Occupational asthma

Tarlo SM, Balmes J, Balkissoon R, et al. Diagnosis and management of work-related asthma: American College of Chest Physicians Consensus statement. Chest. 2008 Sep;134(3 suppl):1S-41S. Abstract

Baur X, Sigsgaard T, Aasen TB, et al. Guidelines for the management of work-related asthma. Eur Respir J. 2012 Mar;39(3):529-45.Full text  Abstract

Global Initiative for Asthma (GINA). Global strategy for asthma management and prevention. May 2024 [internet publication].Full text

American College of Radiology. ACR appropriateness criteria: occupational lung diseases. 2019 [internet publication].Full text

1. Cullinan P, Vandenplas O, Bernstein D. Assessment and management of occupational asthma. J Allergy Clin Immunol Pract. 2020 Nov-Dec;8(10):3264-75. Abstract

2. Tarlo SM, Lemiere C. Occupational asthma. N Engl J Med. 2014 Feb 13;370(7):640-9. Abstract

3. Malo JL, Vandenplas O. Definitions and classification of work-related asthma. Immunol Allergy Clin North Am. 2011 Nov;31(4):645-62. Abstract

4. Vandenplas O, Wiszniewska M, Raulf M, et al. EAACI position paper: irritant-induced asthma. Allergy. 2014 Sep;69(9):1141-53.Full text  Abstract

5. Murgia N, Akgun M, Blanc PD, et al. Issue 3-the occupational burden of respiratory diseases, an update. Pulmonology. 2025 Dec 31;31(1):2416808.Full text  Abstract

6. Mazurek JM, Knoeller GE, Moorman JE, et al. Occupational asthma incidence: findings from the behavioral risk factor surveillance system asthma call-back survey--United States, 2006-2009. J Asthma. 2013 May;50(4):390-4. Abstract

7. Mapp CE, Boschetto P, Maestrelli P, et al. Occupational asthma. Am J Respir Crit Care Med. 2005 Aug 1;172(3):280-305.Full text  Abstract

8. McDonald JC, Chen Y, Zekveld C, et al. Incidence by occupation and industry of acute work related respiratory diseases in the UK, 1992-2001. Occup Environ Med. 2005 Dec;62(12):836-42. Abstract

9. Kogevinas M, Zock JP, Jarvis D, et al. Exposure to substances in the workplace and new-onset asthma: an international prospective population-based study (ECRHS-II). Lancet. 2007 Jul 28;370(9584):336-41. Abstract

10. Karjalainen A, Kurppa K, Martikainen R, et al. Work is related to a substantial portion of adult-onset asthma incidence in the Finnish population. Am J Respir Crit Care Med. 2001 Aug 15;164(4):565-8. Abstract

11. Torén K, Blanc PD. Asthma caused by occupational exposures is common: a systematic analysis of estimates of the population-attributable fraction. BMC Pulm Med. 2009 Jan 29:9:7.Full text  Abstract

12. Jeebhay MF, Quirce S. Occupational asthma in the developing and industrialised world: a review. Int J Tuberc Lung Dis. 2007 Feb;11(2):122-33.Full text  Abstract

13. Syabbalo N. Occupational asthma in a developing country. Chest. 1991 Feb;99(2):528.Full text  Abstract

14. Stocks SJ, McNamee R, van der Molen HF, et al. Trends in incidence of occupational asthma, contact dermatitis, noise-induced hearing loss, carpal tunnel syndrome and upper limb musculoskeletal disorders in European countries from 2000 to 2012. Occup Environ Med. 2015 Apr;72(4):294-303.Full text  Abstract

15. Seed MJ, Carder M, Gittins M, et al. Emerging trends in the UK incidence of occupational asthma: should we be worried? Occup Environ Med. 2019 Jun;76(6):396-7. Abstract

16. Wai Y, Tarlo SM. Occupational lung disease in women. In: Buist S, Mapp CE, ed.Respiratory diseases in women. European Respiratory Monograph, vol 8, no 25.Lausanne, Switzerland: European Respiratory Society; 2003:131-46.

17. Gautrin D, Infante-Rivard C, Ghezzo H, et al. Incidence and host determinants of probable occupational asthma in apprentices exposed to laboratory animals. Am J Respir Crit Care Med. 2001 Mar;163(4):899-904.Full text  Abstract

18. Vizcaya D, Mirabelli MC, Gimeno D, et al. Cleaning products and short-term respiratory effects among female cleaners with asthma. Occup Environ Med. 2015 Nov;72(11):757-63. Abstract

19. Macan J, Babić Ž, Hallmann S, et al. Respiratory toxicity of persulphate salts and their adverse effects on airways in hairdressers: a systematic review. Int Arch Occup Environ Health. 2022 Oct;95(8):1679-702.Full text  Abstract

