Epidemiology

Trace or mild pulmonary regurgitation is commonly detected on echocardiography in patients without structural heart disease. Non-severe pulmonary regurgitation is usually asymptomatic and is most commonly secondary to pulmonary hypertension. Severe isolated pulmonary regurgitation is usually a manifestation of prior surgical repair or balloon pulmonary valvuloplasty, so patients may present later in life.[2]​ However, even with severe isolated pulmonary regurgitation, only 40% of the patients present with symptoms, so the true incidence and prevalence is unknown. There is no specific sex or ethnicity predominance; however, it is commonly associated with younger age.[3]

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