Epidemiology

Prevalence estimates for CVI vary widely, depending on geographical region and diagnostic criteria.[3][4][5][6]​​​​​​[7][8]​​​ In one systematic review, the estimated pooled prevalence was 8% for class C3 (oedema), 4% for class C4 (skin changes secondary to CVI), 1% for class C5 (healed venous ulcer), and 0.42% for class C6 (active venous ulcer).[4]

Common risk factors for chronic venous disease, and CVI, are increasing age, female sex, obesity, family history, and occupations with prolonged standing.

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