Large bowel obstruction
- Overview
- Theory
- Diagnosis
- Management
- Follow up
- Resources
Treatment algorithm
Please note that formulations/routes and doses may differ between drug names and brands, drug formularies, or locations. Treatment recommendations are specific to patient groups: see disclaimer
Look out for this icon: for treatment options that are affected, or added, as a result of your patient's comorbidities.
suspected or impending perforation
initial supportive care
Is the patient stable? Use an Airway, Breathing, Circulation, Disability, Exposure (ABCDE) approach to manage shock empirically.[42]Resuscitation Council (UK). The ABCDE approach. May 2021 [internet publication]. https://www.resus.org.uk/library/abcde-approach Ensure a patent airway and give oxygen if needed.
Treat the underlying cause as early as possible.
Escalate all patients with shock to a senior clinician.
See our topic Shock.
Manage peritonitis with urgent resuscitation and surgery within 6 hours.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide
When peritonitis is related to perforation proximal to a tumour site, patients are at higher risk of developing sepsis compared with patients where the perforation is at the tumour site.[5]Pisano M, Zorcolo L, Merli C, et al. 2017 WSES guidelines on colon and rectal cancer emergencies: obstruction and perforation. World J Emerg Surg. 2018 Aug 13;13:36. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090779 http://www.ncbi.nlm.nih.gov/pubmed/30123315?tool=bestpractice.com
Identify and manage any other complications from bowel obstruction, such as sepsis, urgently.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide See Sepsis in adults.
Practical tip
Sepsis
Think ' Could this be sepsis?' based on acute deterioration in an adult patient in whom there is clinical evidence or strong suspicion of infection.[25]NHS England. Sepsis guidance implementation advice for adults. Sep 2017 [internet publication]. https://www.england.nhs.uk/wp-content/uploads/2017/09/sepsis-guidance-implementation-advice-for-adults.pdf [26]National Institute for Health and Care Excellence. Suspected sepsis: recognition, diagnosis and early management. Mar 2024 [internet publication]. https://www.nice.org.uk/guidance/ng51 [27]Royal College of Physicians. National early warning score (NEWS) 2: standardising the assessment of acute-illness severity in the NHS. Dec 2017 [internet publication]. https://www.rcplondon.ac.uk/projects/outputs/national-early-warning-score-news-2
The patient may present with non-specific or non-localised symptoms (e.g., acutely unwell with a normal temperature) or there may be severe signs with evidence of multi-organ dysfunction and shock.[25]NHS England. Sepsis guidance implementation advice for adults. Sep 2017 [internet publication]. https://www.england.nhs.uk/wp-content/uploads/2017/09/sepsis-guidance-implementation-advice-for-adults.pdf [26]National Institute for Health and Care Excellence. Suspected sepsis: recognition, diagnosis and early management. Mar 2024 [internet publication]. https://www.nice.org.uk/guidance/ng51 [27]Royal College of Physicians. National early warning score (NEWS) 2: standardising the assessment of acute-illness severity in the NHS. Dec 2017 [internet publication]. https://www.rcplondon.ac.uk/projects/outputs/national-early-warning-score-news-2
Remember that sepsis represents the severe, life-threatening end of infection.[30]Inada-Kim M. Introducing the suspicion of sepsis insights dashboard. Royal College of Pathologists Bulletin. 2019 Apr;186;109.
Use a systematic approach (e.g., National Early Warning Score 2 [NEWS2]), alongside your clinical judgement, to assess the risk of deterioration due to sepsis.[25]NHS England. Sepsis guidance implementation advice for adults. Sep 2017 [internet publication]. https://www.england.nhs.uk/wp-content/uploads/2017/09/sepsis-guidance-implementation-advice-for-adults.pdf [27]Royal College of Physicians. National early warning score (NEWS) 2: standardising the assessment of acute-illness severity in the NHS. Dec 2017 [internet publication]. https://www.rcplondon.ac.uk/projects/outputs/national-early-warning-score-news-2 [28]Nutbeam T, Daniels R; The UK Sepsis Trust. Professional resources: clinical [internet publication]. https://sepsistrust.org/professional-resources/clinical [31]Evans L, Rhodes A, Alhazzani W, et al. Surviving Sepsis Campaign: international guidelines for management of sepsis and septic shock 2021. Crit Care Med. 2021 Nov 1;49(11):e1063-e143. https://www.doi.org/10.1097/CCM.0000000000005337 http://www.ncbi.nlm.nih.gov/pubmed/34605781?tool=bestpractice.com Consult local guidelines for the recommended approach at your institution.
Arrange urgent review by a senior clinical decision-maker (e.g., ST3 level doctor in the UK) if you suspect sepsis:[29]Academy of Medical Royal Colleges. Statement on the initial antimicrobial treatment of sepsis v2.0. October 2022 [internet publication]. https://www.aomrc.org.uk/reports-guidance/statement-on-the-initial-antimicrobial-treatment-of-sepsis-v2-0
Within 30 minutes for a patient who is critically ill (e.g., NEWS2 score of 7 or more, evidence of septic shock, or other significant clinical concerns)
A patient is also at high risk of severe illness or death from sepsis if they have a NEWS2 score below 7 and a single parameter contributes 3 points to their NEWS2 score and a medical review has confirmed that they are at high risk.
Within 1 hour for a patient who is severely ill (e.g., NEWS2 score of 5 or 6) or within 1 hour of any intervention for suspected sepsis (antibiotics/fluid resuscitation/oxygen) if there is no improvement in the patient’s condition.
Follow your local protocol for investigation and treatment of all patients with suspected sepsis, or those at risk. Start treatment promptly. Determine urgency of treatment according to likelihood of infection and severity of illness, or according to your local protocol.[29]Academy of Medical Royal Colleges. Statement on the initial antimicrobial treatment of sepsis v2.0. October 2022 [internet publication]. https://www.aomrc.org.uk/reports-guidance/statement-on-the-initial-antimicrobial-treatment-of-sepsis-v2-0 [31]Evans L, Rhodes A, Alhazzani W, et al. Surviving Sepsis Campaign: international guidelines for management of sepsis and septic shock 2021. Crit Care Med. 2021 Nov 1;49(11):e1063-e143. https://www.doi.org/10.1097/CCM.0000000000005337 http://www.ncbi.nlm.nih.gov/pubmed/34605781?tool=bestpractice.com
In the community and in custodial settings: refer for emergency medical care in hospital (usually by blue-light ambulance in the UK) any patient who is acutely ill with a suspected infection and is:[26]National Institute for Health and Care Excellence. Suspected sepsis: recognition, diagnosis and early management. Mar 2024 [internet publication]. https://www.nice.org.uk/guidance/ng51
Deemed to be at high risk of deterioration due to organ dysfunction (as measured by risk stratification)
At risk of neutropenic sepsis.
See Sepsis in adults.
Admit to hospital all patients with intestinal obstruction.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html
Treat initially in the accident and emergency department with intravenous fluid resuscitation, nasogastric intubation, and urethral catheterisation.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide Further management depends on the underlying cause of the obstruction. Maintain the patient as nil by mouth.
Fluid management
Measure and document the patient’s hydration status at presentation and throughout the admission.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html Aim to minimise the risk of acute kidney injury.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf See our topic Acute kidney injury.
Use intravenous fluids to treat patients with signs of shock or severe dehydration, or for maintenance in patients unable to tolerate oral fluids.
Indicators that the patient may need urgent fluid resuscitation include:[44]National Institute for Health and Care Excellence. Intravenous fluid therapy in adults in hospital. May 2017 [internet publication]. https://www.nice.org.uk/guidance/cg174
Systolic blood pressure less than 100 mmHg
Heart rate more than 90 beats per minute
Cold peripheries
Capillary refill time more than 2 seconds
Respiratory rate more than 20 breaths per minute
National Early Warning Score (NEWS2) of 5 or more
Passive leg-raising suggests fluid responsiveness.
Check local protocols for specific recommendations on fluid choice.
In patients receiving fluid resuscitation, place a catheter to monitor urine output.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide
Analgesia
Assess pain at presentation and throughout the admission.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html Provide analgesia in line with your local protocol.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html Use opiate analgesia, such as morphine sulphate, for acute abdominal pain.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [45]Manterola C, Vial M, Moraga J, et al. Analgesia in patients with acute abdominal pain. Cochrane Database Syst Rev. 2011 Jan 19;(1):CD005660. https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD005660.pub3/full http://www.ncbi.nlm.nih.gov/pubmed/21249672?tool=bestpractice.com Check your local protocols for specific advice on choice of drugs and doses. Refer to the acute pain team if the patient’s pain is difficult to manage, but ensure that this does not delay definitive treatment.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html
Primary options
morphine sulfate: 5-10 mg subcutaneously/intravenously/intramuscularly every 4 hours initially, adjust dose according to response
These drug options and doses relate to a patient with no comorbidities.
Primary options
morphine sulfate: 5-10 mg subcutaneously/intravenously/intramuscularly every 4 hours initially, adjust dose according to response
Drug choice, dose and interactions may be affected by the patient's comorbidities. Check your local drug formulary.
Show drug information for a patient with no comorbidities
Primary options
morphine sulfate
emergency surgery
Treatment recommended for ALL patients in selected patient group
Treat a suspected or imminent perforated bowel with emergency surgery without delay. Emergency surgery for large bowel obstruction is associated with a high morbidity and mortality.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide
The patient should be under the care of a colorectal surgeon within 24 hours of admission.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html
A consultant review should take place in all patients diagnosed with acute bowel obstruction as soon as clinically indicated and at the latest within 14 hours of admission to hospital.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html
The patient should have their risk of morbidity and mortality assessed and recorded in their medical records by a senior surgeon within 4 hours of admission or transfer.[43]Royal College of Surgeons of England. The high-risk general surgical patient: raising the standard. 2018 [internet publication]. https://www.rcseng.ac.uk/-/media/files/rcs/news-and-events/media-centre/2018-press-releases-documents/rcs-report-the-highrisk-general-surgical-patient--raising-the-standard--december-2018.pdf
Discuss ‘high-risk’ patients with a consultant within 1 hour.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf ‘High risk’ is defined as where the risk of mortality is greater than 10%, or where a patient is unstable and not responding to treatment.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide
Consult anaesthetic, critical care, and palliative care teams as well as surgery if needed.[33]NHS Scotland; Health Improvement Scotland. Scottish palliative care guidelines. December 2020 [internet publication]. https://www.palliativecareguidelines.scot.nhs.uk/guidelines/symptom-control/bowel-obstruction.aspx Bowel obstruction can be complex to manage. Multidisciplinary input is needed.[33]NHS Scotland; Health Improvement Scotland. Scottish palliative care guidelines. December 2020 [internet publication]. https://www.palliativecareguidelines.scot.nhs.uk/guidelines/symptom-control/bowel-obstruction.aspx Some hospital trusts offer a service for surgeons to liaise with geriatricians in order to optimise an older patient for surgery and reduce postoperative complications.
Prior to surgery, identify and treat any correctable comorbidities so that surgery is not delayed.
Assess the patient’s bleeding and venous thromboembolism (VTE) risk prior to surgery.[50]National Institute for Health and Care Excellence. Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism. August 2019 [internet publication]. https://www.nice.org.uk/guidance/ng89
Use a validated VTE prophylaxis tool. The National Institute for Health and Care Excellence in the UK states that a commonly used risk assessment tool for surgical patients is the UK Department of Health VTE risk assessment tool.[50]National Institute for Health and Care Excellence. Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism. August 2019 [internet publication]. https://www.nice.org.uk/guidance/ng89 Department of Health VTE risk assessment tool Opens in new window
Follow your local trust protocol for thromboprophylaxis.
Arrange a group and save.
Reassess the risk of bleeding and venous thromboembolism at the point of consultant review or if the patient’s clinical condition changes.
Assess the patient’s risk using appropriate risk prediction tools and your clinical judgement.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [43]Royal College of Surgeons of England. The high-risk general surgical patient: raising the standard. 2018 [internet publication]. https://www.rcseng.ac.uk/-/media/files/rcs/news-and-events/media-centre/2018-press-releases-documents/rcs-report-the-highrisk-general-surgical-patient--raising-the-standard--december-2018.pdf
The patient should have their risk of morbidity and mortality assessed and recorded in their medical records by a senior surgeon within 4 hours of admission or transfer.[43]Royal College of Surgeons of England. The high-risk general surgical patient: raising the standard. 2018 [internet publication]. https://www.rcseng.ac.uk/-/media/files/rcs/news-and-events/media-centre/2018-press-releases-documents/rcs-report-the-highrisk-general-surgical-patient--raising-the-standard--december-2018.pdf
Use a risk score recommended by your local protocol, such as the National Emergency Laparotomy Audit (NELA) risk model in the UK, to calculate a patient’s morbidity and mortality risk before surgery.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [51]Eugene N, Oliver CM, Bassett MG, et al. Development and internal validation of a novel risk adjustment model for adult patients undergoing emergency laparotomy surgery: the National Emergency Laparotomy Audit risk model. Br J Anaesth. 2018 Oct;121(4):739-48. https://bjanaesthesia.org/article/S0007-0912(18)30578-6/fulltext http://www.ncbi.nlm.nih.gov/pubmed/30236236?tool=bestpractice.com
The risk score can be used as a way to explain the risks of surgery to patients and their relatives, which enables shared decision-making and informed consent.
Give antibiotic prophylaxis in line with your local hospital protocol if surgery is needed.[52]National Institute for Health and Care Excellence. Surgical site infections: prevention and treatment. August 2020 [internet publication]. https://www.nice.org.uk/guidance/ng125 This is to reduce the risk of postoperative complications.
Practical tip
Bear in mind that closed loop obstruction can result in perforation and so should be treated as a surgical emergency.
Closed loop obstruction is when a single segment of bowel is obstructed at two sites. With gas trapped inside the bowel and continuing to enter the colon, pressure within the large bowel will continue to increase and cannot flow back into the small bowel. It leads to a rapid increase in distension and intraluminal pressure, with early vascular occlusion.[1]Griffiths S, Glancy DG. Intestinal obstruction. Intestinal Surg. 2020 Jan 1;38(1):43-50. https://www.surgeryjournal.co.uk/article/S0263-9319(19)30220-0/fulltext#secsectitle0010
The caecum is usually the site of perforation as it has the thinnest bowel wall.[1]Griffiths S, Glancy DG. Intestinal obstruction. Intestinal Surg. 2020 Jan 1;38(1):43-50. https://www.surgeryjournal.co.uk/article/S0263-9319(19)30220-0/fulltext#secsectitle0010
The aim of all operations for large bowel obstruction is to restore the flow of the faecal stream and to remove the obstructing lesion, if possible. This is often achieved through the formation of a stoma, either to defunction a downstream obstructing lesion or to avoid the risks inherent to anastomosis.
When deciding whether to make a stoma or form an anastomosis, the surgical team must take into account the severity of the illness and the patient’s condition under anaesthesia.
Bear in mind the morbidity and mortality risks of emergency colonic surgery.
Wherever possible, respect the patient’s wishes with regard to the formation of a stoma.
To treat an obstruction, the three main types of procedure are:
Right hemicolectomy: any operation that removes the ileocaecal valve and the caecum. The colonic resection can be limited to the caecum or extended to the descending colon
Hartmann’s procedure: involves the removal of the sigmoid colon with formation of a left iliac fossa colostomy. The rectal stump is closed. Theoretically reversible, but many patients opt not to undergo another major abdominal operation and, instead, keep their colostomy
Subtotal/total colectomy: carried out for obstructing lesions in the descending or sigmoid colon when the caecum has torn. For these lesions, it is not safe to just remove the obstruction, so subtotal colectomy is undertaken. An ileosigmoid or ileorectal anastomosis can be fashioned if the patient is well enough. Alternatively, an end ileostomy can be formed and the rectal stump oversewn.
malignancy
initial supportive care
Is the patient stable? Use an Airway, Breathing, Circulation, Disability, Exposure (ABCDE) approach to manage shock empirically.[42]Resuscitation Council (UK). The ABCDE approach. May 2021 [internet publication]. https://www.resus.org.uk/library/abcde-approach Ensure a patent airway and give oxygen if needed.
