Prognosis

The prognosis of patients with schizoaffective disorder, measured in terms of overall poor outcome and parameters such as work functioning and cognitive impairments, appears to be better than the prognosis of patients with schizophrenia but worse than the prognosis of patients with mood disorders.[31][39][79][80]

Affective symptoms

Schizoaffective disorder, bipolar type, meaning the presence of manic or mixed episodes, appears to have a better prognosis than the depressive type.

Other prognostic factors

As in schizophrenia, predictors of poor prognosis include an insidious course, prior history of poor functioning, a family history of schizophrenia, predominant psychotic symptoms and negative symptoms, poor recovery in between episodes, mood-incongruent psychotic symptoms, and lack of clear precipitants.[31]

The most important modifiable predictors of outcome are family environment, substance misuse, and duration of untreated psychosis.[17][81][82][83][84]

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