Leptospirosis

Centers for Disease Control and Prevention (CDC): leptospirosis (Leptospira interrogans) case definition[60]Centers for Disease Control and Prevention: National Notifiable Diseases Surveillance System (NNDSS). Leptospirosis (Leptospira interrogans) 2013 case definition. Apr 2021 [internet publication]. https://ndc.services.cdc.gov/case-definitions/leptospirosis-2013

Clinical criteria include history of fever within the past 2 weeks and at least two of the following:

• Myalgia

• Headache

• Jaundice

• Conjunctival suffusion without purulent discharge

• Rash (i.e., maculopapular or petechial).

Or at least one of the following:

• Aseptic meningitis

• Gastrointestinal symptoms (e.g., abdominal pain, nausea, vomiting, diarrhoea)

• Pulmonary complications (e.g., cough, breathlessness, haemoptysis)

• Cardiac arrhythmias, ECG abnormalities

• Renal insufficiency (e.g., anuria, oliguria)

• Haemorrhage (e.g., intestinal, pulmonary, haematuria, haematemesis)

• Jaundice with acute renal failure.

The full leptospirosis case definition, including laboratory criteria for diagnosis and epidemiological linkage, is provided by the CDC: CDC: leptospirosis (Leptospira interrogans) 2013 case definition Opens in new window