Treat the underlying cause as early as possible.
Escalate all patients with shock to a senior clinician.
See our topic Shock.
Manage peritonitis with urgent resuscitation and surgery within 6 hours.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide
Identify and manage any other complications from bowel obstruction, such as sepsis, urgently.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide See Sepsis in adults.
Practical tip
Sepsis
Think ' Could this be sepsis?' based on acute deterioration in an adult patient in whom there is clinical evidence or strong suspicion of infection.[25]NHS England. Sepsis guidance implementation advice for adults. Sep 2017 [internet publication]. https://www.england.nhs.uk/wp-content/uploads/2017/09/sepsis-guidance-implementation-advice-for-adults.pdf [26]National Institute for Health and Care Excellence. Suspected sepsis: recognition, diagnosis and early management. Mar 2024 [internet publication]. https://www.nice.org.uk/guidance/ng51 [27]Royal College of Physicians. National early warning score (NEWS) 2: standardising the assessment of acute-illness severity in the NHS. Dec 2017 [internet publication]. https://www.rcplondon.ac.uk/projects/outputs/national-early-warning-score-news-2
The patient may present with non-specific or non-localised symptoms (e.g., acutely unwell with a normal temperature) or there may be severe signs with evidence of multi-organ dysfunction and shock.[25]NHS England. Sepsis guidance implementation advice for adults. Sep 2017 [internet publication]. https://www.england.nhs.uk/wp-content/uploads/2017/09/sepsis-guidance-implementation-advice-for-adults.pdf [26]National Institute for Health and Care Excellence. Suspected sepsis: recognition, diagnosis and early management. Mar 2024 [internet publication]. https://www.nice.org.uk/guidance/ng51 [27]Royal College of Physicians. National early warning score (NEWS) 2: standardising the assessment of acute-illness severity in the NHS. Dec 2017 [internet publication]. https://www.rcplondon.ac.uk/projects/outputs/national-early-warning-score-news-2
Remember that sepsis represents the severe, life-threatening end of infection.[30]Inada-Kim M. Introducing the suspicion of sepsis insights dashboard. Royal College of Pathologists Bulletin. 2019 Apr;186;109.
Use a systematic approach (e.g., National Early Warning Score 2 [NEWS2]), alongside your clinical judgement, to assess the risk of deterioration due to sepsis.[25]NHS England. Sepsis guidance implementation advice for adults. Sep 2017 [internet publication]. https://www.england.nhs.uk/wp-content/uploads/2017/09/sepsis-guidance-implementation-advice-for-adults.pdf [26]National Institute for Health and Care Excellence. Suspected sepsis: recognition, diagnosis and early management. Mar 2024 [internet publication]. https://www.nice.org.uk/guidance/ng51 [27]Royal College of Physicians. National early warning score (NEWS) 2: standardising the assessment of acute-illness severity in the NHS. Dec 2017 [internet publication]. https://www.rcplondon.ac.uk/projects/outputs/national-early-warning-score-news-2 [28]Nutbeam T, Daniels R; The UK Sepsis Trust. Professional resources: clinical [internet publication]. https://sepsistrust.org/professional-resources/clinical [31]Evans L, Rhodes A, Alhazzani W, et al. Surviving Sepsis Campaign: international guidelines for management of sepsis and septic shock 2021. Crit Care Med. 2021 Nov 1;49(11):e1063-e143. https://www.doi.org/10.1097/CCM.0000000000005337 http://www.ncbi.nlm.nih.gov/pubmed/34605781?tool=bestpractice.com Consult local guidelines for the recommended approach at your institution.
Arrange urgent review by a senior clinical decision-maker (e.g., ST3 level doctor in the UK) if you suspect sepsis:[29]Academy of Medical Royal Colleges. Statement on the initial antimicrobial treatment of sepsis v2.0. October 2022 [internet publication]. https://www.aomrc.org.uk/reports-guidance/statement-on-the-initial-antimicrobial-treatment-of-sepsis-v2-0
Within 30 minutes for a patient who is critically ill (e.g., NEWS2 score of 7 or more, evidence of septic shock, or other significant clinical concerns)
A patient is also at high risk of severe illness or death from sepsis if they have a NEWS2 score below 7 and a single parameter contributes 3 points to their NEWS2 score and a medical review has confirmed that they are at high risk.
Within 1 hour for a patient who is severely ill (e.g., NEWS2 score of 5 or 6) or within 1 hour of any intervention for suspected sepsis (antibiotics/fluid resuscitation/oxygen) if there is no improvement in the patient’s condition.
Follow your local protocol for investigation and treatment of all patients with suspected sepsis, or those at risk. Start treatment promptly. Determine urgency of treatment according to likelihood of infection and severity of illness, or according to your local protocol.[29]Academy of Medical Royal Colleges. Statement on the initial antimicrobial treatment of sepsis v2.0. October 2022 [internet publication]. https://www.aomrc.org.uk/reports-guidance/statement-on-the-initial-antimicrobial-treatment-of-sepsis-v2-0 [31]Evans L, Rhodes A, Alhazzani W, et al. Surviving Sepsis Campaign: international guidelines for management of sepsis and septic shock 2021. Crit Care Med. 2021 Nov 1;49(11):e1063-e143. https://www.doi.org/10.1097/CCM.0000000000005337 http://www.ncbi.nlm.nih.gov/pubmed/34605781?tool=bestpractice.com
In the community and in custodial settings: refer for emergency medical care in hospital (usually by blue-light ambulance in the UK) any patient who is acutely ill with a suspected infection and is:[26]National Institute for Health and Care Excellence. Suspected sepsis: recognition, diagnosis and early management. Mar 2024 [internet publication]. https://www.nice.org.uk/guidance/ng51
Deemed to be at high risk of deterioration due to organ dysfunction (as measured by risk stratification)
At risk of neutropenic sepsis.
See Sepsis in adults.
Admit to hospital all patients with intestinal obstruction.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html
Treat initially in the accident and emergency department with intravenous fluid resuscitation, nasogastric intubation, and urethral catheterisation.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide Further management depends on the underlying cause of the obstruction. Maintain the patient as nil by mouth.
Fluid management
Measure and document the patient’s hydration status at presentation and throughout the admission.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html Aim to minimise the risk of acute kidney injury.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf See our topic Acute kidney injury.
Use intravenous fluids to treat patients with signs of shock or severe dehydration, or for maintenance in patients unable to tolerate oral fluids.
Indicators that the patient may need urgent fluid resuscitation include:[44]National Institute for Health and Care Excellence. Intravenous fluid therapy in adults in hospital. May 2017 [internet publication]. https://www.nice.org.uk/guidance/cg174
Systolic blood pressure less than 100 mmHg
Heart rate more than 90 beats per minute
Cold peripheries
Capillary refill time more than 2 seconds
Respiratory rate more than 20 breaths per minute
National Early Warning Score (NEWS2) of 5 or more
Passive leg-raising suggests fluid responsiveness.
Check local protocols for specific recommendations on fluid choice.
In patients receiving fluid resuscitation, place a catheter to monitor urine output.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide
Analgesia
Assess pain at presentation and throughout the admission.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html Provide analgesia in line with your local protocol.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html Use opiate analgesia, such as morphine sulphate, for acute abdominal pain.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [45]Manterola C, Vial M, Moraga J, et al. Analgesia in patients with acute abdominal pain. Cochrane Database Syst Rev. 2011 Jan 19;(1):CD005660. https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD005660.pub3/full http://www.ncbi.nlm.nih.gov/pubmed/21249672?tool=bestpractice.com Check your local protocols for specific advice on choice of drugs and doses. Refer to the acute pain team if the patient’s pain is difficult to manage, but ensure that this does not delay definitive treatment.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html
Primary options
morphine sulfate: 5-10 mg subcutaneously/intravenously/intramuscularly every 4 hours initially, adjust dose according to response
These drug options and doses relate to a patient with no comorbidities.
Primary options
morphine sulfate: 5-10 mg subcutaneously/intravenously/intramuscularly every 4 hours initially, adjust dose according to response
Drug choice, dose and interactions may be affected by the patient's comorbidities. Check your local drug formulary.
Show drug information for a patient with no comorbidities
Primary options
morphine sulfate
bowel decompression via nasogastric tube
Additional treatment recommended for SOME patients in selected patient group
Consider decompressing the bowel upstream of the obstruction via a nasogastric tube. This is generally required for patients with a distended small bowel or who are vomiting.
Place a nasogastric tube to decompress air/fluid in the upper gastrointestinal tract.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide This may prevent aerophagia and relieve nausea and vomiting.
Follow your local protocol for this procedure.
Aspirate the tube regularly to reduce the risk of aspiration.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide
Once the obstruction has been resolved, remove the tube as the patient’s clinical condition improves and as nasogastric aspirates decrease.
emergency stenting
Additional treatment recommended for SOME patients in selected patient group
Colonic stenting is an option for management of malignant obstruction.[2]Miller AS, Boyce K, Box B, et al. The Association of Coloproctology of Great Britain and Ireland consensus guidelines in emergency colorectal surgery. Colorectal Dis. 2021 Feb;23(2):476-547. https://pmc.ncbi.nlm.nih.gov/articles/PMC9291558 http://www.ncbi.nlm.nih.gov/pubmed/33470518?tool=bestpractice.com [3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [56]Ribeiro IB, de Moura DTH, Thompson CC, et al. Acute abdominal obstruction: colon stent or emergency surgery? An evidence-based review. World J Gastrointest Endosc. 2019 Mar 16;11(3):193-208. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425283 http://www.ncbi.nlm.nih.gov/pubmed/30918585?tool=bestpractice.com The other main option is surgery - see below.
Use in the absence of:[37]Association of Coloproctology of Great Britain and Ireland. Colorectal disease: position statements on malignant large bowel obstruction and anal fistula. July 2006 [internet publication]. https://www.acpgbi.org.uk//content/uploads/2017/08/Position-Statements-on-Malignant-Large-Bowel-Obstruction-Anal-Fistula.pdf [56]Ribeiro IB, de Moura DTH, Thompson CC, et al. Acute abdominal obstruction: colon stent or emergency surgery? An evidence-based review. World J Gastrointest Endosc. 2019 Mar 16;11(3):193-208. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425283 http://www.ncbi.nlm.nih.gov/pubmed/30918585?tool=bestpractice.com
Signs of sepsis or ischaemia
Perforation
Peritonitis
Closed loop obstruction
Intra-abdominal abscess
Caecum dilated more than 9 cm
Distal rectal lesions
Persistent coagulopathy.
Practical tip
Closed loop obstruction
Bear in mind that closed loop obstruction can result in perforation and so should be treated as a surgical emergency.
Closed loop obstruction is when a single segment of bowel is obstructed at two sites. With gas trapped inside the bowel and continuing to enter the colon, pressure within the large bowel will continue to increase and cannot flow back into the small bowel. It leads to a rapid increase in distension and intraluminal pressure, with early vascular occlusion.[1]Griffiths S, Glancy DG. Intestinal obstruction. Intestinal Surg. 2020 Jan 1;38(1):43-50. https://www.surgeryjournal.co.uk/article/S0263-9319(19)30220-0/fulltext#secsectitle0010
The caecum is usually the site of perforation as it has the thinnest bowel wall.[1]Griffiths S, Glancy DG. Intestinal obstruction. Intestinal Surg. 2020 Jan 1;38(1):43-50. https://www.surgeryjournal.co.uk/article/S0263-9319(19)30220-0/fulltext#secsectitle0010
Consider stenting for patients with acute left-sided malignant large bowel obstruction who are to be given palliative care.[53]National Institute for Health and Care Excellence. Colorectal cancer. December 2021 [internet publication]. https://www.nice.org.uk/guidance/ng151
For patients in whom curative surgery is planned, stenting may allow time to fully assess the patient and stabilise any comorbidities before proceeding.[2]Miller AS, Boyce K, Box B, et al. The Association of Coloproctology of Great Britain and Ireland consensus guidelines in emergency colorectal surgery. Colorectal Dis. 2021 Feb;23(2):476-547. https://pmc.ncbi.nlm.nih.gov/articles/PMC9291558 http://www.ncbi.nlm.nih.gov/pubmed/33470518?tool=bestpractice.com [53]National Institute for Health and Care Excellence. Colorectal cancer. December 2021 [internet publication]. https://www.nice.org.uk/guidance/ng151 This is described as using a stent to provide a 'bridge' to an elective procedure with less risk than emergency surgery.[2]Miller AS, Boyce K, Box B, et al. The Association of Coloproctology of Great Britain and Ireland consensus guidelines in emergency colorectal surgery. Colorectal Dis. 2021 Feb;23(2):476-547. https://pmc.ncbi.nlm.nih.gov/articles/PMC9291558 http://www.ncbi.nlm.nih.gov/pubmed/33470518?tool=bestpractice.com
Evidence: Use of colonic stenting as a bridge to surgery
Colonic stenting as a bridge to definitive surgery is an alternative option to emergency surgery for the management of acute left-sided large bowel obstruction in adults with suspected colorectal cancer. Stenting allows for optimisation of the patient’s condition pre-surgery and reduces the need for stoma formation; however, it may not always be technically successful and there is a risk of perforation.
In January 2020 the UK National Institute for Health and Care Excellence (NICE) updated its guideline on colorectal cancer to include evidence on the effectiveness of stenting compared with emergency surgery for adults with suspected colorectal cancer causing acute large bowel obstruction where curative surgery is planned.[54]National Institute for Health and Care Excellence. Effectiveness of stenting for acute large bowel obstruction. NICE guideline NG151 evidence review. January 2020 [internet publication]. https://www.nice.org.uk/guidance/ng151/evidence/c9-effectiveness-of-stenting-for-acute-large-bowel-obstruction-pdf-253058083670
NICE found seven randomised controlled trials (RCTs, n=469), two with follow-up studies, comparing stenting as a bridge to surgery with emergency surgery.
NICE included studies that all had low numbers of participants; the largest was the Enteral Stents for Colonic Obstruction (ESCO) trial with 115 participants. Two RCTs were stopped early - one due to excess morbidity in the emergency surgery arm and the other due to bowel perforation in the stenting arm.
Clinically successful bowel decompression was achieved in 69% of patients with stenting as a bridge to surgery (five RCTs, n=177, very low-quality evidence as assessed by GRADE).
There was a clinically important decrease in stoma rate post-procedure and at last follow-up (GRADE moderate). However, there was no clinically important difference in 30-day mortality (five RCTs, n=340, GRADE very low), disease-free survival at 4 to 5 years follow-up (two RCTS, n=106, GRADE low) or 3-year progression-free survival (one RCT, n=115, GRADE moderate).
Bowel perforation occurred in 10% of patients undergoing stenting (three RCTs, n=133, GRADE moderate) and stent failure in 18% (two RCTs, n=76, GRADE low).
The pre-publication results from the phase 3 UK ColoRectal Endoscopic Stenting Trial (CReST) were shared in confidence with the NICE guideline committee.
The results were consistent with the published evidence.
The NICE guideline committee concluded that the balance of benefits and harms was less clear for people where there was curative (as opposed to palliative) intent. However, the guideline committee also noted that stenting allows time to fully assess the patient and stabilise any comorbidities, thus reducing operative morbidity. This resulted in a strong recommendation to offer the option of either stenting or emergency surgery for people with acute left-sided large bowel obstruction if curative treatment is a possibility.
