Ovarian torsion
- Overview
- Theory
- Diagnosis
- Management
- Follow up
- Resources
Treatment algorithm
Please note that formulations/routes and doses may differ between drug names and brands, drug formularies, or locations. Treatment recommendations are specific to patient groups: see disclaimer
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surgical detorsion or salpingo-oophorectomy
Ensure the patient goes to surgery without delay where there is suspicion of ovarian torsion based on clinical signs and symptoms and/or findings on imaging, and where preserving fertility is a priority.
A delay in the timing of surgery is associated with a reduction in the possibility of ovarian salvage.[15]Kives S, Gascon S, Dubuc É, et al. No. 341 - diagnosis and management of adnexal torsion in children, adolescents, and adults. J Obstet Gynaecol Can. 2017 Feb;39(2):82-90. http://www.ncbi.nlm.nih.gov/pubmed/28241927?tool=bestpractice.com
Choice of surgical approach for detorsion, via laparoscopy versus laparotomy, depends on the clinical situation and clinical judgement.[27]Bar-On S, Mashiach R, Stockheim D, et al. Emergency laparoscopy for suspected ovarian torsion: are we too hasty to operate? Fertil Steril. 2010 Apr;93(6):2012-5. http://www.ncbi.nlm.nih.gov/pubmed/19159873?tool=bestpractice.com [58]Oelsner G, Cohen SB, Soriano D, et al. Minimal surgery for the twisted ischaemic adnexa can preserve ovarian function. Hum Reprod. 2003 Dec;18(12):2599-602. http://humrep.oxfordjournals.org/content/18/12/2599.full http://www.ncbi.nlm.nih.gov/pubmed/14645177?tool=bestpractice.com [60]Mashiach S, Bider D, Moran O, et al. Adnexal torsion of hyperstimulated ovaries in pregnancies after gonadotropin therapy. Fertil Steril. 1990 Jan;53(1):76-80. http://www.ncbi.nlm.nih.gov/pubmed/2295348?tool=bestpractice.com [70]Cohen SB, Wattiez A, Seidman DS, et al. Laparoscopy versus laparotomy for detorsion and sparing of twisted ischemic adnexa. JSLS. 2003 Oct-Dec;7(4):295-9. http://www.ncbi.nlm.nih.gov/pubmed/14626393?tool=bestpractice.com [71]Way S. Ovarian cystectomy of twisted cysts. Lancet. 1946 Jul 13;2(6411):47-8.[72]McGovern PG, Noah R, Koenigsberg R, et al. Adnexal torsion and pulmonary embolism: case report and review of the literature. Obstet Gynecol Surv. 1999 Sep;54(9):601-8. http://www.ncbi.nlm.nih.gov/pubmed/10481857?tool=bestpractice.com [73]Gorkemli H, Camus M, Clasen K. Adnexal torsion after gonadotropin ovulation induction for IVF or ICSE and its conservative treatment. Arch Gynecol Obstet. 2002 Nov;267(1):4-6. http://www.ncbi.nlm.nih.gov/pubmed/12410364?tool=bestpractice.com [74]Ben-Rafael Z, Bider D, Mashiach S. Laparoscopic unwinding of twisted ischemic hemorrhagic adnexum after in vitro fertilization. Fertil Steril. 1990 Mar;53(3):569-71. http://www.ncbi.nlm.nih.gov/pubmed/2137796?tool=bestpractice.com [75]Oelsner G, Bider D, Goldenberg M, et al. Long-term follow-up of the twisted ischemic adnexa managed by detorsion. Fertil Steril. 1993 Dec;60(6):976-9. http://www.ncbi.nlm.nih.gov/pubmed/8243702?tool=bestpractice.com If clinically appropriate, laparoscopy may be superior to laparotomy because it decreases hospital stay and postoperative pain, with reduced consumption of analgesic drugs.[56]Balasubramaniam D, Duraisamy KY, Ezhilmani M. Laparoscopic detorsion and fertility preservation in twisted ischemic adnexa - a single-center prospective study. Gynecol Minim Invasive Ther. 2020 Jan-Mar;9(1):24-8. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008646 http://www.ncbi.nlm.nih.gov/pubmed/32090009?tool=bestpractice.com
Intraoperative evaluation should be performed. Conservative management with detorsion is highly recommended regardless of the actual appearance of the ovary, which may be dusky, blue-black, or necrotic-appearing.[1]American College of Obstetricians and Gynecologists. Adnexal torsion in adolescents: ACOG committee opinion no, 783. Obstet Gynecol. 2019 Aug;134(2):e56-63. https://www.doi.org/10.1097/AOG.0000000000003373 http://www.ncbi.nlm.nih.gov/pubmed/31348225?tool=bestpractice.com [51]Wang JH, Wu DH, Jin H, et al. Predominant etiology of adnexal torsion and ovarian outcome after detorsion in premenarchal girls. Eur J Pediatr Surg. 2010 Sep;20(5):298-301. http://www.ncbi.nlm.nih.gov/pubmed/20533130?tool=bestpractice.com [52]Dasgupta R, Renaud E, Goldin AB, et al. Ovarian torsion in pediatric and adolescent patients: a systematic review. J Pediatr Surg. 2018 Jul;53(7):1387-91. http://www.ncbi.nlm.nih.gov/pubmed/29153467?tool=bestpractice.com [53]Yasa C, Dural O, Bastu E, et al. Impact of laparoscopic ovarian detorsion on ovarian reserve. J Obstet Gynaecol Res. 2017 Feb;43(2):298-302. http://www.ncbi.nlm.nih.gov/pubmed/27928855?tool=bestpractice.com [54]Geimanaite L, Trainavicius K. Ovarian torsion in children: management and outcomes. J Pediatr Surg. 2013 Sep;48(9):1946-53. http://www.ncbi.nlm.nih.gov/pubmed/24074673?tool=bestpractice.com This ensures preservation of ovarian function in most cases.
