Prognosis

The outcome of colorectal cancer depends on the stage at diagnosis. About half of patients presenting with symptoms have advanced local (stage 3) or metastatic disease (stage 4) at diagnosis.[379][380][381] In contrast, cancers detected by screening are usually at an earlier stage (mostly stage 1-2).[379][380]

In the US, the overall 5-year colorectal cancer survival rate is 65%.[4] The 5-year survival rate is 91.1% for people with localised cancer, 73.7% for people with cancer that has spread to regional lymph nodes, and 15.7% for people with distant metastases at diagnosis.[4] The mortality rate is higher in black people and American Indian/Alaska Native people, and lower in Hispanic people, compared with white people.[4]

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