Primary prevention

Public education may discourage individuals or groups from experimenting with cocaine and other illicit drugs.

In 2020, the US Preventive Services Task Force concluded that there was insufficient evidence to assess the use of primary care-based behavioural counselling interventions to prevent illicit drug use in children, adolescents, and young adults.[26]

Secondary prevention

Because of the risks of cardiovascular disease, people with cocaine use disorder should be advised about changes to diet, physical exercise, weight management, reduction of alcohol consumption, and smoking cessation.

In areas where fentanyl contaminates the cocaine supply, physicians should consider prescribing or distributing naloxone (an opioid antagonist) for people with cocaine use disorder.[27] Fentanyl strips for testing cocaine may also be available to distribute in some areas.

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