Also consider stenting for patients where extra-colonic tumours are causing bowel obstruction, such as in advanced gastric or ovarian cancer.[56]Ribeiro IB, de Moura DTH, Thompson CC, et al. Acute abdominal obstruction: colon stent or emergency surgery? An evidence-based review. World J Gastrointest Endosc. 2019 Mar 16;11(3):193-208. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425283 http://www.ncbi.nlm.nih.gov/pubmed/30918585?tool=bestpractice.com
Stenting should be performed only by an experienced endoscopist.[57]van Hooft JE, Veld JV, Arnold D, et al. Self-expandable metal stents for obstructing colonic and extracolonic cancer: European Society of Gastrointestinal Endoscopy (ESGE) guideline - update 2020. Endoscopy. 2020 May;52(5):389-407. https://www.thieme-connect.de/products/ejournals/abstract/10.1055/a-1140-3017 http://www.ncbi.nlm.nih.gov/pubmed/32259849?tool=bestpractice.com
Additional examination and imaging may be required to aid correct stent placement.[56]Ribeiro IB, de Moura DTH, Thompson CC, et al. Acute abdominal obstruction: colon stent or emergency surgery? An evidence-based review. World J Gastrointest Endosc. 2019 Mar 16;11(3):193-208. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425283 http://www.ncbi.nlm.nih.gov/pubmed/30918585?tool=bestpractice.com
Bowel preparation and sedation will be required prior to the procedure.
General anaesthesia may be required for stent placement in an obstructive emergency.[56]Ribeiro IB, de Moura DTH, Thompson CC, et al. Acute abdominal obstruction: colon stent or emergency surgery? An evidence-based review. World J Gastrointest Endosc. 2019 Mar 16;11(3):193-208. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425283 http://www.ncbi.nlm.nih.gov/pubmed/30918585?tool=bestpractice.com
After stent placement, prescribe stool softeners to prevent faecal impaction within the stent.[56]Ribeiro IB, de Moura DTH, Thompson CC, et al. Acute abdominal obstruction: colon stent or emergency surgery? An evidence-based review. World J Gastrointest Endosc. 2019 Mar 16;11(3):193-208. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425283 http://www.ncbi.nlm.nih.gov/pubmed/30918585?tool=bestpractice.com
Risks associated with stenting include stent migration, stent obstruction, perforation, haemorrhage, and pain.[56]Ribeiro IB, de Moura DTH, Thompson CC, et al. Acute abdominal obstruction: colon stent or emergency surgery? An evidence-based review. World J Gastrointest Endosc. 2019 Mar 16;11(3):193-208. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425283 http://www.ncbi.nlm.nih.gov/pubmed/30918585?tool=bestpractice.com
emergency surgery
Additional treatment recommended for SOME patients in selected patient group
Surgery is one of the two main options for the management of malignant obstruction. The other is stenting - see above.
Urgent surgery may be required.
The patient should be under the care of a colorectal surgeon within 24 hours of admission.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html
A consultant review should take place in all patients diagnosed with acute bowel obstruction as soon as clinically indicated and at the latest within 14 hours of admission to hospital.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html
The patient should have their risk of morbidity and mortality assessed and recorded in their medical records by a senior surgeon within 4 hours of admission or transfer.[43]Royal College of Surgeons of England. The high-risk general surgical patient: raising the standard. 2018 [internet publication]. https://www.rcseng.ac.uk/-/media/files/rcs/news-and-events/media-centre/2018-press-releases-documents/rcs-report-the-highrisk-general-surgical-patient--raising-the-standard--december-2018.pdf
Discuss ‘high-risk’ patients with a consultant within 1 hour.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html ‘High risk’ is defined as where the risk of mortality is greater than 10%, or where a patient is unstable and not responding to treatment.[23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html
Consult anaesthetic, critical care, and palliative care teams as well as surgery if needed.[33]NHS Scotland; Health Improvement Scotland. Scottish palliative care guidelines. December 2020 [internet publication]. https://www.palliativecareguidelines.scot.nhs.uk/guidelines/symptom-control/bowel-obstruction.aspx Bowel obstruction can be complex to manage. Multidisciplinary input is needed.[33]NHS Scotland; Health Improvement Scotland. Scottish palliative care guidelines. December 2020 [internet publication]. https://www.palliativecareguidelines.scot.nhs.uk/guidelines/symptom-control/bowel-obstruction.aspx
The surgeon will provide information on all of the treatment options available, such as surgery and palliative care, including the benefits, risks, and side-effects.[53]National Institute for Health and Care Excellence. Colorectal cancer. December 2021 [internet publication]. https://www.nice.org.uk/guidance/ng151
The surgeon will explain that open or laparoscopic surgery and a stoma may be required.
Side effects after surgery for colorectal cancer include pain; nerve damage; altered bowel, urinary, or sexual function; and anal discharge or bleeding.[53]National Institute for Health and Care Excellence. Colorectal cancer. December 2021 [internet publication]. https://www.nice.org.uk/guidance/ng151
Arrange for a trained stoma professional to provide information to the patient on the care and management of stomas and to mark the prospective site, if a stoma is required.[53]National Institute for Health and Care Excellence. Colorectal cancer. December 2021 [internet publication]. https://www.nice.org.uk/guidance/ng151
The aim of all operations for large bowel obstruction is to restore the flow of the faecal stream and to remove the obstructing lesion, if possible. This is often achieved through the formation of a stoma, either to defunction a downstream obstructing lesion or to avoid the risks inherent to anastomosis.
When deciding whether to make a stoma or form an anastomosis, the surgical team must take into account the severity of the illness and the patient’s condition under anaesthesia.
Bear in mind the morbidity and mortality risks of emergency colonic surgery.
Wherever possible, respect the patient’s wishes with regard to the formation of a stoma.
To treat an obstruction, the three main types of procedure are:
Right hemicolectomy: any operation that removes the ileocaecal valve and the caecum. The colonic resection can be limited to the caecum or extended to the descending colon
Hartmann’s procedure: involves the removal of the sigmoid colon with formation of a left iliac fossa colostomy. The rectal stump is closed. Theoretically reversible, but many patients opt not to undergo another major abdominal operation and, instead, keep their colostomy
Subtotal/total colectomy: carried out for obstructing lesions in the descending or sigmoid colon when the caecum has torn. For these lesions, it is not safe to just remove the obstruction, so subtotal colectomy is undertaken. An ileosigmoid or ileorectal anastomosis can be fashioned if the patient is well enough. Alternatively, an end ileostomy can be formed and the rectal stump oversewn.
Pre-surgical care
Prior to surgery, identify and treat any correctable comorbidities so that surgery is not delayed.
Assess the patient’s bleeding and venous thromboembolism (VTE) risk prior to surgery.[50]National Institute for Health and Care Excellence. Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism. August 2019 [internet publication]. https://www.nice.org.uk/guidance/ng89
Use a validated VTE prophylaxis tool. The National Institute for Health and Care Excellence in the UK states that a commonly used risk assessment tool for surgical patients is the UK Department of Health VTE risk assessment tool.[50]National Institute for Health and Care Excellence. Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism. August 2019 [internet publication]. https://www.nice.org.uk/guidance/ng89 Department of Health VTE risk assessment tool Opens in new window
Follow your local trust protocol for thromboprophylaxis.
Arrange a group and save.
Reassess the risk of bleeding and venous thromboembolism at the point of consultant review or if the patient’s clinical condition changes.
Assess the patient’s risk using appropriate risk prediction tools and your clinical judgement.[23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html [43]Royal College of Surgeons of England. The high-risk general surgical patient: raising the standard. 2018 [internet publication]. https://www.rcseng.ac.uk/-/media/files/rcs/news-and-events/media-centre/2018-press-releases-documents/rcs-report-the-highrisk-general-surgical-patient--raising-the-standard--december-2018.pdf
The patient should have their risk of morbidity and mortality assessed and recorded in their medical records by a senior surgeon within 4 hours of admission or transfer.[43]Royal College of Surgeons of England. The high-risk general surgical patient: raising the standard. 2018 [internet publication]. https://www.rcseng.ac.uk/-/media/files/rcs/news-and-events/media-centre/2018-press-releases-documents/rcs-report-the-highrisk-general-surgical-patient--raising-the-standard--december-2018.pdf
Use a risk score recommended by your local protocol, such as the National Emergency Laparotomy Audit (NELA) risk model in the UK, to calculate a patient’s morbidity and mortality risk before surgery.[23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html [51]Eugene N, Oliver CM, Bassett MG, et al. Development and internal validation of a novel risk adjustment model for adult patients undergoing emergency laparotomy surgery: the National Emergency Laparotomy Audit risk model. Br J Anaesth. 2018 Oct;121(4):739-48. https://bjanaesthesia.org/article/S0007-0912(18)30578-6/fulltext http://www.ncbi.nlm.nih.gov/pubmed/30236236?tool=bestpractice.com
The risk score can be used as a way to explain the risks of surgery to patients and their relatives, which enables shared decision-making and informed consent.
Give antibiotic prophylaxis in line with your local hospital protocol if surgery is needed.[52]National Institute for Health and Care Excellence. Surgical site infections: prevention and treatment. August 2020 [internet publication]. https://www.nice.org.uk/guidance/ng125 This is to reduce the risk of postoperative complications.
Ongoing care
Explain to the patient that they may experience emotional changes, feel anxious or depressed, or experience changes to their self-perception after cancer treatment, and signpost where they can receive help.[53]National Institute for Health and Care Excellence. Colorectal cancer. December 2021 [internet publication]. https://www.nice.org.uk/guidance/ng151
Prior to discharge, advise on:[53]National Institute for Health and Care Excellence. Colorectal cancer. December 2021 [internet publication]. https://www.nice.org.uk/guidance/ng151
Adapting physical activity as needed
Diet - in particular, advice on foods that may cause diarrhoea, flatulence, incontinence, or difficulty emptying the bowels
Weight management
Smoking and alcohol use
Expectations for recovery
How to seek help for any side effects.
palliative care
Additional treatment recommended for SOME patients in selected patient group
Make management decisions with the appropriate multidisciplinary team and involve the patient and/or their carers where possible. Regarding any acute care, consider the patient’s resuscitation status and any agreed ceilings of care in place. If the patient is at the end of life, take treatment and monitoring decisions in accordance with an end-of-life care pathway.
Consider whether or not surgery is indicated for the individual patient receiving palliative care. Bear in mind the patient’s condition and their preferences, as well as the benefits and risks when considering surgery.[33]NHS Scotland; Health Improvement Scotland. Scottish palliative care guidelines. December 2020 [internet publication]. https://www.palliativecareguidelines.scot.nhs.uk/guidelines/symptom-control/bowel-obstruction.aspx
Factors that may suggest surgery is not indicated:[33]NHS Scotland; Health Improvement Scotland. Scottish palliative care guidelines. December 2020 [internet publication]. https://www.palliativecareguidelines.scot.nhs.uk/guidelines/symptom-control/bowel-obstruction.aspx [55]Binet Q, Duck L. Management of end-stage malignant bowel obstruction: an evidence-based review of clinical practice. Belg J Med Oncol. 2019;13(4):123-8. https://www.ariez.nl/wp-content/uploads/2019/06/BJMO4-2019_Art._Duck_Review-Oncology.pdf [58]Madariaga A, Lau J, Ghoshal A, et al. MASCC multidisciplinary evidence-based recommendations for the management of malignant bowel obstruction in advanced cancer. Support Care Cancer. 2022 Jun;30(6):4711-28. https://pmc.ncbi.nlm.nih.gov/articles/PMC9046338 http://www.ncbi.nlm.nih.gov/pubmed/35274188?tool=bestpractice.com
Known diffuse intra-abdominal cancer (seen during surgery or on imaging)
Diffuse, palpable intra-abdominal masses
Massive ascites that recurs rapidly after drainage
High obstruction involving the proximal stomach
Extensive metastatic disease outside the abdomen
Patient with poor performance or nutritional status
Previous radiotherapy to the abdomen or pelvis
Small bowel obstruction at multiple sites.
If an acute problem, consider conservative management and watchful waiting.[33]NHS Scotland; Health Improvement Scotland. Scottish palliative care guidelines. December 2020 [internet publication]. https://www.palliativecareguidelines.scot.nhs.uk/guidelines/symptom-control/bowel-obstruction.aspx Ensure the patient is nil by mouth in order to rest the bowel. Relieve symptoms with:[33]NHS Scotland; Health Improvement Scotland. Scottish palliative care guidelines. December 2020 [internet publication]. https://www.palliativecareguidelines.scot.nhs.uk/guidelines/symptom-control/bowel-obstruction.aspx [58]Madariaga A, Lau J, Ghoshal A, et al. MASCC multidisciplinary evidence-based recommendations for the management of malignant bowel obstruction in advanced cancer. Support Care Cancer. 2022 Jun;30(6):4711-28. https://pmc.ncbi.nlm.nih.gov/articles/PMC9046338 http://www.ncbi.nlm.nih.gov/pubmed/35274188?tool=bestpractice.com
Laxatives for constipation
A nasogastric tube as a short-term measure to control vomiting
Ice to suck to moisten the mouth and lips, and to manage a sense of thirst.
In a dehydrated patient, use intravenous rehydration initially and subcutaneous rehydration for longer-term management.[33]NHS Scotland; Health Improvement Scotland. Scottish palliative care guidelines. December 2020 [internet publication]. https://www.palliativecareguidelines.scot.nhs.uk/guidelines/symptom-control/bowel-obstruction.aspx
Consider stenting to treat a localised obstruction in the colon.[33]NHS Scotland; Health Improvement Scotland. Scottish palliative care guidelines. December 2020 [internet publication]. https://www.palliativecareguidelines.scot.nhs.uk/guidelines/symptom-control/bowel-obstruction.aspx [58]Madariaga A, Lau J, Ghoshal A, et al. MASCC multidisciplinary evidence-based recommendations for the management of malignant bowel obstruction in advanced cancer. Support Care Cancer. 2022 Jun;30(6):4711-28. https://pmc.ncbi.nlm.nih.gov/articles/PMC9046338 http://www.ncbi.nlm.nih.gov/pubmed/35274188?tool=bestpractice.com
Treat a mechanical obstruction or an obstruction due to peristaltic failure with medication.
For peristaltic failure:[33]NHS Scotland; Health Improvement Scotland. Scottish palliative care guidelines. December 2020 [internet publication]. https://www.palliativecareguidelines.scot.nhs.uk/guidelines/symptom-control/bowel-obstruction.aspx [58]Madariaga A, Lau J, Ghoshal A, et al. MASCC multidisciplinary evidence-based recommendations for the management of malignant bowel obstruction in advanced cancer. Support Care Cancer. 2022 Jun;30(6):4711-28. https://pmc.ncbi.nlm.nih.gov/articles/PMC9046338 http://www.ncbi.nlm.nih.gov/pubmed/35274188?tool=bestpractice.com
Stop any medications that the patient is taking that reduce peristalsis, such as cyclizine, hyoscine, 5HT3 antagonists, or amitriptyline.
Treat constipation with laxatives.
Use a prokinetic antiemetic, such as metoclopramide.
Stop the medication if colic develops.
Use prolonged higher doses with caution and monitor for extrapyramidal side effects.
Consider a fentanyl transdermal patch for pain control as it is less constipating than morphine or oxycodone.
For mechanical obstruction:[33]NHS Scotland; Health Improvement Scotland. Scottish palliative care guidelines. December 2020 [internet publication]. https://www.palliativecareguidelines.scot.nhs.uk/guidelines/symptom-control/bowel-obstruction.aspx [58]Madariaga A, Lau J, Ghoshal A, et al. MASCC multidisciplinary evidence-based recommendations for the management of malignant bowel obstruction in advanced cancer. Support Care Cancer. 2022 Jun;30(6):4711-28. https://pmc.ncbi.nlm.nih.gov/articles/PMC9046338 http://www.ncbi.nlm.nih.gov/pubmed/35274188?tool=bestpractice.com
Treat constipation with laxatives
Avoid stimulant laxatives if the patient has colic
Stop all laxatives in complete obstruction
Consider parenteral dexamethasone to reverse partial obstruction.
screening and monitoring
Treatment recommended for ALL patients in selected patient group
Monitor the patient using an early warning score, such as the National Early Warning Score 2 (NEWS2) score. NEWS2 measures:[27]Royal College of Physicians. National early warning score (NEWS) 2: standardising the assessment of acute-illness severity in the NHS. Dec 2017 [internet publication]. https://www.rcplondon.ac.uk/projects/outputs/national-early-warning-score-news-2 NEWS2 Opens in new window
Respiration rate
Oxygen saturation
Systolic blood pressure
Pulse rate
Level of consciousness or new-onset confusion
Temperature.