20. Garrido AN, House R, Lipszyc JC, et al. Cleaning agent usage in healthcare professionals and relationship to lung and skin symptoms. J Asthma. 2022 Apr;59(4):673-81. Abstract

21. Mwanga HH, Baatjies R, Jeebhay MF. Occupational risk factors and exposure-response relationships for airway disease among health workers exposed to cleaning agents in tertiary hospitals. Occup Environ Med. 2023 Jul;80(7):361-71.Full text  Abstract

22. Barber CM, Cullinan P, Feary J, et al. British Thoracic Society clinical statement on occupational asthma. Thorax. 2022 May;77(5):433-42.Full text  Abstract

23. Baur X, Bakehe P. Allergens causing occupational asthma: an evidence-based evaluation of the literature. Int Arch Occup Environ Health. 2014 May;87(4):339-63.Full text  Abstract

24. Cartier A. New causes of immunologic occupational asthma, 2012-2014. Curr Opin Allergy Clin Immunol. 2015 Apr;15(2):117-23. Abstract

25. Tarlo SM, Liss GM. Occupational asthma: an approach to diagnosis and management. CMAJ. 2003 Apr 1;168(7):867-71.Full text  Abstract

26. Fishwick D, Carder M, Iskandar I, et al. Irritant asthma and work: cases from the UK SWORD reporting scheme from 1999 to 2018. Occup Environ Med. 2023 Oct;80(10):553-7.Full text  Abstract

27. Tarlo SM, Liss GM, Yeung KS. Changes in rates and severity of compensation claims for asthma due to diisocyanates: a possible effect of medical surveillance measures. Occup Environ Med. 2002 Jan;59(1):58-62.Full text  Abstract

28. Le Moual N, Kennedy SM, Kauffmann F. Occupational exposures and asthma in 14,000 adults from the general population. Am J Epidemiol. 2004 Dec 1;160(11):1108-16.Full text  Abstract

29. Vandenplas O, Godet J, Hurdubaea L, et al. Are high- and low-molecular-weight sensitizing agents associated with different clinical phenotypes of occupational asthma? Allergy. 2019 Feb;74(2):261-72. Abstract

30. Malo JL, Ghezzo H, D'Aquino C, et al. Natural history of occupational asthma: relevance of type of agent and other factors in the rate of development of symptoms in affected subjects. J Allergy Clin Immunol. 1992 Dec;90(6 pt 1):937-44. Abstract

31. Weaver VM, Hua JT, Fitzsimmons KM, et al. Fatal occupational asthma in cannabis production - Massachusetts, 2022. MMWR Morb Mortal Wkly Rep. 2023 Nov 17;72(46):1257-61.Full text  Abstract

32. Decuyper II, Green BJ, Sussman GL, et al. Occupational allergies to cannabis. J Allergy Clin Immunol Pract. 2020 Nov-Dec;8(10):3331-8.Full text  Abstract

33. Lindström I, Lantto J, Karvala K, et al. Occupations and exposure events in acute and subacute irritant-induced asthma. Occup Environ Med. 2021 Nov;78(11):793-800.Full text  Abstract

34. Yucesoy B, Kaufman KM, Lummus ZL, et al. Genome-wide association study identifies novel loci associated with diisocyanate-induced occupational asthma. Toxicol Sci. 2015 Jul;146(1):192-201.Full text  Abstract

35. Word LJ, McAden EP, Poole C, et al. The genetics of occupational asthma development among workers exposed to diisocyanates: a systematic literature review with meta-analysis. Front Genet. 2022 Oct 6:13:944197.Full text  Abstract

36. Tarlo SM, Balmes J, Balkissoon R, et al. Diagnosis and management of work-related asthma: American College of Chest Physicians Consensus statement. Chest. 2008 Sep;134(3 suppl):1S-41S. Abstract

37. Doyen V, Migueres N, Frère A, et al. Diagnostic accuracy of specific IgE against wheat and rye in flour-induced occupational asthma. J Allergy Clin Immunol Pract. 2024 Aug;12(8):2017-25.e5. Abstract

38. Sastre J, Vandenplas O, Park HS. Pathogenesis of occupational asthma. Eur Respir J. 2003 Aug;22(2):364-73.Full text  Abstract

39. Lummus ZL, Alam R, Bernstein JA, et al. Diisocyanate antigen-enhanced production of monocyte chemoattractant protein-1, IL-8, and tumor necrosis factor-alpha by peripheral mononuclear cells of workers with occupational asthma. J Allergy Clin Immunol. 1998 Aug;102(2):265-74. Abstract

40. Dumas O, Laurent E, Bousquet J, et al. Occupational irritants and asthma: an Estonian cross-sectional study of 34,000 adults. Eur Respir J. 2014 Sep;44(3):647-56. Abstract