Salpingo-oophorectomy may be performed if the ovary is thought to be non-viable, if malignancy is suspected, or if the patient is post-menopausal. However, the frequency of malignant tumours is extremely low.[31]Rousseau V, Massicot R, Darwish AA, et al. Emergency management and conservative surgery of ovarian torsion in children: a report of 40 cases. J Pediatr Adolesc Gynecol. 2008 Aug;21(4):201-6. http://www.ncbi.nlm.nih.gov/pubmed/18656074?tool=bestpractice.com
Involvement of the fallopian tube in the torsion of the adnexa may significantly damage the tube, which may occasionally need to be surgically removed (salpingectomy).
Guidelines on adnexal torsion in adolescents recommend that surgeons should not remove a torsed ovary unless oophorectomy is unavoidable (e.g., when a severely necrotic ovary falls apart).[1]American College of Obstetricians and Gynecologists. Adnexal torsion in adolescents: ACOG committee opinion no, 783. Obstet Gynecol. 2019 Aug;134(2):e56-63. https://www.doi.org/10.1097/AOG.0000000000003373 http://www.ncbi.nlm.nih.gov/pubmed/31348225?tool=bestpractice.com
ovarian cystectomy
Additional treatment recommended for SOME patients in selected patient group
Cystectomy may be performed, either during the initial detorsion surgery or at a later date, in patients where ovarian torsion involves persistent ovarian cysts, depending on the type of cyst, patient characteristics, and the potential risk to the ovary of removing the cyst.
oophoropexy
Additional treatment recommended for SOME patients in selected patient group
As torsion of normal ovaries is more common in children, oophoropexy (a procedure to fix the ovary in position to limit its range of movement), either unilateral or bilateral, may be helpful at the time of surgery to prevent recurrence.[63]Germain M, Rarick T, Robins E. Management of intermittent ovarian torsion by laparoscopic oophoropexy. Obset Gynecol. 1996 Oct;88(4 Pt 2):715-7. http://www.ncbi.nlm.nih.gov/pubmed/8841265?tool=bestpractice.com [65]Crouch NS, Gyampoh B, Cutner AS, et al. Ovarian torsion: to pex or not to pex? Case report and review of the literature. J Pediatr Adolesc Gynecol. 2003 Dec;16(6):381-4. http://www.ncbi.nlm.nih.gov/pubmed/14642961?tool=bestpractice.com [66]Nagel TC, Sebastian J, Malo JW. Oophoropexy to prevent sequential or recurrent torsion. J Am Assoc Gynecol Laparosc. 1997 Aug;4(4):495-8. http://www.ncbi.nlm.nih.gov/pubmed/9224587?tool=bestpractice.com [67]Grunewald B, Keating J, Brown S. Asynchronous ovarian torsion - the case for prophylactic oophoropexy. Postgrad Med J. 1993 Apr;69(810):318-9. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2399654/pdf/postmedj00052-0067.pdf http://www.ncbi.nlm.nih.gov/pubmed/8321802?tool=bestpractice.com However, the benefit of oophoropexy remains uncertain.[25]Ritchie J, O’Mahony F, Garden A. Guideline for the management of ovarian cysts in children and adolescents. British Society for Paediatric & Adolescent Gynaecology. Dec 2018 [internet publication]. https://britspag.org/ovarian-cyst-guideline-in-pag/ [68]American College of Obstetricians and Gynecologists. Practice bulletin no. 174: evaluation and management of adnexal masses. Obstet Gynecol. 2016 Nov;128(5):e210-e226. http://www.ncbi.nlm.nih.gov/pubmed/27776072?tool=bestpractice.com [69]Nur Azurah AG, Zainol ZW, Zainuddin AA, et al. Update on the management of ovarian torsion in children and adolescents. World J Pediatr. 2015 Feb;11(1):35-40. http://www.ncbi.nlm.nih.gov/pubmed/25557598?tool=bestpractice.com One systematic review did not find clear evidence to support oophoropexy after a first episode of ovarian torsion.[52]Dasgupta R, Renaud E, Goldin AB, et al. Ovarian torsion in pediatric and adolescent patients: a systematic review. J Pediatr Surg. 2018 Jul;53(7):1387-91. http://www.ncbi.nlm.nih.gov/pubmed/29153467?tool=bestpractice.com Oophoropexy remains controversial; its use is not generally recommended as a means to decrease the risk of recurrent ovarian torsion.[1]American College of Obstetricians and Gynecologists. Adnexal torsion in adolescents: ACOG committee opinion no, 783. Obstet Gynecol. 2019 Aug;134(2):e56-63. https://www.doi.org/10.1097/AOG.0000000000003373 http://www.ncbi.nlm.nih.gov/pubmed/31348225?tool=bestpractice.com
Oophoropexy may be considered in specific settings; for example, absent contralateral ovary, elongated ovarian ligament, and torsion of normal adnexa.[62]Adeyemi-Fowode O, Lin EG, Syed F, et al. Adnexal torsion in children and adolescents: a retrospective review of 245 cases at a single institution. J Pediatr Adolesc Gynecol. 2019 Feb;32(1):64-9. https://www.doi.org/10.1016/j.jpag.2018.07.003 http://www.ncbi.nlm.nih.gov/pubmed/30012428?tool=bestpractice.com
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Please note that formulations/routes and doses may differ between drug names and brands, drug formularies, or locations. Treatment recommendations are specific to patient groups. See disclaimer
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