Undertake a nutritional screen, such as the Malnutrition Universal Screening Tool (MUST) score, and act on the results.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html [48]National Institute for Health and Care Excellence. Nutrition support for adults: oral nutrition support, enteral tube feeding and parenteral nutrition. August 2017 [internet publication]. https://www.nice.org.uk/guidance/cg32 MUST calculator Opens in new window Provide nutritional support, if indicated.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [48]National Institute for Health and Care Excellence. Nutrition support for adults: oral nutrition support, enteral tube feeding and parenteral nutrition. August 2017 [internet publication]. https://www.nice.org.uk/guidance/cg32 Arrange review by a dietitian or the nutrition team.[23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html Consider nutritional support if the patient has not eaten for 5 days and/or may not be able to resume their usual diet within the next 5 days, or if the patient has a poor absorptive capacity.[48]National Institute for Health and Care Excellence. Nutrition support for adults: oral nutrition support, enteral tube feeding and parenteral nutrition. August 2017 [internet publication]. https://www.nice.org.uk/guidance/cg32
Assess frailty using a score, such as the Rockwood frailty score.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html [49]Rockwood K, Song X, MacKnight C, et al. A global clinical measure of fitness and frailty in elderly people. CMAJ. 2005 Aug 30;173(5):489-95. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1188185 http://www.ncbi.nlm.nih.gov/pubmed/16129869?tool=bestpractice.com Clinical Frailty Scale Opens in new window
Discuss patients with a high frailty score with the multidisciplinary team.
Establish a treatment escalation plan and record resuscitation status.
Arrange a risk assessment, with input from critical care where necessary.[23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html
volvulus
initial supportive care
Is the patient stable? Use an Airway, Breathing, Circulation, Disability, Exposure (ABCDE) approach to manage shock empirically.[42]Resuscitation Council (UK). The ABCDE approach. May 2021 [internet publication]. https://www.resus.org.uk/library/abcde-approach Ensure a patent airway and give oxygen if needed.
Treat the underlying cause as early as possible.
Escalate all patients with shock to a senior clinician.
See our topic Shock.
Manage peritonitis with urgent resuscitation and surgery within 6 hours.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide
Identify and manage any other complications from bowel obstruction, such as sepsis, urgently.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide See Sepsis in adults.
Practical tip
Sepsis
Think ' Could this be sepsis?' based on acute deterioration in an adult patient in whom there is clinical evidence or strong suspicion of infection.[25]NHS England. Sepsis guidance implementation advice for adults. Sep 2017 [internet publication]. https://www.england.nhs.uk/wp-content/uploads/2017/09/sepsis-guidance-implementation-advice-for-adults.pdf [26]National Institute for Health and Care Excellence. Suspected sepsis: recognition, diagnosis and early management. Mar 2024 [internet publication]. https://www.nice.org.uk/guidance/ng51 [27]Royal College of Physicians. National early warning score (NEWS) 2: standardising the assessment of acute-illness severity in the NHS. Dec 2017 [internet publication]. https://www.rcplondon.ac.uk/projects/outputs/national-early-warning-score-news-2
The patient may present with non-specific or non-localised symptoms (e.g., acutely unwell with a normal temperature) or there may be severe signs with evidence of multi-organ dysfunction and shock.[25]NHS England. Sepsis guidance implementation advice for adults. Sep 2017 [internet publication]. https://www.england.nhs.uk/wp-content/uploads/2017/09/sepsis-guidance-implementation-advice-for-adults.pdf [26]National Institute for Health and Care Excellence. Suspected sepsis: recognition, diagnosis and early management. Mar 2024 [internet publication]. https://www.nice.org.uk/guidance/ng51 [27]Royal College of Physicians. National early warning score (NEWS) 2: standardising the assessment of acute-illness severity in the NHS. Dec 2017 [internet publication]. https://www.rcplondon.ac.uk/projects/outputs/national-early-warning-score-news-2
Remember that sepsis represents the severe, life-threatening end of infection.[30]Inada-Kim M. Introducing the suspicion of sepsis insights dashboard. Royal College of Pathologists Bulletin. 2019 Apr;186;109.
Use a systematic approach (e.g., National Early Warning Score 2 [NEWS2]), alongside your clinical judgement, to assess the risk of deterioration due to sepsis.[25]NHS England. Sepsis guidance implementation advice for adults. Sep 2017 [internet publication]. https://www.england.nhs.uk/wp-content/uploads/2017/09/sepsis-guidance-implementation-advice-for-adults.pdf [26]National Institute for Health and Care Excellence. Suspected sepsis: recognition, diagnosis and early management. Mar 2024 [internet publication]. https://www.nice.org.uk/guidance/ng51 [27]Royal College of Physicians. National early warning score (NEWS) 2: standardising the assessment of acute-illness severity in the NHS. Dec 2017 [internet publication]. https://www.rcplondon.ac.uk/projects/outputs/national-early-warning-score-news-2 [28]Nutbeam T, Daniels R; The UK Sepsis Trust. Professional resources: clinical [internet publication]. https://sepsistrust.org/professional-resources/clinical [31]Evans L, Rhodes A, Alhazzani W, et al. Surviving Sepsis Campaign: international guidelines for management of sepsis and septic shock 2021. Crit Care Med. 2021 Nov 1;49(11):e1063-e143. https://www.doi.org/10.1097/CCM.0000000000005337 http://www.ncbi.nlm.nih.gov/pubmed/34605781?tool=bestpractice.com Consult local guidelines for the recommended approach at your institution.
Arrange urgent review by a senior clinical decision-maker (e.g., ST3 level doctor in the UK) if you suspect sepsis:[29]Academy of Medical Royal Colleges. Statement on the initial antimicrobial treatment of sepsis v2.0. October 2022 [internet publication]. https://www.aomrc.org.uk/reports-guidance/statement-on-the-initial-antimicrobial-treatment-of-sepsis-v2-0
Within 30 minutes for a patient who is critically ill (e.g., NEWS2 score of 7 or more, evidence of septic shock, or other significant clinical concerns)
A patient is also at high risk of severe illness or death from sepsis if they have a NEWS2 score below 7 and a single parameter contributes 3 points to their NEWS2 score and a medical review has confirmed that they are at high risk.
Within 1 hour for a patient who is severely ill (e.g., NEWS2 score of 5 or 6) or within 1 hour of any intervention for suspected sepsis (antibiotics/fluid resuscitation/oxygen) if there is no improvement in the patient’s condition.
Follow your local protocol for investigation and treatment of all patients with suspected sepsis, or those at risk. Start treatment promptly. Determine urgency of treatment according to likelihood of infection and severity of illness, or according to your local protocol.[29]Academy of Medical Royal Colleges. Statement on the initial antimicrobial treatment of sepsis v2.0. October 2022 [internet publication]. https://www.aomrc.org.uk/reports-guidance/statement-on-the-initial-antimicrobial-treatment-of-sepsis-v2-0 [31]Evans L, Rhodes A, Alhazzani W, et al. Surviving Sepsis Campaign: international guidelines for management of sepsis and septic shock 2021. Crit Care Med. 2021 Nov 1;49(11):e1063-e143. https://www.doi.org/10.1097/CCM.0000000000005337 http://www.ncbi.nlm.nih.gov/pubmed/34605781?tool=bestpractice.com
In the community and in custodial settings: refer for emergency medical care in hospital (usually by blue-light ambulance in the UK) any patient who is acutely ill with a suspected infection and is:[26]National Institute for Health and Care Excellence. Suspected sepsis: recognition, diagnosis and early management. Mar 2024 [internet publication]. https://www.nice.org.uk/guidance/ng51
Deemed to be at high risk of deterioration due to organ dysfunction (as measured by risk stratification)
At risk of neutropenic sepsis.
See Sepsis in adults.
Admit to hospital all patients with intestinal obstruction.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html
Treat initially in the accident and emergency department with intravenous fluid resuscitation, nasogastric intubation, and urethral catheterisation.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide Further management depends on the underlying cause of the obstruction. Maintain the patient as nil by mouth.
Fluid management
Measure and document the patient’s hydration status at presentation and throughout the admission.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html Aim to minimise the risk of acute kidney injury.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf See our topic Acute kidney injury.
Use intravenous fluids to treat patients with signs of shock or severe dehydration, or for maintenance in patients unable to tolerate oral fluids.
Indicators that the patient may need urgent fluid resuscitation include:[44]National Institute for Health and Care Excellence. Intravenous fluid therapy in adults in hospital. May 2017 [internet publication]. https://www.nice.org.uk/guidance/cg174
Systolic blood pressure less than 100 mmHg
Heart rate more than 90 beats per minute
Cold peripheries
Capillary refill time more than 2 seconds
Respiratory rate more than 20 breaths per minute
National Early Warning Score (NEWS2) of 5 or more
Passive leg-raising suggests fluid responsiveness.
Check local protocols for specific recommendations on fluid choice.
In patients receiving fluid resuscitation, place a catheter to monitor urine output.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide
Analgesia
Assess pain at presentation and throughout the admission.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html Provide analgesia in line with your local protocol.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html Use opiate analgesia, such as morphine sulphate, for acute abdominal pain.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [45]Manterola C, Vial M, Moraga J, et al. Analgesia in patients with acute abdominal pain. Cochrane Database Syst Rev. 2011 Jan 19;(1):CD005660. https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD005660.pub3/full http://www.ncbi.nlm.nih.gov/pubmed/21249672?tool=bestpractice.com Check your local protocols for specific advice on choice of drugs and doses. Refer to the acute pain team if the patient’s pain is difficult to manage, but ensure that this does not delay definitive treatment.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html
Primary options
morphine sulfate: 5-10 mg subcutaneously/intravenously/intramuscularly every 4 hours initially, adjust dose according to response
These drug options and doses relate to a patient with no comorbidities.
Primary options
morphine sulfate: 5-10 mg subcutaneously/intravenously/intramuscularly every 4 hours initially, adjust dose according to response
Drug choice, dose and interactions may be affected by the patient's comorbidities. Check your local drug formulary.
Show drug information for a patient with no comorbidities
Primary options
morphine sulfate
bowel decompression via nasogastric tube
Additional treatment recommended for SOME patients in selected patient group
Consider decompressing the bowel upstream of the obstruction via a nasogastric tube. This is generally required for patients with a distended small bowel or who are vomiting.
Place a nasogastric tube to decompress air/fluid in the upper gastrointestinal tract.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide This may prevent aerophagia and relieve nausea and vomiting.
Follow your local protocol for this procedure.
Aspirate the tube regularly to reduce the risk of aspiration.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide
Once the obstruction has been resolved, remove the tube as the patient’s clinical condition improves and as nasogastric aspirates decrease.
urgent flexible sigmoidoscopy
Additional treatment recommended for SOME patients in selected patient group
Treat urgently, because of the risk of perforation due to ischaemia or due to the obstruction itself.
Treat with endoscopic decompression using a flexible sigmoidoscope and refer for surgery if decompression fails.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [9]Tian BWCA, Vigutto G, Tan E, et al. WSES consensus guidelines on sigmoid volvulus management. World J Emerg Surg. 2023 May 15;18(1):34. https://pmc.ncbi.nlm.nih.gov/articles/PMC10186802 http://www.ncbi.nlm.nih.gov/pubmed/37189134?tool=bestpractice.com [32]Lou Z, Yu ED, Zhang W, et al. Appropriate treatment of acute sigmoid volvulus in the emergency setting. World J Gastroenterol. 2013 Aug 14;19(30):4979-83. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740429 http://www.ncbi.nlm.nih.gov/pubmed/23946604?tool=bestpractice.com
Often endoscopic decompression using flexible sigmoidoscopy allows the twist in the bowel to be untwisted and the obstruction to be relieved.[9]Tian BWCA, Vigutto G, Tan E, et al. WSES consensus guidelines on sigmoid volvulus management. World J Emerg Surg. 2023 May 15;18(1):34. https://pmc.ncbi.nlm.nih.gov/articles/PMC10186802 http://www.ncbi.nlm.nih.gov/pubmed/37189134?tool=bestpractice.com
Be aware that this can introduce more gas into the large bowel and increase the distention in the case of a stricture.
Continue appropriate supportive care such as fluid resuscitation to prevent or treat any adverse consequences, such as high intestinal fluid accumulation, electrolyte disturbances, and hypoproteinaemia.[32]Lou Z, Yu ED, Zhang W, et al. Appropriate treatment of acute sigmoid volvulus in the emergency setting. World J Gastroenterol. 2013 Aug 14;19(30):4979-83. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740429 http://www.ncbi.nlm.nih.gov/pubmed/23946604?tool=bestpractice.com Recurrence can occur and, if so, the sigmoidoscopy can be repeated.[32]Lou Z, Yu ED, Zhang W, et al. Appropriate treatment of acute sigmoid volvulus in the emergency setting. World J Gastroenterol. 2013 Aug 14;19(30):4979-83. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740429 http://www.ncbi.nlm.nih.gov/pubmed/23946604?tool=bestpractice.com
Consider whether elective resection is indicated after endoscopic decompression.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [9]Tian BWCA, Vigutto G, Tan E, et al. WSES consensus guidelines on sigmoid volvulus management. World J Emerg Surg. 2023 May 15;18(1):34. https://pmc.ncbi.nlm.nih.gov/articles/PMC10186802 http://www.ncbi.nlm.nih.gov/pubmed/37189134?tool=bestpractice.com
emergency surgery
Additional treatment recommended for SOME patients in selected patient group
Emergency surgery is the primary treatment option where perforation or peritonitis is suspected in a patient with volvulus.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [32]Lou Z, Yu ED, Zhang W, et al. Appropriate treatment of acute sigmoid volvulus in the emergency setting. World J Gastroenterol. 2013 Aug 14;19(30):4979-83. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740429 http://www.ncbi.nlm.nih.gov/pubmed/23946604?tool=bestpractice.com
The patient should be under the care of a colorectal surgeon within 24 hours of admission.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html
A consultant review should take place in all patients diagnosed with acute bowel obstruction as soon as clinically indicated and at the latest within 14 hours of admission to hospital.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html
The patient should have their risk of morbidity and mortality assessed and recorded in their medical records by a senior surgeon within 4 hours of admission or transfer.[43]Royal College of Surgeons of England. The high-risk general surgical patient: raising the standard. 2018 [internet publication]. https://www.rcseng.ac.uk/-/media/files/rcs/news-and-events/media-centre/2018-press-releases-documents/rcs-report-the-highrisk-general-surgical-patient--raising-the-standard--december-2018.pdf
Discuss ‘high-risk’ patients with a consultant within 1 hour.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html ‘High risk’ is defined as where the risk of mortality is greater than 10%, or where a patient is unstable and not responding to treatment.[23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html
Consult anaesthetic, critical care, and palliative care teams as well as surgery if needed.[33]NHS Scotland; Health Improvement Scotland. Scottish palliative care guidelines. December 2020 [internet publication]. https://www.palliativecareguidelines.scot.nhs.uk/guidelines/symptom-control/bowel-obstruction.aspx Bowel obstruction can be complex to manage. Multidisciplinary input is needed.[33]NHS Scotland; Health Improvement Scotland. Scottish palliative care guidelines. December 2020 [internet publication]. https://www.palliativecareguidelines.scot.nhs.uk/guidelines/symptom-control/bowel-obstruction.aspx Some hospital trusts offer a service for surgeons to liaise with geriatricians in order to optimise an older patient for surgery and reduce postoperative complications.
The aim of all operations for large bowel obstruction is to restore the flow of the faecal stream and to remove the obstructing lesion, if possible. This is often achieved through the formation of a stoma, either to defunction a downstream obstructing lesion or to avoid the risks inherent to anastomosis.
When deciding whether to make a stoma or form an anastomosis, the surgical team must take into account the severity of the illness and the patient’s condition under anaesthesia.
Bear in mind the morbidity and mortality risks of emergency colonic surgery.
