Treatment algorithm

Please note that formulations/routes and doses may differ between drug names and brands, drug formularies, or locations. Treatment recommendations are specific to patient groups: see disclaimer

ACUTE

all patients

Back
1st line – 

observation

Early signs of T-2 poisoning will reflect the route of exposure. However, as any route of exposure may lead to systemic symptoms, all patients require observation and monitoring for progression of toxicity over 24 to 48 hours.

Back
Plus – 

supportive care

Treatment recommended for ALL patients in selected patient group

Supportive care is the mainstay of management.

Suspected or confirmed cases of T-2 mycotoxin poisoning should be assessed and monitored for adequacy of airway-protective reflexes (gag and cough), adequacy of oxygenation, and adequacy of ventilation.

Airway control and mechanical ventilation should be considered for any patient with upper airway compromise or a decline in ventilation.

There are no available effective antidotes.

Back
Consider – 

intravenous fluid replacement therapy

Additional treatment recommended for SOME patients in selected patient group

In patients with profuse or intractable vomiting and diarrhoea, aggressive fluid and electrolyte replacement is indicated.

Back
Consider – 

activated charcoal

Additional treatment recommended for SOME patients in selected patient group

Gastrointestinal decontamination with activated charcoal may reduce the absorption of toxins from the stomach and could reduce the severity of poisoning if used soon after ingestion.

Primary options

activated charcoal: consult specialist for guidance on dose

back arrow

Choose a patient group to see our recommendations

Please note that formulations/routes and doses may differ between drug names and brands, drug formularies, or locations. Treatment recommendations are specific to patient groups. See disclaimer

Use of this content is subject to our disclaimer