References
Key articles
Lavonas EJ, Akpunonu PD, Arens AM, et al. 2023 American Heart Association focused update on the management of patients with cardiac arrest or life-threatening toxicity due to poisoning: an update to the American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation. 2023 Oct 17;148(16):e149-84.Full text Abstract
Royal College of Emergency Medicine. Management of suspected internal drug trafficker (SIDT). Dec 2020 [internet publication].Full text
Panchal AR, Bartos JA, Cabañas JG, et al. Part 3: adult basic and advanced life support: 2020 American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation. 2020 Oct 20;142(16_suppl_2):S366-468.Full text
Smollin CG, Hoffman RS. Chapter 75: Cocaine. In: Nelson LS, Howland MA, Lewin NA, et al, eds. Goldfrank's toxicologic emergencies, 11th ed. New York, NY: McGraw-Hill Education; 2019.
Reference articles
1. United Nations Office on Drugs and Crime. World drug report 2023. 2023 [internet publication].Full text
2. European Monitoring Centre for Drugs and Drug Addiction. Statistical Bulletin 2021 - prevalence of drug use. 2021 [internet publication].Full text
3. Office for National Statistics (UK). Drug misuse: findings from the 2018/2019 crime survey for England and Wales. Sep 2019 [internet publication].Full text
4. Substance Abuse and Mental Health Services Administration (SAMHSA), US Department of Health and Human Services (HHS). Key substance use and mental health indicators in the United States: results from the 2019 National Survey on Drug Use and Health. Sep 2020 [internet publication].Full text
5. Centers for Disease Control and Prevention. Trends in the prevalence of marijuana, cocaine, and other illegal drug use national Youth Risk Behavior Survey: 1991-2019. Aug 2020 [internet publication].Full text
6. Kaye S, Darke S. Non-fatal cocaine overdose among injecting and non-injecting cocaine users in Sydney, Australia. Addiction. 2004 Oct;99(10):1315-22. Abstract
7. Curtin SC, Tejada-Vera B, Warmer M. Drug overdose deaths among adolescents aged 15-19 in the United States: 1999-2015. NCHS Data Brief. 2017 Aug;(282):1-8.Full text Abstract
8. Spencer MR, Miniño AM, Garnett MF. Co-involvement of opioids in drug overdose deaths involving cocaine and psychostimulants, 2011-2021. NCHS Data Brief. 2023 Jul;(474):1-8.Full text Abstract
9. Marzuk PM, Tardiff K, Leon AC, et al. Ambient temperature and mortality from unintentional cocaine overdose. JAMA. 1998 Jun 10;279(22):1795-800. Abstract
10. Lai MW, Klein-Schwartz W, Rodgers GC, et al. 2005 annual report of the American Association of Poison Control Centers' national poisoning and exposure database. Clin Toxicol (Phila). 2006;44(6-7):803-932. Abstract
11. Bernstein KT, Bucciarelli A, Piper TM, et al. Cocaine and opiate-related fatal overdose in New York City 1990-2000. BMC Public Health. 2007 Mar 9;7:31.Full text Abstract
12. Black JC, Bau GE, Iwanicki JL, et al. Association of medical stimulants with mortality in the US from 2010 to 2017. JAMA Intern Med. 2021 May 1;181(5):707-9. Abstract
13. Wood DM, Dargan PI, Hoffman RS. Management of cocaine-induced cardiac arrhythmias due to cardiac ion channel dysfunction. Clin Toxicol (Phila). 2009 Jan;47(1):14-23. Abstract
14. Temesy-Armos PN, Fraker TD, Brewster PS, et al. The effects of cocaine on cardiac electrophysiology in conscious dogs. J Cardiovasc Pharmacol. 1992 Jun;19(6):883-91. Abstract
15. Ramirez FD, Femenía F, Simpson CS, et al. Electrocardiographic findings associated with cocaine use in humans: a systematic review. Expert Rev Cardiovasc Ther. 2012 Jan;10(1):105-27. Abstract