Wherever possible, respect the patient’s wishes with regard to the formation of a stoma.
To treat an obstruction, the three main types of procedure are:
Right hemicolectomy: any operation that removes the ileocaecal valve and the caecum. The colonic resection can be limited to the caecum or extended to the descending colon
Hartmann’s procedure: involves the removal of the sigmoid colon with formation of a left iliac fossa colostomy. The rectal stump is closed. Theoretically reversible, but many patients opt not to undergo another major abdominal operation and, instead, keep their colostomy
Subtotal/total colectomy: carried out for obstructing lesions in the descending or sigmoid colon when the caecum has torn. For these lesions, it is not safe to just remove the obstruction, so subtotal colectomy is undertaken. An ileosigmoid or ileorectal anastomosis can be fashioned if the patient is well enough. Alternatively, an end ileostomy can be formed and the rectal stump oversewn.
Pre-surgical care
Prior to surgery, identify and treat any correctable comorbidities so that surgery is not delayed.
Assess the patient’s bleeding and venous thromboembolism (VTE) risk prior to surgery.[50]National Institute for Health and Care Excellence. Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism. August 2019 [internet publication]. https://www.nice.org.uk/guidance/ng89
Use a validated VTE prophylaxis tool. The National Institute for Health and Care Excellence in the UK states that a commonly used risk assessment tool for surgical patients is the UK Department of Health VTE risk assessment tool.[50]National Institute for Health and Care Excellence. Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism. August 2019 [internet publication]. https://www.nice.org.uk/guidance/ng89 Department of Health VTE risk assessment tool Opens in new window
Follow your local trust protocol for thromboprophylaxis.
Arrange a group and save.
Reassess the risk of bleeding and venous thromboembolism at the point of consultant review or if the patient’s clinical condition changes.
Assess the patient’s risk using appropriate risk prediction tools and your clinical judgement.[23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html [43]Royal College of Surgeons of England. The high-risk general surgical patient: raising the standard. 2018 [internet publication]. https://www.rcseng.ac.uk/-/media/files/rcs/news-and-events/media-centre/2018-press-releases-documents/rcs-report-the-highrisk-general-surgical-patient--raising-the-standard--december-2018.pdf
The patient should have their risk of morbidity and mortality assessed and recorded in their medical records by a senior surgeon within 4 hours of admission or transfer.[43]Royal College of Surgeons of England. The high-risk general surgical patient: raising the standard. 2018 [internet publication]. https://www.rcseng.ac.uk/-/media/files/rcs/news-and-events/media-centre/2018-press-releases-documents/rcs-report-the-highrisk-general-surgical-patient--raising-the-standard--december-2018.pdf
Use a risk score recommended by your local protocol, such as the National Emergency Laparotomy Audit (NELA) risk model in the UK, to calculate a patient’s morbidity and mortality risk before surgery.[23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html [51]Eugene N, Oliver CM, Bassett MG, et al. Development and internal validation of a novel risk adjustment model for adult patients undergoing emergency laparotomy surgery: the National Emergency Laparotomy Audit risk model. Br J Anaesth. 2018 Oct;121(4):739-48. https://bjanaesthesia.org/article/S0007-0912(18)30578-6/fulltext http://www.ncbi.nlm.nih.gov/pubmed/30236236?tool=bestpractice.com
The risk score can be used as a way to explain the risks of surgery to patients and their relatives, which enables shared decision-making and informed consent.
Give antibiotic prophylaxis in line with your local hospital protocol if surgery is needed.[52]National Institute for Health and Care Excellence. Surgical site infections: prevention and treatment. August 2020 [internet publication]. https://www.nice.org.uk/guidance/ng125 This is to reduce the risk of postoperative complications.
screening and monitoring
Treatment recommended for ALL patients in selected patient group
Monitor the patient using an early warning score, such as the National Early Warning Score 2 (NEWS2) score. NEWS2 measures:[27]Royal College of Physicians. National early warning score (NEWS) 2: standardising the assessment of acute-illness severity in the NHS. Dec 2017 [internet publication]. https://www.rcplondon.ac.uk/projects/outputs/national-early-warning-score-news-2 NEWS2 Opens in new window
Respiration rate
Oxygen saturation
Systolic blood pressure
Pulse rate
Level of consciousness or new-onset confusion
Temperature.
Undertake a nutritional screen, such as the Malnutrition Universal Screening Tool (MUST) score, and act on the results.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html [48]National Institute for Health and Care Excellence. Nutrition support for adults: oral nutrition support, enteral tube feeding and parenteral nutrition. August 2017 [internet publication]. https://www.nice.org.uk/guidance/cg32 MUST calculator Opens in new window Provide nutritional support, if indicated.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [48]National Institute for Health and Care Excellence. Nutrition support for adults: oral nutrition support, enteral tube feeding and parenteral nutrition. August 2017 [internet publication]. https://www.nice.org.uk/guidance/cg32 Arrange review by a dietitian or the nutrition team.[23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html Consider nutritional support if the patient has not eaten for 5 days and/or may not be able to resume their usual diet within the next 5 days, or if the patient has a poor absorptive capacity.[48]National Institute for Health and Care Excellence. Nutrition support for adults: oral nutrition support, enteral tube feeding and parenteral nutrition. August 2017 [internet publication]. https://www.nice.org.uk/guidance/cg32
Assess frailty using a score, such as the Rockwood frailty score.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html [49]Rockwood K, Song X, MacKnight C, et al. A global clinical measure of fitness and frailty in elderly people. CMAJ. 2005 Aug 30;173(5):489-95. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1188185 http://www.ncbi.nlm.nih.gov/pubmed/16129869?tool=bestpractice.com Clinical Frailty Scale Opens in new window
Discuss patients with a high frailty score with the multidisciplinary team.
Establish a treatment escalation plan and record resuscitation status.
Arrange a risk assessment, with input from critical care where necessary.[23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html
benign strictures
initial supportive care
Is the patient stable? Use an Airway, Breathing, Circulation, Disability, Exposure (ABCDE) approach to manage shock empirically.[42]Resuscitation Council (UK). The ABCDE approach. May 2021 [internet publication]. https://www.resus.org.uk/library/abcde-approach Ensure a patent airway and give oxygen if needed.
Treat the underlying cause as early as possible.
Escalate all patients with shock to a senior clinician.
See our topic Shock.
Manage peritonitis with urgent resuscitation and surgery within 6 hours.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide
When peritonitis is related to perforation proximal to a tumour site, patients are at higher risk of developing sepsis compared with patients where the perforation is at the tumour site.[5]Pisano M, Zorcolo L, Merli C, et al. 2017 WSES guidelines on colon and rectal cancer emergencies: obstruction and perforation. World J Emerg Surg. 2018 Aug 13;13:36. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090779 http://www.ncbi.nlm.nih.gov/pubmed/30123315?tool=bestpractice.com
Identify and manage any other complications from bowel obstruction, such as sepsis, urgently.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide See Sepsis in adults.
Practical tip
Sepsis
Think ' Could this be sepsis?' based on acute deterioration in an adult patient in whom there is clinical evidence or strong suspicion of infection.[25]NHS England. Sepsis guidance implementation advice for adults. Sep 2017 [internet publication]. https://www.england.nhs.uk/wp-content/uploads/2017/09/sepsis-guidance-implementation-advice-for-adults.pdf [26]National Institute for Health and Care Excellence. Suspected sepsis: recognition, diagnosis and early management. Mar 2024 [internet publication]. https://www.nice.org.uk/guidance/ng51 [27]Royal College of Physicians. National early warning score (NEWS) 2: standardising the assessment of acute-illness severity in the NHS. Dec 2017 [internet publication]. https://www.rcplondon.ac.uk/projects/outputs/national-early-warning-score-news-2
The patient may present with non-specific or non-localised symptoms (e.g., acutely unwell with a normal temperature) or there may be severe signs with evidence of multi-organ dysfunction and shock.[25]NHS England. Sepsis guidance implementation advice for adults. Sep 2017 [internet publication]. https://www.england.nhs.uk/wp-content/uploads/2017/09/sepsis-guidance-implementation-advice-for-adults.pdf [26]National Institute for Health and Care Excellence. Suspected sepsis: recognition, diagnosis and early management. Mar 2024 [internet publication]. https://www.nice.org.uk/guidance/ng51 [27]Royal College of Physicians. National early warning score (NEWS) 2: standardising the assessment of acute-illness severity in the NHS. Dec 2017 [internet publication]. https://www.rcplondon.ac.uk/projects/outputs/national-early-warning-score-news-2
Remember that sepsis represents the severe, life-threatening end of infection.[30]Inada-Kim M. Introducing the suspicion of sepsis insights dashboard. Royal College of Pathologists Bulletin. 2019 Apr;186;109.
Use a systematic approach (e.g., National Early Warning Score 2 [NEWS2]), alongside your clinical judgement, to assess the risk of deterioration due to sepsis.[25]NHS England. Sepsis guidance implementation advice for adults. Sep 2017 [internet publication]. https://www.england.nhs.uk/wp-content/uploads/2017/09/sepsis-guidance-implementation-advice-for-adults.pdf [26]National Institute for Health and Care Excellence. Suspected sepsis: recognition, diagnosis and early management. Mar 2024 [internet publication]. https://www.nice.org.uk/guidance/ng51 [27]Royal College of Physicians. National early warning score (NEWS) 2: standardising the assessment of acute-illness severity in the NHS. Dec 2017 [internet publication]. https://www.rcplondon.ac.uk/projects/outputs/national-early-warning-score-news-2 [28]Nutbeam T, Daniels R; The UK Sepsis Trust. Professional resources: clinical [internet publication]. https://sepsistrust.org/professional-resources/clinical [31]Evans L, Rhodes A, Alhazzani W, et al. Surviving Sepsis Campaign: international guidelines for management of sepsis and septic shock 2021. Crit Care Med. 2021 Nov 1;49(11):e1063-e143. https://www.doi.org/10.1097/CCM.0000000000005337 http://www.ncbi.nlm.nih.gov/pubmed/34605781?tool=bestpractice.com Consult local guidelines for the recommended approach at your institution.
Arrange urgent review by a senior clinical decision-maker (e.g., ST3 level doctor in the UK) if you suspect sepsis:[29]Academy of Medical Royal Colleges. Statement on the initial antimicrobial treatment of sepsis v2.0. October 2022 [internet publication]. https://www.aomrc.org.uk/reports-guidance/statement-on-the-initial-antimicrobial-treatment-of-sepsis-v2-0
Within 30 minutes for a patient who is critically ill (e.g., NEWS2 score of 7 or more, evidence of septic shock, or other significant clinical concerns)
A patient is also at high risk of severe illness or death from sepsis if they have a NEWS2 score below 7 and a single parameter contributes 3 points to their NEWS2 score and a medical review has confirmed that they are at high risk.
Within 1 hour for a patient who is severely ill (e.g., NEWS2 score of 5 or 6) or within 1 hour of any intervention for suspected sepsis (antibiotics/fluid resuscitation/oxygen) if there is no improvement in the patient’s condition.
Follow your local protocol for investigation and treatment of all patients with suspected sepsis, or those at risk. Start treatment promptly. Determine urgency of treatment according to likelihood of infection and severity of illness, or according to your local protocol.[29]Academy of Medical Royal Colleges. Statement on the initial antimicrobial treatment of sepsis v2.0. October 2022 [internet publication]. https://www.aomrc.org.uk/reports-guidance/statement-on-the-initial-antimicrobial-treatment-of-sepsis-v2-0 [31]Evans L, Rhodes A, Alhazzani W, et al. Surviving Sepsis Campaign: international guidelines for management of sepsis and septic shock 2021. Crit Care Med. 2021 Nov 1;49(11):e1063-e143. https://www.doi.org/10.1097/CCM.0000000000005337 http://www.ncbi.nlm.nih.gov/pubmed/34605781?tool=bestpractice.com
In the community and in custodial settings: refer for emergency medical care in hospital (usually by blue-light ambulance in the UK) any patient who is acutely ill with a suspected infection and is:[26]National Institute for Health and Care Excellence. Suspected sepsis: recognition, diagnosis and early management. Mar 2024 [internet publication]. https://www.nice.org.uk/guidance/ng51
Deemed to be at high risk of deterioration due to organ dysfunction (as measured by risk stratification)
At risk of neutropenic sepsis.
See Sepsis in adults.
Admit to hospital all patients with intestinal obstruction.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html
Treat initially in the accident and emergency department with intravenous fluid resuscitation, nasogastric intubation, and urethral catheterisation.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide Further management depends on the underlying cause of the obstruction. Maintain the patient as nil by mouth.
Fluid management
Measure and document the patient’s hydration status at presentation and throughout the admission.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html Aim to minimise the risk of acute kidney injury.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf See our topic Acute kidney injury.
Use intravenous fluids to treat patients with signs of shock or severe dehydration, or for maintenance in patients unable to tolerate oral fluids.
Indicators that the patient may need urgent fluid resuscitation include:[44]National Institute for Health and Care Excellence. Intravenous fluid therapy in adults in hospital. May 2017 [internet publication]. https://www.nice.org.uk/guidance/cg174
Systolic blood pressure less than 100 mmHg
Heart rate more than 90 beats per minute
Cold peripheries
Capillary refill time more than 2 seconds
Respiratory rate more than 20 breaths per minute
National Early Warning Score (NEWS2) of 5 or more
Passive leg-raising suggests fluid responsiveness.
Check local protocols for specific recommendations on fluid choice.
In patients receiving fluid resuscitation, place a catheter to monitor urine output.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide
Analgesia
Assess pain at presentation and throughout the admission.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html Provide analgesia in line with your local protocol.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html Use opiate analgesia, such as morphine sulphate, for acute abdominal pain.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [45]Manterola C, Vial M, Moraga J, et al. Analgesia in patients with acute abdominal pain. Cochrane Database Syst Rev. 2011 Jan 19;(1):CD005660. https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD005660.pub3/full http://www.ncbi.nlm.nih.gov/pubmed/21249672?tool=bestpractice.com Check your local protocols for specific advice on choice of drugs and doses. Refer to the acute pain team if the patient’s pain is difficult to manage, but ensure that this does not delay definitive treatment.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html
Primary options
morphine sulfate: 5-10 mg subcutaneously/intravenously/intramuscularly every 4 hours initially, adjust dose according to response
These drug options and doses relate to a patient with no comorbidities.
Primary options
morphine sulfate: 5-10 mg subcutaneously/intravenously/intramuscularly every 4 hours initially, adjust dose according to response
Drug choice, dose and interactions may be affected by the patient's comorbidities. Check your local drug formulary.
Show drug information for a patient with no comorbidities
Primary options
morphine sulfate
bowel decompression via nasogastric tube
Additional treatment recommended for SOME patients in selected patient group
Consider decompressing the bowel upstream of the obstruction via a nasogastric tube. This is generally required for patients with a distended small bowel or who are vomiting.
Place a nasogastric tube to decompress air/fluid in the upper gastrointestinal tract.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide This may prevent aerophagia and relieve nausea and vomiting.
Follow your local protocol for this procedure.
