Differentials

Pyelonephritis

SIGNS / SYMPTOMS
INVESTIGATIONS
SIGNS / SYMPTOMS

Fever, nausea, and vomiting. On physical examination, flank tenderness is considered pathognomonic for pyelonephritis.

INVESTIGATIONS

Elevated WBC, and positive blood cultures.

Vaginitis

SIGNS / SYMPTOMS
INVESTIGATIONS
SIGNS / SYMPTOMS

Significant pruritus or vaginal discharge.

INVESTIGATIONS

Positive potassium hydroxide (KOH) prep/wet mount and elevated vaginal pH.

Interstitial cystitis

SIGNS / SYMPTOMS
INVESTIGATIONS
SIGNS / SYMPTOMS

Failure to respond to antibiotics.

INVESTIGATIONS

Negative urine cultures.

Chlamydia urethritis

SIGNS / SYMPTOMS
INVESTIGATIONS
SIGNS / SYMPTOMS

Women may experience vaginal discharge. Examination of the cervical os may reveal a cloudy or yellow discharge. Men may have a visible penile discharge.

INVESTIGATIONS

Negative urine culture, positive polymerase chain reaction test for Chlamydia.

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