This can be a chronic, disabling condition with elements of fearfulness and behavioural inhibition in childhood. The early recognition and detection of impairments during childhood, coupled with engagement in evidence-based treatment early in life, may offset the trajectory for social anxiety to persist into adulthood. Educational-behavioural interventions directed towards older children/adolescents, parents, school staff, and healthcare providers have been shown to reduce syndromal rates for developing incident social anxiety at 1-year follow-up relative to the control condition.[33]Aune T, Stiles TC. Universal-based prevention of syndromal and subsyndromal social anxiety: a randomized controlled study. J Consult Clin Psychol. 2009 Oct;77(5):867-79.
http://www.ncbi.nlm.nih.gov/pubmed/19803567?tool=bestpractice.com
The beta-blocker propranolol has shown efficacy in single-dose use for focused social anxiety situations, such as performance anxiety, but routine use is not supported in clinical trials.[34]Steenen SA, van Wijk AJ, van der Heijden GJ, et al. Propranolol for the treatment of anxiety disorders: systematic review and meta-analysis. J Psychopharmacol. 2016 Feb;30(2):128-39.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724794
http://www.ncbi.nlm.nih.gov/pubmed/26487439?tool=bestpractice.com
[35]Garakani A, Murrough JW, Freire RC, et al. Pharmacotherapy of anxiety disorders: current and emerging treatment options. Front Psychiatry. 2020 Dec 23:11:595584.
https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2020.595584/full
http://www.ncbi.nlm.nih.gov/pubmed/33424664?tool=bestpractice.com
It is not recommended in generalised social anxiety disorder, as repeated controlled trials have demonstrated no advantage over placebo.[34]Steenen SA, van Wijk AJ, van der Heijden GJ, et al. Propranolol for the treatment of anxiety disorders: systematic review and meta-analysis. J Psychopharmacol. 2016 Feb;30(2):128-39.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724794
http://www.ncbi.nlm.nih.gov/pubmed/26487439?tool=bestpractice.com
[36]Liebowitz, MR, Schneier F, Campeas R, et al. Phenelzine vs atenolol in social phobia. A placebo-controlled comparison. Arch Gen Psychiatry. 1992 Apr;49(4):290-300.
http://www.ncbi.nlm.nih.gov/pubmed/1558463?tool=bestpractice.com
[37]Turner SM, Beidel DC, Jacob RG. Social phobia: a comparison of behavior therapy and atenolol. J Consult Clin Psychol. 1994 Apr;62(2):350-8.
http://www.ncbi.nlm.nih.gov/pubmed/8201073?tool=bestpractice.com
[38]Falloon IR, Lloyd GG, Harpin RE. The treatment of social phobia: real-life rehearsal with nonprofessional therapists. J Nerv Ment Dis. 1981 Mar;169(3):180-4.
http://www.ncbi.nlm.nih.gov/pubmed/7205244?tool=bestpractice.com
[39]Stein MB, Sareen J, Hami S, et al. Pindolol potentiation of paroxetine for generalized social phobia: a double-blind, placebo-controlled, crossover study. Am J Psychiatry. 2001 Oct;158(10):1725-7.
http://www.ncbi.nlm.nih.gov/pubmed/11579011?tool=bestpractice.com