Venezuelan equine encephalitis virus infection

Celecoxib

One study has demonstrated that celecoxib, a cyclo-oxygenase-2 (COX-2) inhibitor, can reduce upregulation of pro-inflammatory cytokines that can contribute to VEEV-mediated neurological damage following infection in an in vitro model of infection.[43]Risner K, Ahmed A, Bakovic A, et al. Efficacy of FDA-approved anti-inflammatory drugs against venezuelan equine encephalitis virus infection. Viruses. 2019 Dec 12;11(12):1151. https://pmc.ncbi.nlm.nih.gov/articles/PMC6950191 http://www.ncbi.nlm.nih.gov/pubmed/31842327?tool=bestpractice.com ​ In vivo studies are lacking.