Aspirate the tube regularly to reduce the risk of aspiration.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide
Once the obstruction has been resolved, remove the tube as the patient’s clinical condition improves and as nasogastric aspirates decrease.
emergency surgery
Treatment recommended for ALL patients in selected patient group
Emergency surgery is the primary treatment option where perforation or peritonitis is suspected in a patient with volvulus.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [32]Lou Z, Yu ED, Zhang W, et al. Appropriate treatment of acute sigmoid volvulus in the emergency setting. World J Gastroenterol. 2013 Aug 14;19(30):4979-83. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740429 http://www.ncbi.nlm.nih.gov/pubmed/23946604?tool=bestpractice.com
The patient should be under the care of a colorectal surgeon within 24 hours of admission.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html
A consultant review should take place in all patients diagnosed with acute bowel obstruction as soon as clinically indicated and at the latest within 14 hours of admission to hospital.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html
The patient should have their risk of morbidity and mortality assessed and recorded in their medical records by a senior surgeon within 4 hours of admission or transfer.[43]Royal College of Surgeons of England. The high-risk general surgical patient: raising the standard. 2018 [internet publication]. https://www.rcseng.ac.uk/-/media/files/rcs/news-and-events/media-centre/2018-press-releases-documents/rcs-report-the-highrisk-general-surgical-patient--raising-the-standard--december-2018.pdf
Discuss ‘high-risk’ patients with a consultant within 1 hour.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html ‘High risk’ is defined as where the risk of mortality is greater than 10%, or where a patient is unstable and not responding to treatment.[23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html
Consult anaesthetic, critical care, and palliative care teams as well as surgery if needed.[33]NHS Scotland; Health Improvement Scotland. Scottish palliative care guidelines. December 2020 [internet publication]. https://www.palliativecareguidelines.scot.nhs.uk/guidelines/symptom-control/bowel-obstruction.aspx Bowel obstruction can be complex to manage. Multidisciplinary input is needed.[33]NHS Scotland; Health Improvement Scotland. Scottish palliative care guidelines. December 2020 [internet publication]. https://www.palliativecareguidelines.scot.nhs.uk/guidelines/symptom-control/bowel-obstruction.aspx Some hospital trusts offer a service for surgeons to liaise with geriatricians in order to optimise an older patient for surgery and reduce postoperative complications.
The aim of all operations for large bowel obstruction is to restore the flow of the faecal stream and to remove the obstructing lesion, if possible. This is often achieved through the formation of a stoma, either to defunction a downstream obstructing lesion or to avoid the risks inherent to anastomosis.
When deciding whether to make a stoma or form an anastomosis, the surgical team must take into account the severity of the illness and the patient’s condition under anaesthesia.
Bear in mind the morbidity and mortality risks of emergency colonic surgery.
Wherever possible, respect the patient’s wishes with regard to the formation of a stoma.
To treat an obstruction, the three main types of procedure are:
Right hemicolectomy: any operation that removes the ileocaecal valve and the caecum. The colonic resection can be limited to the caecum or extended to the descending colon
Hartmann’s procedure: involves the removal of the sigmoid colon with formation of a left iliac fossa colostomy. The rectal stump is closed. Theoretically reversible, but many patients opt not to undergo another major abdominal operation and, instead, keep their colostomy
Subtotal/total colectomy: carried out for obstructing lesions in the descending or sigmoid colon when the caecum has torn. For these lesions, it is not safe to just remove the obstruction, so subtotal colectomy is undertaken. An ileosigmoid or ileorectal anastomosis can be fashioned if the patient is well enough. Alternatively, an end ileostomy can be formed and the rectal stump oversewn.
Pre-surgical care
Prior to surgery, identify and treat any correctable comorbidities so that surgery is not delayed.
Assess the patient’s bleeding and venous thromboembolism (VTE) risk prior to surgery.[50]National Institute for Health and Care Excellence. Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism. August 2019 [internet publication]. https://www.nice.org.uk/guidance/ng89
Use a validated VTE prophylaxis tool. The National Institute for Health and Care Excellence in the UK states that a commonly used risk assessment tool for surgical patients is the UK Department of Health VTE risk assessment tool.[50]National Institute for Health and Care Excellence. Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism. August 2019 [internet publication]. https://www.nice.org.uk/guidance/ng89 Department of Health VTE risk assessment tool Opens in new window
Follow your local trust protocol for thromboprophylaxis.
Arrange a group and save.
Reassess the risk of bleeding and venous thromboembolism at the point of consultant review or if the patient’s clinical condition changes.
Assess the patient’s risk using appropriate risk prediction tools and your clinical judgement.[23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html [43]Royal College of Surgeons of England. The high-risk general surgical patient: raising the standard. 2018 [internet publication]. https://www.rcseng.ac.uk/-/media/files/rcs/news-and-events/media-centre/2018-press-releases-documents/rcs-report-the-highrisk-general-surgical-patient--raising-the-standard--december-2018.pdf
The patient should have their risk of morbidity and mortality assessed and recorded in their medical records by a senior surgeon within 4 hours of admission or transfer.[43]Royal College of Surgeons of England. The high-risk general surgical patient: raising the standard. 2018 [internet publication]. https://www.rcseng.ac.uk/-/media/files/rcs/news-and-events/media-centre/2018-press-releases-documents/rcs-report-the-highrisk-general-surgical-patient--raising-the-standard--december-2018.pdf
Use a risk score recommended by your local protocol, such as the National Emergency Laparotomy Audit (NELA) risk model in the UK, to calculate a patient’s morbidity and mortality risk before surgery.[23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html [51]Eugene N, Oliver CM, Bassett MG, et al. Development and internal validation of a novel risk adjustment model for adult patients undergoing emergency laparotomy surgery: the National Emergency Laparotomy Audit risk model. Br J Anaesth. 2018 Oct;121(4):739-48. https://bjanaesthesia.org/article/S0007-0912(18)30578-6/fulltext http://www.ncbi.nlm.nih.gov/pubmed/30236236?tool=bestpractice.com
The risk score can be used as a way to explain the risks of surgery to patients and their relatives, which enables shared decision-making and informed consent.
Give antibiotic prophylaxis in line with your local hospital protocol if surgery is needed.[52]National Institute for Health and Care Excellence. Surgical site infections: prevention and treatment. August 2020 [internet publication]. https://www.nice.org.uk/guidance/ng125 This is to reduce the risk of postoperative complications.
screening and monitoring
Treatment recommended for ALL patients in selected patient group
Monitor the patient using an early warning score, such as the National Early Warning Score 2 (NEWS2) score. NEWS2 measures:[27]Royal College of Physicians. National early warning score (NEWS) 2: standardising the assessment of acute-illness severity in the NHS. Dec 2017 [internet publication]. https://www.rcplondon.ac.uk/projects/outputs/national-early-warning-score-news-2 NEWS2 Opens in new window
Respiration rate
Oxygen saturation
Systolic blood pressure
Pulse rate
Level of consciousness or new-onset confusion
Temperature.
Undertake a nutritional screen, such as the Malnutrition Universal Screening Tool (MUST) score, and act on the results.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html [48]National Institute for Health and Care Excellence. Nutrition support for adults: oral nutrition support, enteral tube feeding and parenteral nutrition. August 2017 [internet publication]. https://www.nice.org.uk/guidance/cg32 MUST calculator Opens in new window Provide nutritional support, if indicated.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [48]National Institute for Health and Care Excellence. Nutrition support for adults: oral nutrition support, enteral tube feeding and parenteral nutrition. August 2017 [internet publication]. https://www.nice.org.uk/guidance/cg32 Arrange review by a dietitian or the nutrition team.[23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html Consider nutritional support if the patient has not eaten for 5 days and/or may not be able to resume their usual diet within the next 5 days, or if the patient has a poor absorptive capacity.[48]National Institute for Health and Care Excellence. Nutrition support for adults: oral nutrition support, enteral tube feeding and parenteral nutrition. August 2017 [internet publication]. https://www.nice.org.uk/guidance/cg32
Assess frailty using a score, such as the Rockwood frailty score.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html [49]Rockwood K, Song X, MacKnight C, et al. A global clinical measure of fitness and frailty in elderly people. CMAJ. 2005 Aug 30;173(5):489-95. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1188185 http://www.ncbi.nlm.nih.gov/pubmed/16129869?tool=bestpractice.com Clinical Frailty Scale Opens in new window
Discuss patients with a high frailty score with the multidisciplinary team.
Establish a treatment escalation plan and record resuscitation status.
Arrange a risk assessment, with input from critical care where necessary.[23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html
diverticular disease
initial supportive care
Is the patient stable? Use an Airway, Breathing, Circulation, Disability, Exposure (ABCDE) approach to manage shock empirically.[42]Resuscitation Council (UK). The ABCDE approach. May 2021 [internet publication]. https://www.resus.org.uk/library/abcde-approach Ensure a patent airway and give oxygen if needed.
Treat the underlying cause as early as possible.
Escalate all patients with shock to a senior clinician.
See our topic Shock.
Manage peritonitis with urgent resuscitation and surgery within 6 hours.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide
When peritonitis is related to perforation proximal to a tumour site, patients are at higher risk of developing sepsis compared with patients where the perforation is at the tumour site.[5]Pisano M, Zorcolo L, Merli C, et al. 2017 WSES guidelines on colon and rectal cancer emergencies: obstruction and perforation. World J Emerg Surg. 2018 Aug 13;13:36. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090779 http://www.ncbi.nlm.nih.gov/pubmed/30123315?tool=bestpractice.com
Identify and manage any other complications from bowel obstruction, such as sepsis, urgently.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide See Sepsis in adults.
Practical tip
Sepsis
Think ' Could this be sepsis?' based on acute deterioration in an adult patient in whom there is clinical evidence or strong suspicion of infection.[25]NHS England. Sepsis guidance implementation advice for adults. Sep 2017 [internet publication]. https://www.england.nhs.uk/wp-content/uploads/2017/09/sepsis-guidance-implementation-advice-for-adults.pdf [26]National Institute for Health and Care Excellence. Suspected sepsis: recognition, diagnosis and early management. Mar 2024 [internet publication]. https://www.nice.org.uk/guidance/ng51 [27]Royal College of Physicians. National early warning score (NEWS) 2: standardising the assessment of acute-illness severity in the NHS. Dec 2017 [internet publication]. https://www.rcplondon.ac.uk/projects/outputs/national-early-warning-score-news-2
The patient may present with non-specific or non-localised symptoms (e.g., acutely unwell with a normal temperature) or there may be severe signs with evidence of multi-organ dysfunction and shock.[25]NHS England. Sepsis guidance implementation advice for adults. Sep 2017 [internet publication]. https://www.england.nhs.uk/wp-content/uploads/2017/09/sepsis-guidance-implementation-advice-for-adults.pdf [26]National Institute for Health and Care Excellence. Suspected sepsis: recognition, diagnosis and early management. Mar 2024 [internet publication]. https://www.nice.org.uk/guidance/ng51 [27]Royal College of Physicians. National early warning score (NEWS) 2: standardising the assessment of acute-illness severity in the NHS. Dec 2017 [internet publication]. https://www.rcplondon.ac.uk/projects/outputs/national-early-warning-score-news-2
Remember that sepsis represents the severe, life-threatening end of infection.[30]Inada-Kim M. Introducing the suspicion of sepsis insights dashboard. Royal College of Pathologists Bulletin. 2019 Apr;186;109.
Use a systematic approach (e.g., National Early Warning Score 2 [NEWS2]), alongside your clinical judgement, to assess the risk of deterioration due to sepsis.[25]NHS England. Sepsis guidance implementation advice for adults. Sep 2017 [internet publication]. https://www.england.nhs.uk/wp-content/uploads/2017/09/sepsis-guidance-implementation-advice-for-adults.pdf [26]National Institute for Health and Care Excellence. Suspected sepsis: recognition, diagnosis and early management. Mar 2024 [internet publication]. https://www.nice.org.uk/guidance/ng51 [27]Royal College of Physicians. National early warning score (NEWS) 2: standardising the assessment of acute-illness severity in the NHS. Dec 2017 [internet publication]. https://www.rcplondon.ac.uk/projects/outputs/national-early-warning-score-news-2 [28]Nutbeam T, Daniels R; The UK Sepsis Trust. Professional resources: clinical [internet publication]. https://sepsistrust.org/professional-resources/clinical [31]Evans L, Rhodes A, Alhazzani W, et al. Surviving Sepsis Campaign: international guidelines for management of sepsis and septic shock 2021. Crit Care Med. 2021 Nov 1;49(11):e1063-e143. https://www.doi.org/10.1097/CCM.0000000000005337 http://www.ncbi.nlm.nih.gov/pubmed/34605781?tool=bestpractice.com Consult local guidelines for the recommended approach at your institution.
Arrange urgent review by a senior clinical decision-maker (e.g., ST3 level doctor in the UK) if you suspect sepsis:[29]Academy of Medical Royal Colleges. Statement on the initial antimicrobial treatment of sepsis v2.0. October 2022 [internet publication]. https://www.aomrc.org.uk/reports-guidance/statement-on-the-initial-antimicrobial-treatment-of-sepsis-v2-0
Within 30 minutes for a patient who is critically ill (e.g., NEWS2 score of 7 or more, evidence of septic shock, or other significant clinical concerns)
A patient is also at high risk of severe illness or death from sepsis if they have a NEWS2 score below 7 and a single parameter contributes 3 points to their NEWS2 score and a medical review has confirmed that they are at high risk.
Within 1 hour for a patient who is severely ill (e.g., NEWS2 score of 5 or 6) or within 1 hour of any intervention for suspected sepsis (antibiotics/fluid resuscitation/oxygen) if there is no improvement in the patient’s condition.
Follow your local protocol for investigation and treatment of all patients with suspected sepsis, or those at risk. Start treatment promptly. Determine urgency of treatment according to likelihood of infection and severity of illness, or according to your local protocol.[29]Academy of Medical Royal Colleges. Statement on the initial antimicrobial treatment of sepsis v2.0. October 2022 [internet publication]. https://www.aomrc.org.uk/reports-guidance/statement-on-the-initial-antimicrobial-treatment-of-sepsis-v2-0 [31]Evans L, Rhodes A, Alhazzani W, et al. Surviving Sepsis Campaign: international guidelines for management of sepsis and septic shock 2021. Crit Care Med. 2021 Nov 1;49(11):e1063-e143. https://www.doi.org/10.1097/CCM.0000000000005337 http://www.ncbi.nlm.nih.gov/pubmed/34605781?tool=bestpractice.com
In the community and in custodial settings: refer for emergency medical care in hospital (usually by blue-light ambulance in the UK) any patient who is acutely ill with a suspected infection and is:[26]National Institute for Health and Care Excellence. Suspected sepsis: recognition, diagnosis and early management. Mar 2024 [internet publication]. https://www.nice.org.uk/guidance/ng51
Deemed to be at high risk of deterioration due to organ dysfunction (as measured by risk stratification)
At risk of neutropenic sepsis.
See Sepsis in adults.
Admit to hospital all patients with intestinal obstruction.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html
Treat initially in the accident and emergency department with intravenous fluid resuscitation, nasogastric intubation, and urethral catheterisation.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide Further management depends on the underlying cause of the obstruction. Maintain the patient as nil by mouth.
Fluid management
Measure and document the patient’s hydration status at presentation and throughout the admission.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html Aim to minimise the risk of acute kidney injury.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf See our topic Acute kidney injury.
Use intravenous fluids to treat patients with signs of shock or severe dehydration, or for maintenance in patients unable to tolerate oral fluids.
Indicators that the patient may need urgent fluid resuscitation include:[44]National Institute for Health and Care Excellence. Intravenous fluid therapy in adults in hospital. May 2017 [internet publication]. https://www.nice.org.uk/guidance/cg174
Systolic blood pressure less than 100 mmHg
Heart rate more than 90 beats per minute
Cold peripheries
Capillary refill time more than 2 seconds
Respiratory rate more than 20 breaths per minute
National Early Warning Score (NEWS2) of 5 or more
Passive leg-raising suggests fluid responsiveness.
Check local protocols for specific recommendations on fluid choice.
In patients receiving fluid resuscitation, place a catheter to monitor urine output.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide
Analgesia
Assess pain at presentation and throughout the admission.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html Provide analgesia in line with your local protocol.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html Use opiate analgesia, such as morphine sulphate, for acute abdominal pain.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [45]Manterola C, Vial M, Moraga J, et al. Analgesia in patients with acute abdominal pain. Cochrane Database Syst Rev. 2011 Jan 19;(1):CD005660. https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD005660.pub3/full http://www.ncbi.nlm.nih.gov/pubmed/21249672?tool=bestpractice.com Check your local protocols for specific advice on choice of drugs and doses. Refer to the acute pain team if the patient’s pain is difficult to manage, but ensure that this does not delay definitive treatment.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html
Primary options
morphine sulfate: 5-10 mg subcutaneously/intravenously/intramuscularly every 4 hours initially, adjust dose according to response
These drug options and doses relate to a patient with no comorbidities.
