The 5-year survival rate is estimated to be 66%.[89]SEER. Cancer stat facts: Soft tissue including heart cancer. 2020 [internet publication].
https://seer.cancer.gov/statfacts/html/soft.html
Factors that affect survival are sex, sarcoma subtype, age, site of involvement, and stage.[90]Pacelli F, Tortorelli AP, Rosa F, et al. Retroperitoneal soft tissue sarcoma: prognostic factors and therapeutic approaches. Tumori. 2008 Jul-Aug;94(4):497-504.
http://www.ncbi.nlm.nih.gov/pubmed/18822685?tool=bestpractice.com
Patients with regional or metastatic soft-tissue sarcoma have a significantly worse outlook, with 5-year survival estimated at 18% and 16%, respectively, compared with 82.6% for those with localised soft-tissue cancer.[89]SEER. Cancer stat facts: Soft tissue including heart cancer. 2020 [internet publication].
https://seer.cancer.gov/statfacts/html/soft.html
Intra-abdominal sarcomas have a poor prognosis, and the majority of patients with retroperitoneal liposarcoma will go on to die of their disease.[91]Levy AD, Manning MA, Al-Refaie WB, et al. Soft-tissue sarcomas of the abdomen and pelvis: Radiologic-pathologic features, part 1-common sarcomas: From the radiologic pathology archives. Radiographics. 2017 Mar-Apr;37(2):462-483.
https://www.doi.org/10.1148/rg.2017160157
http://www.ncbi.nlm.nih.gov/pubmed/28287938?tool=bestpractice.com
Data in older patients are relatively scarce.[92]Lim SM, Yoo CJ, Han JW, et al. Incidence and survival of pediatric soft tissue sarcomas: Comparison between adults and children. Cancer Res Treat. 2015 Jan;47(1):9-17.
https://www.doi.org/10.4143/crt.2013.157
http://www.ncbi.nlm.nih.gov/pubmed/25143049?tool=bestpractice.com