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Last reviewed: 18 Mar 2025
Last updated: 07 Sep 2023

Summary

Definition

History and exam

Key diagnostic factors

  • presence of risk factors
  • motor weakness
  • loss of fine motor co-ordination
  • spasticity
  • paraesthesia, numbness, dysaesthesia
  • hyperreflexia and ankle clonus
  • pathological reflexes
  • contractures
  • loss of perianal sensation, voluntary anal contraction, and anal tone
  • autonomic dysreflexia
  • syrinx

Other diagnostic factors

  • central (midline) pain
  • girdle pain
  • musculoskeletal or visceral pain
  • unsteady gait
  • urinary incontinence or retention
  • constipation
  • sexual dysfunction
  • non-specific malaise
  • radicular pain

Risk factors

  • spinal cord trauma or ischaemia
  • higher-level spinal cord lesion
  • extremes of age
  • narrow spinal canal
  • male sex

Diagnostic investigations

Investigations to consider

  • MRI spine
  • EMG
  • urodynamic studies
  • bladder ultrasound
  • renal ultrasound
  • micturition cysto-urethrogram
  • bone densitometry (DEXA)
  • laboratory evaluation

Treatment algorithm

Contributors

Authors

Cristina Sadowsky, MD

Clinical Director

International Center for Spinal Cord Injury

Kennedy Krieger Institute

Associate Professor Physical Medicine and Rehabilitation

Johns Hopkins School of Medicine

Baltimore

MD

Disclosures

CS is an author of a number of references cited in this topic.

Travis Edmiston, MD

Assistant Professor for Physical Medicine and Rehabilitation

International Center for Spinal Cord Injury

Kennedy Krieger Institute

Baltimore

MD

Disclosures

TE declares that he has no competing interests.

Acknowledgements

Dr Cristina Sadowsky and Dr Travis Edmiston would like to gratefully acknowledge Dr Kenneth Casey and Dr Jwalant Mehta, previous contributors to this topic.

Disclosures

KC and JM declare that they have no competing interests.

Peer reviewers

Steven Kirshblum, MD

Medical Director and Director of Spinal Cord Injury Services

Kessler Institute for Rehabilitation

West Orange

Professor

University of Medicine and Dentistry of New Jersey/New Jersey Medical School

Newark

NJ

Disclosures

SK declares that he has no competing interests.

Deborah Short, MRCP

Consultant in Rehabilitation Medicine

Robert Jones and Agnes Hunt Hospital

Oswestry

UK

Disclosures

DS declares that she has no competing interests.

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