Primary options
morphine sulfate: 5-10 mg subcutaneously/intravenously/intramuscularly every 4 hours initially, adjust dose according to response
Drug choice, dose and interactions may be affected by the patient's comorbidities. Check your local drug formulary.
Show drug information for a patient with no comorbidities
Primary options
morphine sulfate
medical management
Additional treatment recommended for SOME patients in selected patient group
Use medical management for uncomplicated disease.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide
Admit the patient for intravenous antibiotics and fluids.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide
In a patient with mild disease, consider management in an emergency ambulatory setting, where service provision allows, and providing real-time imaging and senior clinical input are available. In this setting, treat with oral antibiotics, fluids, and stool softeners. Review the patient regularly.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide
See our topic Diverticular disease.
emergency surgery
Additional treatment recommended for SOME patients in selected patient group
Complications requiring further investigation and treatment include bleeding, abscess, obstruction, perforation, and fistulae. The presence of complications warrants a surgical consultation.
The options for treatment for patients with complicated disease or who fail to respond to conservative treatment need to be decided on an individual basis.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide Treatment options include: emergency surgery, laparoscopic lavage, and abscess drainage.
See our topic Diverticular disease.
Urgent surgery may be required.
The patient should be under the care of a colorectal surgeon within 24 hours of admission.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html
A consultant review should take place in all patients diagnosed with acute bowel obstruction as soon as clinically indicated and at the latest within 14 hours of admission to hospital.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html
The patient should have their risk of morbidity and mortality assessed and recorded in their medical records by a senior surgeon within 4 hours of admission or transfer.[43]Royal College of Surgeons of England. The high-risk general surgical patient: raising the standard. 2018 [internet publication]. https://www.rcseng.ac.uk/-/media/files/rcs/news-and-events/media-centre/2018-press-releases-documents/rcs-report-the-highrisk-general-surgical-patient--raising-the-standard--december-2018.pdf
Discuss ‘high-risk’ patients with a consultant within 1 hour.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html ‘High risk’ is defined as where the risk of mortality is greater than 10%, or where a patient is unstable and not responding to treatment.[23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html
Consult anaesthetic, critical care, and palliative care teams as well as surgery if needed.[33]NHS Scotland; Health Improvement Scotland. Scottish palliative care guidelines. December 2020 [internet publication]. https://www.palliativecareguidelines.scot.nhs.uk/guidelines/symptom-control/bowel-obstruction.aspx Bowel obstruction can be complex to manage. Multidisciplinary input is needed.[33]NHS Scotland; Health Improvement Scotland. Scottish palliative care guidelines. December 2020 [internet publication]. https://www.palliativecareguidelines.scot.nhs.uk/guidelines/symptom-control/bowel-obstruction.aspx Some hospital trusts offer a service for surgeons to liaise with geriatricians in order to optimise an older patient for surgery and reduce postoperative complications.
Pre-surgical care
Prior to surgery, identify and treat any correctable comorbidities so that surgery is not delayed.
Assess the patient’s bleeding and venous thromboembolism (VTE) risk prior to surgery.[50]National Institute for Health and Care Excellence. Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism. August 2019 [internet publication]. https://www.nice.org.uk/guidance/ng89
Use a validated VTE prophylaxis tool. The National Institute for Health and Care Excellence in the UK states that a commonly used risk assessment tool for surgical patients is the UK Department of Health VTE risk assessment tool.[50]National Institute for Health and Care Excellence. Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism. August 2019 [internet publication]. https://www.nice.org.uk/guidance/ng89 Department of Health VTE risk assessment tool Opens in new window
Follow your local trust protocol for thromboprophylaxis.
Arrange a group and save.
Reassess the risk of bleeding and venous thromboembolism at the point of consultant review or if the patient’s clinical condition changes.
Assess the patient’s risk using appropriate risk prediction tools and your clinical judgement.[23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html [43]Royal College of Surgeons of England. The high-risk general surgical patient: raising the standard. 2018 [internet publication]. https://www.rcseng.ac.uk/-/media/files/rcs/news-and-events/media-centre/2018-press-releases-documents/rcs-report-the-highrisk-general-surgical-patient--raising-the-standard--december-2018.pdf
The patient should have their risk of morbidity and mortality assessed and recorded in their medical records by a senior surgeon within 4 hours of admission or transfer.[43]Royal College of Surgeons of England. The high-risk general surgical patient: raising the standard. 2018 [internet publication]. https://www.rcseng.ac.uk/-/media/files/rcs/news-and-events/media-centre/2018-press-releases-documents/rcs-report-the-highrisk-general-surgical-patient--raising-the-standard--december-2018.pdf
Use a risk score recommended by your local protocol, such as the National Emergency Laparotomy Audit (NELA) risk model in the UK, to calculate a patient’s morbidity and mortality risk before surgery.[23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html [51]Eugene N, Oliver CM, Bassett MG, et al. Development and internal validation of a novel risk adjustment model for adult patients undergoing emergency laparotomy surgery: the National Emergency Laparotomy Audit risk model. Br J Anaesth. 2018 Oct;121(4):739-48. https://bjanaesthesia.org/article/S0007-0912(18)30578-6/fulltext http://www.ncbi.nlm.nih.gov/pubmed/30236236?tool=bestpractice.com
The risk score can be used as a way to explain the risks of surgery to patients and their relatives, which enables shared decision-making and informed consent.
Give antibiotic prophylaxis in line with your local hospital protocol if surgery is needed.[52]National Institute for Health and Care Excellence. Surgical site infections: prevention and treatment. August 2020 [internet publication]. https://www.nice.org.uk/guidance/ng125 This is to reduce the risk of postoperative complications.
screening and monitoring
Treatment recommended for ALL patients in selected patient group
Monitor the patient using an early warning score, such as the National Early Warning Score 2 (NEWS2) score. NEWS2 measures:[27]Royal College of Physicians. National early warning score (NEWS) 2: standardising the assessment of acute-illness severity in the NHS. Dec 2017 [internet publication]. https://www.rcplondon.ac.uk/projects/outputs/national-early-warning-score-news-2 NEWS2 Opens in new window
Respiration rate
Oxygen saturation
Systolic blood pressure
Pulse rate
Level of consciousness or new-onset confusion
Temperature.
Undertake a nutritional screen, such as the Malnutrition Universal Screening Tool (MUST) score, and act on the results.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html [48]National Institute for Health and Care Excellence. Nutrition support for adults: oral nutrition support, enteral tube feeding and parenteral nutrition. August 2017 [internet publication]. https://www.nice.org.uk/guidance/cg32 MUST calculator Opens in new window Provide nutritional support, if indicated.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [48]National Institute for Health and Care Excellence. Nutrition support for adults: oral nutrition support, enteral tube feeding and parenteral nutrition. August 2017 [internet publication]. https://www.nice.org.uk/guidance/cg32 Arrange review by a dietitian or the nutrition team.[23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html Consider nutritional support if the patient has not eaten for 5 days and/or may not be able to resume their usual diet within the next 5 days, or if the patient has a poor absorptive capacity.[48]National Institute for Health and Care Excellence. Nutrition support for adults: oral nutrition support, enteral tube feeding and parenteral nutrition. August 2017 [internet publication]. https://www.nice.org.uk/guidance/cg32
Assess frailty using a score, such as the Rockwood frailty score.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html [49]Rockwood K, Song X, MacKnight C, et al. A global clinical measure of fitness and frailty in elderly people. CMAJ. 2005 Aug 30;173(5):489-95. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1188185 http://www.ncbi.nlm.nih.gov/pubmed/16129869?tool=bestpractice.com Clinical Frailty Scale Opens in new window
Discuss patients with a high frailty score with the multidisciplinary team.
Establish a treatment escalation plan and record resuscitation status.
Arrange a risk assessment, with input from critical care where necessary.[23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html
currently receiving palliative care
initial supportive care
Bowel obstruction may occur in patients already receiving palliative care.
Make management decisions with the appropriate multidisciplinary team and involve the patient and/or their carers where possible. Regarding any acute care, consider the patient’s resuscitation status and any agreed ceilings of care in place. If the patient is at the end of life, take treatment and monitoring decisions in accordance with an end of life care pathway.
Is the patient stable? Use an Airway, Breathing, Circulation, Disability, Exposure (ABCDE) approach to manage shock empirically.[42]Resuscitation Council (UK). The ABCDE approach. May 2021 [internet publication]. https://www.resus.org.uk/library/abcde-approach Ensure a patent airway and give oxygen if needed.
Treat the underlying cause as early as possible.
Escalate all patients with shock to a senior clinician.
See our topic Shock.
Standard practice is to manage peritonitis with urgent resuscitation and surgery within 6 hours.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide
When peritonitis is related to perforation proximal to a tumour site, patients are at higher risk of developing sepsis compared with patients where the perforation is at the tumour site.[5]Pisano M, Zorcolo L, Merli C, et al. 2017 WSES guidelines on colon and rectal cancer emergencies: obstruction and perforation. World J Emerg Surg. 2018 Aug 13;13:36. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090779 http://www.ncbi.nlm.nih.gov/pubmed/30123315?tool=bestpractice.com
However, consider whether or not surgery is indicated for the individual patient receiving palliative care. Bear in mind the patient’s condition and their preferences, as well as the benefits and risks when considering surgery.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide
Factors that may suggest surgery is not indicated:[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [55]Binet Q, Duck L. Management of end-stage malignant bowel obstruction: an evidence-based review of clinical practice. Belg J Med Oncol. 2019;13(4):123-8. https://www.ariez.nl/wp-content/uploads/2019/06/BJMO4-2019_Art._Duck_Review-Oncology.pdf
Known diffuse intra-abdominal cancer (seen during surgery or on imaging)
Diffuse, palpable intra-abdominal masses
Massive ascites which recurs rapidly after drainage
High obstruction involving the proximal stomach
Extensive metastatic disease outside the abdomen
Patient with poor performance or nutritional status
Previous radiotherapy to the abdomen or pelvis
Small bowel obstruction at multiple sites.
Identify and manage any other complications from bowel obstruction, such as sepsis, urgently.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide See Sepsis in adults.
Practical tip
Sepsis
Think ' Could this be sepsis?' based on acute deterioration in an adult patient in whom there is clinical evidence or strong suspicion of infection.[25]NHS England. Sepsis guidance implementation advice for adults. Sep 2017 [internet publication]. https://www.england.nhs.uk/wp-content/uploads/2017/09/sepsis-guidance-implementation-advice-for-adults.pdf [26]National Institute for Health and Care Excellence. Suspected sepsis: recognition, diagnosis and early management. Mar 2024 [internet publication]. https://www.nice.org.uk/guidance/ng51 [27]Royal College of Physicians. National early warning score (NEWS) 2: standardising the assessment of acute-illness severity in the NHS. Dec 2017 [internet publication]. https://www.rcplondon.ac.uk/projects/outputs/national-early-warning-score-news-2
The patient may present with non-specific or non-localised symptoms (e.g., acutely unwell with a normal temperature) or there may be severe signs with evidence of multi-organ dysfunction and shock.[25]NHS England. Sepsis guidance implementation advice for adults. Sep 2017 [internet publication]. https://www.england.nhs.uk/wp-content/uploads/2017/09/sepsis-guidance-implementation-advice-for-adults.pdf [26]National Institute for Health and Care Excellence. Suspected sepsis: recognition, diagnosis and early management. Mar 2024 [internet publication]. https://www.nice.org.uk/guidance/ng51 [27]Royal College of Physicians. National early warning score (NEWS) 2: standardising the assessment of acute-illness severity in the NHS. Dec 2017 [internet publication]. https://www.rcplondon.ac.uk/projects/outputs/national-early-warning-score-news-2
Remember that sepsis represents the severe, life-threatening end of infection.[30]Inada-Kim M. Introducing the suspicion of sepsis insights dashboard. Royal College of Pathologists Bulletin. 2019 Apr;186;109.
Use a systematic approach (e.g., National Early Warning Score 2 [NEWS2]), alongside your clinical judgement, to assess the risk of deterioration due to sepsis.[25]NHS England. Sepsis guidance implementation advice for adults. Sep 2017 [internet publication]. https://www.england.nhs.uk/wp-content/uploads/2017/09/sepsis-guidance-implementation-advice-for-adults.pdf [26]National Institute for Health and Care Excellence. Suspected sepsis: recognition, diagnosis and early management. Mar 2024 [internet publication]. https://www.nice.org.uk/guidance/ng51 [27]Royal College of Physicians. National early warning score (NEWS) 2: standardising the assessment of acute-illness severity in the NHS. Dec 2017 [internet publication]. https://www.rcplondon.ac.uk/projects/outputs/national-early-warning-score-news-2 [28]Nutbeam T, Daniels R; The UK Sepsis Trust. Professional resources: clinical [internet publication]. https://sepsistrust.org/professional-resources/clinical [31]Evans L, Rhodes A, Alhazzani W, et al. Surviving Sepsis Campaign: international guidelines for management of sepsis and septic shock 2021. Crit Care Med. 2021 Nov 1;49(11):e1063-e143. https://www.doi.org/10.1097/CCM.0000000000005337 http://www.ncbi.nlm.nih.gov/pubmed/34605781?tool=bestpractice.com Consult local guidelines for the recommended approach at your institution.
Arrange urgent review by a senior clinical decision-maker (e.g., ST4 level doctor in the UK) if you suspect sepsis:[29]Academy of Medical Royal Colleges. Statement on the initial antimicrobial treatment of sepsis v2.0. October 2022 [internet publication]. https://www.aomrc.org.uk/reports-guidance/statement-on-the-initial-antimicrobial-treatment-of-sepsis-v2-0
Within 30 minutes for a patient who is critically ill (e.g., NEWS2 score of 7 or more, evidence of septic shock, or other significant clinical concerns).
A patient is also at high risk of severe illness or death from sepsis if they have a NEWS2 score below 7 and a single parameter contributes 3 points to their NEWS2 score and a medical review has confirmed that they are at high risk.
Within 1 hour for a patient who is severely ill (e.g., NEWS2 score of 5 or 6) or within 1 hour of any intervention for suspected sepsis (antibiotics/fluid resuscitation/oxygen) if there is no improvement in the patient’s condition.
Follow your local protocol for investigation and treatment of all patients with suspected sepsis, or those at risk. Start treatment promptly. Determine urgency of treatment according to likelihood of infection and severity of illness, or according to your local protocol.[29]Academy of Medical Royal Colleges. Statement on the initial antimicrobial treatment of sepsis v2.0. October 2022 [internet publication]. https://www.aomrc.org.uk/reports-guidance/statement-on-the-initial-antimicrobial-treatment-of-sepsis-v2-0 [31]Evans L, Rhodes A, Alhazzani W, et al. Surviving Sepsis Campaign: international guidelines for management of sepsis and septic shock 2021. Crit Care Med. 2021 Nov 1;49(11):e1063-e143. https://www.doi.org/10.1097/CCM.0000000000005337 http://www.ncbi.nlm.nih.gov/pubmed/34605781?tool=bestpractice.com
In the community and in custodial settings: refer for emergency medical care in hospital (usually by blue-light ambulance in the UK) any patient who is acutely ill with a suspected infection and is:[26]National Institute for Health and Care Excellence. Suspected sepsis: recognition, diagnosis and early management. Mar 2024 [internet publication]. https://www.nice.org.uk/guidance/ng51
Deemed to be at high risk of deterioration due to organ dysfunction (as measured by risk stratification)
At risk of neutropenic sepsis.
See Sepsis in adults.
Admit to hospital all patients with intestinal obstruction.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html
Treat initially in the accident and emergency department with intravenous fluid resuscitation, nasogastric intubation, and urethral catheterisation.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide Further management depends on the underlying cause of the obstruction. Maintain the patient as nil by mouth.
Fluid management
Measure and document the patient’s hydration status at presentation and throughout the admission.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html Aim to minimise the risk of acute kidney injury.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf See our topic Acute kidney injury.
