Case history
Case history #1
A 54-year-old man presents to his primary care physician with a 2-month history of fever, malaise, and weight loss. He also reports frequent epistaxis, abdominal fullness, and early satiety. On examination, he is found to have splenomegaly.
Case history #2
A 50-year-old man presents to his primary care physician for a routine physical examination. He is asymptomatic at the time of the visit and the physical examination is normal. Routine baseline bloods showed elevated WBC and platelet counts.
Other presentations
Less commonly, patients may present with acute gouty arthritis due to excess production of uric acid from extensive cell turnover, bone pain including tenderness of the sternal area due to bone marrow expansion, blurring of vision due to retinal haemorrhages from a high white blood cell count, priapism, or splenic pain due to infarction.[11]
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