Monitoring

Reticulocytosis can be assessed at the end of the first week of therapy.[40] It is important to determine completeness of response after 8 weeks of therapy, when blood counts should have normalised.[70][71]

Homocysteine levels fall within a few days of therapy and may be used to assess treatment response.

Inadequate response indicates a co-existing cause of anaemia, such as iron deficiency or vitamin B12 (cobalamin) deficiency.

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