Use intravenous fluids to treat patients with signs of shock or severe dehydration, or for maintenance in patients unable to tolerate oral fluids.
Indicators that the patient may need urgent fluid resuscitation include:[44]National Institute for Health and Care Excellence. Intravenous fluid therapy in adults in hospital. May 2017 [internet publication]. https://www.nice.org.uk/guidance/cg174
Systolic blood pressure less than 100 mmHg
Heart rate more than 90 beats per minute
Cold peripheries
Capillary refill time more than 2 seconds
Respiratory rate more than 20 breaths per minute
National Early Warning Score (NEWS2) of 5 or more
Passive leg-raising suggests fluid responsiveness.
Check local protocols for specific recommendations on fluid choice.
In patients receiving fluid resuscitation, place a catheter to monitor urine output.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide
Analgesia
Assess pain at presentation and throughout the admission.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html Provide analgesia in line with your local protocol.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html Use opiate analgesia, such as morphine sulphate, for acute abdominal pain.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [45]Manterola C, Vial M, Moraga J, et al. Analgesia in patients with acute abdominal pain. Cochrane Database Syst Rev. 2011 Jan 19;(1):CD005660. https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD005660.pub3/full http://www.ncbi.nlm.nih.gov/pubmed/21249672?tool=bestpractice.com Check your local protocols for specific advice on choice of drugs and doses. Refer to the acute pain team if the patient’s pain is difficult to manage, but ensure that this does not delay definitive treatment.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html
Primary options
morphine sulfate: 5-10 mg subcutaneously/intravenously/intramuscularly every 4 hours initially, adjust dose according to response
These drug options and doses relate to a patient with no comorbidities.
Primary options
morphine sulfate: 5-10 mg subcutaneously/intravenously/intramuscularly every 4 hours initially, adjust dose according to response
Drug choice, dose and interactions may be affected by the patient's comorbidities. Check your local drug formulary.
Show drug information for a patient with no comorbidities
Primary options
morphine sulfate
emergency surgery
Additional treatment recommended for SOME patients in selected patient group
Bowel obstruction may occur in patients already receiving palliative care.
Make management decisions with the appropriate multidisciplinary team and involve the patient and/or their carers where possible. Regarding any acute care, consider the patient’s resuscitation status and any agreed ceilings of care in place. If the patient is at the end of life, take treatment and monitoring decisions in accordance with an end of life care pathway.
Urgent surgery may be required. However, consider whether or not surgery is indicated for the individual patient receiving palliative care. Bear in mind the patient’s condition and their preferences, as well as the benefits and risks when considering surgery.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide
Factors that may suggest surgery is not indicated:[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide
Known diffuse intra-abdominal cancer (seen during surgery or on imaging)
Diffuse, palpable intra-abdominal masses
Massive ascites which recurs rapidly after drainage
High obstruction involving the proximal stomach
Extensive metastatic disease outside the abdomen
Patient with poor performance or nutritional status
Previous radiotherapy to the abdomen or pelvis
Small bowel obstruction at multiple sites.
Standard practice for the patient having surgery is that:
The patient should be under the care of a colorectal surgeon within 24 hours of admission.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html
A consultant review should take place in all patients diagnosed with acute bowel obstruction as soon as clinically indicated and at the latest within 14 hours of admission to hospital.[3]Association of Surgeons of Great Britain and Ireland; Royal College of Surgeons of England. Commissioning guide: emergency general surgery (acute abdominal pain). Apr 2014 [internet publication]. https://www.rcseng.ac.uk/library-and-publications/rcs-publications/docs/emergency-general-guide [6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html
The patient should have their risk of morbidity and mortality assessed and recorded in their medical records by a senior surgeon within 4 hours of admission or transfer.[43]Royal College of Surgeons of England. The high-risk general surgical patient: raising the standard. 2018 [internet publication]. https://www.rcseng.ac.uk/-/media/files/rcs/news-and-events/media-centre/2018-press-releases-documents/rcs-report-the-highrisk-general-surgical-patient--raising-the-standard--december-2018.pdf
Discuss ‘high-risk’ patients with a consultant within 1 hour.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html ‘High risk’ is defined as where the risk of mortality is greater than 10%, or where a patient is unstable and not responding to treatment.[23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html
Consult anaesthetic, critical care, and palliative care teams as well as surgery if needed.[33]NHS Scotland; Health Improvement Scotland. Scottish palliative care guidelines. December 2020 [internet publication]. https://www.palliativecareguidelines.scot.nhs.uk/guidelines/symptom-control/bowel-obstruction.aspx Bowel obstruction can be complex to manage. Multidisciplinary input is needed.[33]NHS Scotland; Health Improvement Scotland. Scottish palliative care guidelines. December 2020 [internet publication]. https://www.palliativecareguidelines.scot.nhs.uk/guidelines/symptom-control/bowel-obstruction.aspx Some hospital trusts offer a service for surgeons to liaise with geriatricians in order to optimise an older patient for surgery and reduce postoperative complications.
The aim of all operations for large bowel obstruction is to restore the flow of the faecal stream and to remove the obstructing lesion, if possible. This is often achieved through the formation of a stoma, either to defunction a downstream obstructing lesion or to avoid the risks inherent to anastomosis.
When deciding whether to make a stoma or form an anastomosis, the surgical team must take into account the severity of the illness and the patient’s condition under anaesthesia.
Bear in mind the morbidity and mortality risks of emergency colonic surgery.
Wherever possible, respect the patient’s wishes with regard to the formation of a stoma.
To treat an obstruction, the three main types of procedure are:
Right hemicolectomy: any operation that removes the ileocaecal valve and the caecum. The colonic resection can be limited to the caecum or extended to the descending colon
Hartmann’s procedure: involves the removal of the sigmoid colon with formation of a left iliac fossa colostomy. The rectal stump is closed. Theoretically reversible, but many patients opt not to undergo another major abdominal operation and, instead, keep their colostomy
Subtotal/total colectomy: carried out for obstructing lesions in the descending or sigmoid colon when the caecum has torn. For these lesions, it is not safe to just remove the obstruction, so subtotal colectomy is undertaken. An ileosigmoid or ileorectal anastomosis can be fashioned if the patient is well enough. Alternatively, an end ileostomy can be formed and the rectal stump oversewn.
Pre-surgical care
Prior to surgery, identify and treat any correctable comorbidities so that surgery is not delayed.
Assess the patient’s bleeding and venous thromboembolism (VTE) risk prior to surgery.[50]National Institute for Health and Care Excellence. Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism. August 2019 [internet publication]. https://www.nice.org.uk/guidance/ng89
Use a validated VTE prophylaxis tool. The National Institute for Health and Care Excellence in the UK states that a commonly used risk assessment tool for surgical patients is the UK Department of Health VTE risk assessment tool.[50]National Institute for Health and Care Excellence. Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism. August 2019 [internet publication]. https://www.nice.org.uk/guidance/ng89 Department of Health VTE risk assessment tool Opens in new window
Follow your local trust protocol for thromboprophylaxis.
Arrange a group and save.
Reassess the risk of bleeding and venous thromboembolism at the point of consultant review or if the patient’s clinical condition changes.
Assess the patient’s risk using appropriate risk prediction tools and your clinical judgement.[23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html [43]Royal College of Surgeons of England. The high-risk general surgical patient: raising the standard. 2018 [internet publication]. https://www.rcseng.ac.uk/-/media/files/rcs/news-and-events/media-centre/2018-press-releases-documents/rcs-report-the-highrisk-general-surgical-patient--raising-the-standard--december-2018.pdf
The patient should have their risk of morbidity and mortality assessed and recorded in their medical records by a senior surgeon within 4 hours of admission or transfer.[43]Royal College of Surgeons of England. The high-risk general surgical patient: raising the standard. 2018 [internet publication]. https://www.rcseng.ac.uk/-/media/files/rcs/news-and-events/media-centre/2018-press-releases-documents/rcs-report-the-highrisk-general-surgical-patient--raising-the-standard--december-2018.pdf
Use a risk score recommended by your local protocol, such as the National Emergency Laparotomy Audit (NELA) risk model in the UK, to calculate a patient’s morbidity and mortality risk before surgery.[23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html [51]Eugene N, Oliver CM, Bassett MG, et al. Development and internal validation of a novel risk adjustment model for adult patients undergoing emergency laparotomy surgery: the National Emergency Laparotomy Audit risk model. Br J Anaesth. 2018 Oct;121(4):739-48. https://bjanaesthesia.org/article/S0007-0912(18)30578-6/fulltext http://www.ncbi.nlm.nih.gov/pubmed/30236236?tool=bestpractice.com
The risk score can be used as a way to explain the risks of surgery to patients and their relatives, which enables shared decision-making and informed consent.
Give antibiotic prophylaxis in line with your local hospital protocol if surgery is needed.[52]National Institute for Health and Care Excellence. Surgical site infections: prevention and treatment. August 2020 [internet publication]. https://www.nice.org.uk/guidance/ng125 This is to reduce the risk of postoperative complications.
conservative management
Additional treatment recommended for SOME patients in selected patient group
Bowel obstruction may occur in patients already receiving palliative care.
Make management decisions with the appropriate multidisciplinary team and involve the patient and/or their carers where possible. Regarding any acute care, consider the patient’s resuscitation status and any agreed ceilings of care in place. If the patient is at the end of life, take treatment and monitoring decisions in accordance with an end of life care pathway.
If an acute problem, consider conservative management and watchful waiting.[33]NHS Scotland; Health Improvement Scotland. Scottish palliative care guidelines. December 2020 [internet publication]. https://www.palliativecareguidelines.scot.nhs.uk/guidelines/symptom-control/bowel-obstruction.aspx Ensure the patient is nil by mouth in order to rest the bowel. Relieve symptoms with:[33]NHS Scotland; Health Improvement Scotland. Scottish palliative care guidelines. December 2020 [internet publication]. https://www.palliativecareguidelines.scot.nhs.uk/guidelines/symptom-control/bowel-obstruction.aspx [55]Binet Q, Duck L. Management of end-stage malignant bowel obstruction: an evidence-based review of clinical practice. Belg J Med Oncol. 2019;13(4):123-8. https://www.ariez.nl/wp-content/uploads/2019/06/BJMO4-2019_Art._Duck_Review-Oncology.pdf
Laxatives for constipation
A nasogastric tube as a short-term measure to control vomiting
Ice to suck to moisten the mouth and lips, and to manage a sense of thirst.
In a dehydrated patient, use intravenous rehydration initially and subcutaneous rehydration for longer-term management.[33]NHS Scotland; Health Improvement Scotland. Scottish palliative care guidelines. December 2020 [internet publication]. https://www.palliativecareguidelines.scot.nhs.uk/guidelines/symptom-control/bowel-obstruction.aspx [55]Binet Q, Duck L. Management of end-stage malignant bowel obstruction: an evidence-based review of clinical practice. Belg J Med Oncol. 2019;13(4):123-8. https://www.ariez.nl/wp-content/uploads/2019/06/BJMO4-2019_Art._Duck_Review-Oncology.pdf
Consider stenting to treat a localised obstruction in the colon.[33]NHS Scotland; Health Improvement Scotland. Scottish palliative care guidelines. December 2020 [internet publication]. https://www.palliativecareguidelines.scot.nhs.uk/guidelines/symptom-control/bowel-obstruction.aspx [55]Binet Q, Duck L. Management of end-stage malignant bowel obstruction: an evidence-based review of clinical practice. Belg J Med Oncol. 2019;13(4):123-8. https://www.ariez.nl/wp-content/uploads/2019/06/BJMO4-2019_Art._Duck_Review-Oncology.pdf
Treat a mechanical obstruction or an obstruction due to peristaltic failure with medication.
For peristaltic failure:[33]NHS Scotland; Health Improvement Scotland. Scottish palliative care guidelines. December 2020 [internet publication]. https://www.palliativecareguidelines.scot.nhs.uk/guidelines/symptom-control/bowel-obstruction.aspx [55]Binet Q, Duck L. Management of end-stage malignant bowel obstruction: an evidence-based review of clinical practice. Belg J Med Oncol. 2019;13(4):123-8. https://www.ariez.nl/wp-content/uploads/2019/06/BJMO4-2019_Art._Duck_Review-Oncology.pdf
Stop any medications that the patient is taking that reduce peristalsis, such as cyclizine, hyoscine, 5HT3 antagonists, or amitriptyline
Treat constipation with laxatives
Use a prokinetic antiemetic, such as metoclopramide
Stop the medication if colic develops
Use prolonged higher doses with caution and monitor for extrapyramidal side effects
Consider a fentanyl transdermal patch for pain control as it is less constipating than morphine or oxycodone.
For mechanical obstruction:[33]NHS Scotland; Health Improvement Scotland. Scottish palliative care guidelines. December 2020 [internet publication]. https://www.palliativecareguidelines.scot.nhs.uk/guidelines/symptom-control/bowel-obstruction.aspx
Treat constipation with laxatives
Avoid stimulant laxatives if the patient has colic
Stop all laxatives in complete obstruction
Consider parenteral dexamethasone to reverse partial obstruction.
screening and monitoring
Treatment recommended for ALL patients in selected patient group
Bowel obstruction may occur in patients already receiving palliative care.
Make management decisions with the appropriate multidisciplinary team and involve the patient and/or their carers where possible. Regarding any acute care, consider the patient’s resuscitation status and any agreed ceilings of care in place. If the patient is at the end of life, take treatment and monitoring decisions in accordance with an end of life care pathway.
Monitor the patient using an early warning score, such as the National Early Warning Score 2 (NEWS2) score. NEWS2 measures:[27]Royal College of Physicians. National early warning score (NEWS) 2: standardising the assessment of acute-illness severity in the NHS. Dec 2017 [internet publication]. https://www.rcplondon.ac.uk/projects/outputs/national-early-warning-score-news-2 NEWS2 Opens in new window
Respiration rate
Oxygen saturation
Systolic blood pressure
Pulse rate
Level of consciousness or new-onset confusion
Temperature.
Undertake a nutritional screen, such as the Malnutrition Universal Screening Tool (MUST) score, and act on the results.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html [48]National Institute for Health and Care Excellence. Nutrition support for adults: oral nutrition support, enteral tube feeding and parenteral nutrition. August 2017 [internet publication]. https://www.nice.org.uk/guidance/cg32 MUST calculator Opens in new window Provide nutritional support, if indicated.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [48]National Institute for Health and Care Excellence. Nutrition support for adults: oral nutrition support, enteral tube feeding and parenteral nutrition. August 2017 [internet publication]. https://www.nice.org.uk/guidance/cg32 Arrange review by a dietitian or the nutrition team.[23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html Consider nutritional support if the patient has not eaten for 5 days and/or may not be able to resume their usual diet within the next 5 days, or if the patient has a poor absorptive capacity.[48]National Institute for Health and Care Excellence. Nutrition support for adults: oral nutrition support, enteral tube feeding and parenteral nutrition. August 2017 [internet publication]. https://www.nice.org.uk/guidance/cg32
Assess frailty using a score, such as the Rockwood frailty score.[6]The National Confidential Enquiry into Patient Outcome and Death. Delay in transit: a review of the quality of care provided to patients aged over 16 years with a diagnosis of acute bowel obstruction. 2020 [internet publication]. https://www.hqip.org.uk/wp-content/uploads/2020/01/Ref.-93-Med-Surg-Acute-Bowel-Obstruction-Report-FINAL.pdf [23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html [49]Rockwood K, Song X, MacKnight C, et al. A global clinical measure of fitness and frailty in elderly people. CMAJ. 2005 Aug 30;173(5):489-95. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1188185 http://www.ncbi.nlm.nih.gov/pubmed/16129869?tool=bestpractice.com Clinical Frailty Scale Opens in new window
Discuss patients with a high frailty score with the multidisciplinary team.
Establish a treatment escalation plan and record resuscitation status.
Arrange a risk assessment, with input from critical care where necessary.[23]National Confidential Enquiry into Patient Outcome and Death. Acute bowel obstruction: delay in transit. January 2020 [internet publication]. https://www.ncepod.org.uk/2020abo.html
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