Complications

Complication
Timeframe
Likelihood
variable
low

Metabolic syndrome, breast cancer, cardiovascular disease: the risks are theoretical based on the known increased risk of these conditions with high endogenous testosterone levels.[157][161] Testosterone should be discontinued.

Hirsutism, acne: known effects of testosterone.[158] If these effects are more than what was experienced pre-menopause from endogenous androgens, then dose should be reduced or discontinued.

Clitoromegaly, voice change: not expected with doses that approximate premenopausal physiological testosterone concentrations.[158] Testosterone should be discontinued.

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