Trials involving boys suggest that circumcision is preventative.[31]Singh-Grewal D, Macdessi J, Craig J. Circumcision for the prevention of urinary tract infection in boys: a systematic review of randomised trials and observational studies. Arch Dis Child. 2005 Aug;90(8):853-8.
https://adc.bmj.com/content/90/8/853.long
http://www.ncbi.nlm.nih.gov/pubmed/15890696?tool=bestpractice.com
However, no clear recommendations exist for adult males. Silver- or antibiotic-coated catheters decrease catheter-associated bacteriuria but have not conclusively been shown to prevent urinary tract infection (UTI); therefore, removal or avoidance of the catheter offers the best prevention.[27]Huang W, Wann S, Lin S, et al. Catheter-associated urinary tract infections in intensive care units can be reduced by prompting physicians to remove unnecessary catheters. Infect Control Hosp Epidemiol. 2004 Nov;25(11):974-8.
http://www.ncbi.nlm.nih.gov/pubmed/15566033?tool=bestpractice.com
[32]Johnson JR, Kuskowski MA, Wilt TJ. Systematic review: antimicrobial urinary catheters to prevent catheter-associated urinary tract infection in hospitalized patients. Ann Intern Med. 2006 Jan 17;144(2):116-26.
http://annals.org/aim/article/719502/systematic-review-antimicrobial-urinary-catheters-prevent-catheter-associated-urinary-tract
http://www.ncbi.nlm.nih.gov/pubmed/16418411?tool=bestpractice.com
[33]Lam TB, Omar M, Fisher E, et al. Types of indwelling urethral catheters for short-term catheterisation in hospitalised adults. Cochrane Database Syst Rev. 2014 Sep 23;(9):CD004013.
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD004013.pub4/full
http://www.ncbi.nlm.nih.gov/pubmed/25248140?tool=bestpractice.com
[34]Drekonja DM, Kuskowski MA, Wilt TJ, et al. Antimicrobial urinary catheters: a systematic review. Exp Rev Med Devices. 2008 Jul;5(4):495-506.
http://www.ncbi.nlm.nih.gov/pubmed/18573048?tool=bestpractice.com
[35]Tenke P, Kovacs B, Bjerklund Johansen TE, et al. European and Asian guidelines on management and prevention of catheter-associated urinary tract infections. Int J Antimicrob Agents. 2008 Feb;31(suppl 1):S68-78.
http://www.ncbi.nlm.nih.gov/pubmed/18006279?tool=bestpractice.com
[36]Stensballe J, Tvede M, Looms D, et al. Infection risk with nitrofurazone-impregnated urinary catheters in trauma patients: a randomized trial. Ann Intern Med. 2007 Sep 4;147(5):285-93.
http://www.ncbi.nlm.nih.gov/pubmed/17785483?tool=bestpractice.com
[37]Pickard R, Lam T, MacLennan G, et al. Antimicrobial catheters for reduction of symptomatic urinary tract infection in adults requiring short-term catheterisation in hospital: a multicentre randomised controlled trial. Lancet. 2012 Dec 1;380(9857):1927-35.
http://www.ncbi.nlm.nih.gov/pubmed/23134837?tool=bestpractice.com
The quality and applicability of evidence regarding prophylaxis for use of several pharmacological (e.g., methenamine hippurate) and non-pharmaceutical treatment strategies (e.g., encouraging cranberry juice intake) in clinical practice for different patient groups is debatable, as there are significant gaps in understanding for particular subgroups of men with UTI. Trial of these therapies should never preclude investigation for structural abnormality in the male urinary tract.[38]Jepson RG, Williams G, Craig JC. Cranberries for preventing urinary tract infections. Cochrane Database Syst Rev. 2012 Oct 17;(10):CD001321.
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD001321.pub5/full
http://www.ncbi.nlm.nih.gov/pubmed/23076891?tool=bestpractice.com
[39]Jepson RG, Craig JC. A systematic review of the evidence for cranberries and blueberries in UTI prevention. Mol Nutr Food Res. 2007 Jun;51(6):738-45.
http://www.ncbi.nlm.nih.gov/pubmed/17492798?tool=bestpractice.com
[40]Lee BS, Bhuta T, Simpson JM, et al. Methenamine hippurate for preventing urinary tract infections. Cochrane Database Syst Rev. 2012 Oct 17;(10):CD003265.
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD003265.pub3/full
http://www.ncbi.nlm.nih.gov/pubmed/23076896?tool=bestpractice.com
[41]Cruz F, Dambros M, Naber KG, et al. Recurrent urinary tract infections: Uro-Vaxom, a new alternative. Eur Urol Suppl. 2009;8:762-8.[42]Naber KG, Cho YH, Matsumoto T, et al. Immunoactive prophylaxis of recurrent urinary tract infections: a meta-analysis. Int J Antimicrob Agents. 2009 Feb;33(2):111-9.
http://www.ncbi.nlm.nih.gov/pubmed/18963856?tool=bestpractice.com