Group versus International Association for the Study of Lung Cancer--what limits limited disease? Lung Cancer. 2002 Sep;37(3):271-6. http://www.ncbi.nlm.nih.gov/pubmed/12234695?tool=bestpractice.com [38]Kalemkerian GP, Gadgeel SM. Modern staging of small cell lung cancer. J Natl Compr Canc Netw. 2013 Jan 1;11(1):99-104. https://jnccn.org/view/journals/jnccn/11/1/article-p99.xml http://www.ncbi.nlm.nih.gov/pubmed/23307985?tool=bestpractice.com ​​

Older and more common staging system for small cell lung cancer.

• Limited stage: disease confined to the ipsilateral hemithorax, which can be safely encompassed within a tolerable radiation field.

• Extensive stage: all other disease, including metastatic disease and malignant pleural/pericardial effusions.

American Joint Committee on Cancer staging (8th edition, 2017): small cell lung cancer[39]Amin MB, Edge SB, Greene FL, et al, eds. AJCC Cancer Staging Manual. 8th ed. New York: Springer; 2017.

The American Joint Committee on Cancer staging system describes the extent of disease based on the following anatomic factors: size and extent of the primary tumor (T); regional lymph node involvement (N); and presence or absence of distant metastases (M).[39]Amin MB, Edge SB, Greene FL, et al, eds. AJCC Cancer Staging Manual. 8th ed. New York: Springer; 2017.