Pulmonary tuberculosis

Liver function (aminotransferases, bilirubin, alkaline phosphatase) should be checked at baseline prior to starting therapy. Monthly liver function tests should be obtained in patients with abnormal baseline liver function, underlying liver disease, HIV co-infection, pregnancy, and other risk factors for hepatitis.

Patients on ethambutol are monitored for visual disturbance and, if treated for more than 2 months, will need monthly vision checks. Routine monitoring of renal and liver function may be necessary.

In general, patients should have a chest x-ray at the completion of treatment for pulmonary TB to serve as a new baseline. Otherwise, no routine monitoring after completion of treatment is indicated. In patients with multidrug-resistant TB, close follow-up for 2 years after completion of treatment is recommended (e.g., chest x-ray and sputum collection every 4-6 months).