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Last reviewed: 16 Mar 2025
Last updated: 06 Mar 2025

Summary

Definition

History and exam

Key diagnostic factors

  • presence of risk factors
  • recurrent episodes of binge eating
  • recurrent inappropriate compensatory behaviour
  • eating disturbance not exclusively during periods of anorexia nervosa
  • depression and low self-esteem
  • concern about weight and body shape
  • dental erosion
  • parotid hypertrophy
  • Russell's sign
  • arrhythmia

Other diagnostic factors

  • age 20 to 35 years
  • menstrual irregularity
  • drug-seeking behaviour
  • deliberate misuse of insulin
  • self-injurious behaviour
  • gastrointestinal symptoms
  • history of dieting
  • marked fluctuations in weight
  • shoplifting behaviour
  • use of ipecac
  • needle marks on skin
  • vomiting in pregnancy

Risk factors

  • female sex
  • personality disorder
  • body-image dissatisfaction
  • history of sexual abuse
  • impulsivity
  • family history of alcoholism
  • family history of depression
  • family history of eating disorder
  • childhood overweight or obesity
  • exposure to media pressure
  • early onset of puberty
  • urbanisation
  • family history of obesity
  • participation in elite-level sports

Diagnostic investigations

1st investigations to order

  • serum electrolytes
  • serum creatinine
  • serum magnesium
  • urine pregnancy test
  • serum LFTs
  • serum creatine kinase (CK)
  • FBC
  • urinalysis

Investigations to consider

  • ECG
  • serum ferritin
  • serum B12
  • serum red blood cell folate
  • dual-energy x-ray absorptiometry scan for bone density

Treatment algorithm

Contributors

Authors

Debra L. Safer, MD

Associate Professor

Co-Director of Stanford Eating and Weight Disorders Program

Stanford University School of Medicine

Department of Psychiatry & Behavioral Sciences

Stanford

CA

Disclosures

DLS is an author of a reference cited in this topic, and receives royalties from Guilford Press for books on adapting dialectical behaviour therapy for eating disorders.

Acknowledgements

Dr Debra L. Safer would like to gratefully acknowledge Dr David C.W. Lau and Dr C. Laird Birmingham, the previous contributors to this topic.

Disclosures

DCWL declares that he has no competing interests. CLB is an author of several references cited in this topic.

Peer reviewers

Mimi Israel, MD, FRCPC

Chair of Psychiatry

McGill University

Quebec

Canada

Disclosures

MI declares that she has no competing interests.

Joel Yager, MD

Professor

Department of Psychiatry

University of New Mexico School of Medicine

Albuquerque

NM

Disclosures

JY is an author of a reference cited in this topic.

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