16. Leshner A. Molecular mechanisms of cocaine addiction. N Engl J Med. 1996 Jul 11;335(2):128-9.
17. Volkow ND, Wang GJ, Fischman MW, et al. Relationship between subjective effects of cocaine and dopamine transporter occupancy. Nature. 1997 Apr 24;386(6627):827-30. Abstract
18. Lange RA, Cigarroa RG, Yancy CW, et al. Cocaine-induced coronary artery vasoconstriction. N Engl J Med. 1989 Dec 7;321(23):1557-62. Abstract
19. Marzuk PM, Tardiff K, Leon AC, et al. Poverty and fatal accidental drug overdoses of cocaine and opiates in New York City: an ecological study. Am J Drug Alcohol Abuse. 1997 May;23(2):221-8. Abstract
20. Public Health England. Drug misuse treatment in England: evidence review of outcomes. 26 January 2017 [internet publication].Full text
21. Hoffman RS, Henry GC, Howland MA, et al. Association between life-threatening cocaine toxicity and plasma cholinesterase activity. Ann Emerg Med. 1992 Mar;21(3):247-53. Abstract
22. McCord J, Jneid H, Hollander JE, et al. Management of cocaine-associated chest pain and myocardial infarction: a scientific statement from the American Heart Association Acute Cardiac Care Committee of the Council on Clinical Cardiology. Circulation. 2008 Apr 8;117(14):1897-907.Full text
23. Lavonas EJ, Akpunonu PD, Arens AM, et al. 2023 American Heart Association focused update on the management of patients with cardiac arrest or life-threatening toxicity due to poisoning: an update to the American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation. 2023 Oct 17;148(16):e149-84.Full text Abstract
24. Zimmerman JL. Cocaine intoxication. Crit Care Clin. 2012 Oct;28(4):517-26. Abstract
25. Webb A, Angus D C, Finfer S, et al. Oxford textbook of critical care. 2nd ed. Oxford: Oxford University Press; 2016.
26. Writing Committee Members, Gulati M, Levy PD, Mukherjee D, et al. 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR guideline for the evaluation and diagnosis of chest pain: a report of the American College of Cardiology/American Heart Association joint committee on clinical practice guidelines. J Am Coll Cardiol. 2021 Nov 30;78(22):e187-285.Full text
27. Thygesen K, Alpert JS, Jaffe AS, et al. Fourth universal definition of myocardial infarction (2018). J Am Coll Cardiol. 2018 Oct 30;72(18):2231-64.Full text
28. Jordan CD, Korley FK, Stolbach AI. Self-reported cocaine use is not associated with elevations in high-sensitivity troponin I. Clin Toxicol (Phila). 2017 Jun;55(5):332-7. Abstract
29. Royal College of Emergency Medicine. Management of suspected internal drug trafficker (SIDT). Dec 2020 [internet publication].Full text
30. Mégarbane B, Oberlin M, Alvarez JC, et al. Management of pharmaceutical and recreational drug poisoning. Ann Intensive Care. 2020 Nov 23;10(1):157.Full text Abstract
31. Hollander JE, Hoffman RS, Gennis P, et al. Prospective multi-center evaluation of cocaine-associated chest pain. Acad Emerg Med. 1994 Jul-Aug;1(4):330-9.Full text Abstract
32. Levine SR, Brust JC, Futrell N, et al. Cerebrovascular complications of the use of the "crack" form of alkaloidal cocaine. N Engl J Med. 1990 Sep 13;323(11):699-704.Full text Abstract
33. Ewing JA. Detecting alcoholism: the CAGE questionnaire. JAMA. 1984 Oct 12;252(14):1905-7. Abstract
34. Seltzer ML. The Michigan alcoholism screening test: the quest for a new diagnostic instrument. Am J Psychiatry. 1971 Jun;127(12):1653-8.
35. Sawka AM, Jaeschke R, Singh RJ, et al. A comparison of biochemical tests for pheochromocytoma: measurement of fractionated plasma metanephrines compared with the combination of 24-hour urinary metanephrines and catecholamines. J Clin Endocrinol Metab. 2003 Feb;88(2):553-8.Full text Abstract
36. Richards JR, Hollander JE, Ramoska EA, et al. β-blockers, cocaine, and the unopposed α-stimulation phenomenon. J Cardiovasc Pharmacol Ther. 2017 May;22(3):239-49.Full text Abstract
37. Lott C, Truhlář A, Alfonzo A, et al. European Resuscitation Council guidelines 2021: cardiac arrest in special circumstances. Resuscitation. 2021 Apr;161:152-219.Full text Abstract
38. Stroup TS, Gray N. Management of common adverse effects of antipsychotic medications. World Psychiatry. 2018 Oct;17(3):341-56.Full text Abstract
39. Cole JB, Moore JC, Nystrom PC, et al. A prospective study of ketamine versus haloperidol for severe prehospital agitation. Clin Toxicol (Phila). 2016 Aug;54(7):556-62. Abstract
40. Panchal AR, Bartos JA, Cabañas JG, et al. Part 3: adult basic and advanced life support: 2020 American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation. 2020 Oct 20;142(16_suppl_2):S366-468.Full text
41. Smollin CG, Hoffman RS. Chapter 75: Cocaine. In: Nelson LS, Howland MA, Lewin NA, et al, eds. Goldfrank's toxicologic emergencies, 11th ed. New York, NY: McGraw-Hill Education; 2019.
