Prognosis

Most patients with MVP have an excellent prognosis similar to age- and sex-matched controls.[6] A small number will develop serious complications that include infective endocarditis, severe mitral regurgitation, and sudden cardiac death.

Patients at increased risk can be identified by clinical and echocardiographic features and will require vigilant follow-up.[25] Increased risk of developing severe mitral regurgitation is associated with male sex, age greater than 45 years, elevated BMI, hypertension, left ventricular enlargement, left ventricular dysfunction, and thickened mitral valve leaflets.[5][6][40][41][42]

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