42. Winecoff AP, Hariman RJ, Grawe JJ, et al. Reversal of the electrocardiographic effects of cocaine by lidocaine. Part 1: comparison with sodium bicarbonate and quinidine. Pharmacotherapy. 1994 Nov-Dec;14(6):698-703. Abstract
43. Parker RB, Perry GY, Horan LG, et al. Comparative effects of sodium bicarbonate and sodium chloride on reversing cocaine-induced changes in the electrocardiogram. J Cardiovasc Pharmacol. 1999 Dec;34(6):864-9. Abstract
44. Phillips K, Luk A, Soor GS, et al. Cocaine cardiotoxicity: A review of the pathophysiology, pathology, and treatment options . Am J Cardiovasc Drugs. 2009;9(3):177-96. Abstract
45. Shih RD, Hollander JE, Burstein JL, et al. Clinical safety of lidocaine in patients with cocaine-associated myocardial infarction. Ann Emerg Med. 1995 Dec;26(6):702-6. Abstract
46. Casa DJ, DeMartini JK, Bergeron MF, et al. National Athletic Trainers' Association position statement: exertional heat illnesses. J Athl Train. 2015 Sep;50(9):986-1000.Full text Abstract
47. Armstrong LE, Crago AE, Adams R, et al. Whole-body cooling of hyperthermic runners: comparison of two field therapies. Am J Emerg Med. 1996 Jul;14(4):355-8. Abstract
48. Jatlow P, Barash PG, Van Dyke C, et al. Cocaine and succinylcholine sensitivity: a new caution. Anesth Analg. 1979 May-Jun;58(3):235-8. Abstract
49. Catravas JD, Waters IW. Acute cocaine intoxication in the conscious dog: studies on the mechanism of lethality. J Pharmacol Exp Ther. 1981 May;217(2):350-6.
50. Nelson LS, Olsen D. Chapter 38: opioids. In: Hoffman RS, Nelson LS, Goldfrank LR, et al, eds. Goldfrank's toxicologic emergencies. 9th ed. New York, NY: McGraw-Hill; 2011.
51. Booker RJ, Smith JE, Rodger MP. Packers, pushers and stuffers--managing patients with concealed drugs in UK emergency departments: a clinical and medicolegal review. Emerg Med J. 2009 May;26(5):316-20.Full text Abstract
52. Thanacoody R, Caravati EM, Troutman B, et al. Position paper update: whole bowel irrigation for gastrointestinal decontamination of overdose patients. Clin Toxicol (Phila). 2015 Jan;53(1):5-12. Abstract
53. Traub SJ, Hoffman RS, Nelson LS. Body packing: the internal concealment of illicit drugs. N Engl J Med. 2003 Dec 25;349(26):2519-26.
54. Heesch CM, Wilhelm CR, Ristich J, et al. Cocaine activates platelets and increases the formation of circulating platelet containing microaggregates in humans. Heart. 2000 Jun;83(6):688-95.Full text Abstract
55. Darke S, Kaye S, Duflou J. Comparative cardiac pathology among deaths due to cocaine toxicity, opioid toxicity, and non-drug-related causes. Addiction. 2006 Dec;101(12):1771-7. Abstract
56. Kolodgie FD, Wilson PS, Mergner WJ, et al. Cocaine-induced increase in the permeability function of human vascular endothelial cell monolayers. Exp Mol Pathol. 1999 Jun;66(2):109-22. Abstract
57. World Health Organization. Mental Health Gap Action Programme (mhGAP) guideline for mental, neurological and substance use disorders. Nov 2023 [internet publication].Full text
58. National Institute for Health and Care Excellence. Drug misuse in over 16s: psychosocial interventions. 25 July 2007 [internet publication].Full text
59. Minozzi S, Saulle R, Amato L, et al. Psychosocial interventions for stimulant use disorder. Cochrane Database Syst Rev. 2024 Feb 15;2(2):CD011866.Full text Abstract
60. National Institute for Health and Care Excellence. Drug misuse prevention: targeted interventions. 22 February 2017 [internet publication].Full text
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