41. Lemière C, D'Alpaos V, Chaboillez S, et al. Investigation of occupational asthma: sputum cell counts or exhaled nitric oxide? Chest. 2010 Mar;137(3):617-22. Abstract

42. Girard F, Chaboillez S, Cartier A, et al. An effective strategy for diagnosing occupational asthma: use of induced sputum. Am J Respir Crit Care Med. 2004 Oct 15;170(8):845-50. Abstract

43. Quirce S. Eosinophilic bronchitis in the workplace. Curr Opin Allergy Clin Immunol. 2004 Apr;4(2):87-91. Abstract

44. Lemiere C, Lavoie G, Doyen V, et al. Irritant-induced asthma. J Allergy Clin Immunol Pract. 2022 Nov;10(11):2799-806. Abstract

45. Andrianjafimasy MV, Febrissy M, Zerimech F, et al. Association between occupational exposure to irritant agents and a distinct asthma endotype in adults. Occup Environ Med. 2022 Mar;79(3):155-61.Full text  Abstract

46. Vandenplas O. Occupational asthma: etiologies and risk factors. Allergy Asthma Immunol Res. 2011 Jul;3(3):157-67.Full text  Abstract

47. Maestrelli P, Schlünssen V, Mason P, et al. Contribution of host factors and workplace exposure to the outcome of occupational asthma. Eur Respir Rev. 2012 Jun 1;21(124):88-96.Full text  Abstract

48. Taylor AN. Role of human leukocyte antigen phenotype and exposure in development of occupational asthma. Curr Opin Allergy Clin Immunol. 2001 Apr;1(2):157-61. Abstract

49. Taylor AJ. HLA phenotype and exposure in development of occupational asthma. Ann Allergy Asthma Immunol. 2003 May;90(5 suppl 2):24-7. Abstract

50. Choi JH, Lee KW, Kim CW, et al. The HLA DRB1*1501-DQB1*0602-DPB1*0501 haplotype is a risk factor for toluene diisocyanate-induced occupational asthma. Int Arch Allergy Immunol. 2009;150(2):156-63. Abstract

51. Siracusa A, Marabini A, Folletti I, et al. Smoking and occupational asthma. Clin Exp Allergy. 2006 May;36(5):577-84. Abstract

52. Baur X, Sigsgaard T, Aasen TB, et al. Guidelines for the management of work-related asthma. Eur Respir J. 2012 Mar;39(3):529-45.Full text  Abstract

53. Hoy R, Burdon J, Chen L, et al. Work-related asthma: a position paper from the Thoracic Society of Australia and New Zealand and the National Asthma Council Australia. Respirology. 2020 Nov;25(11):1183-92.Full text  Abstract

54. Ribeiro M, Tarlo SM, Czyrka A, et al. Diisocyanate and non-diisocyanate sensitizer-induced occupational asthma frequency during 2003 to 2007 in Ontario, Canada. J Occup Environ Med. 2014 Sep;56(9):1001-7. Abstract

55. Baur X. Are we closer to developing threshold limit values for allergens in the workplace? Ann Allergy Asthma Immunol. 2003 May;90(5 suppl 2):11-8. Abstract

56. Baatjies R, Meijster T, Heederik D, et al. Effectiveness of interventions to reduce flour dust exposures in supermarket bakeries in South Africa. Occup Environ Med. 2014 Dec;71(12):811-8. Abstract

57. Global Initiative for Asthma (GINA). Global strategy for asthma management and prevention. May 2024 [internet publication].Full text

58. British Thoracic Society; National Institute for Health and Care Excellence; Scottish Intercollegiate Guidelines Network. Asthma: diagnosis, monitoring and chronic asthma management (BTS, NICE, SIGN). Nov 2024 [internet publication].Full text

59. British Thoracic Society; National Institute for Health and Care Excellence; Scottish Intercollegiate Guidelines Network. Asthma pathway (BTS, NICE, SIGN). Nov 2024 [internet publication].Full text

60. Pellegrino R, Viegi G, Brusasco V, et al. Interpretative strategies for lung function tests. Eur Respir J. 2005 Nov;26(5):948-68.Full text  Abstract

61. Crapo RO, Casaburi R, Coates AL, et al. American Thoracic Society: guidelines for methacholine and exercise challenge testing - 1999. Am J Respir Crit Care Med. 2000 Jan;161(1):309-29. Abstract

62. American College of Radiology. ACR appropriateness criteria: occupational lung diseases. 2019 [internet publication].Full text

63. Baur X. A compendium of causative agents of occupational asthma. J Occup Med Toxicol. 2013 May 24;8(1):15.Full text  Abstract

64. Raulf M, Buters J, Chapman M, et al. Monitoring of occupational and environmental aeroallergens-- EAACI position paper. Concerted action of the EAACI IG Occupational Allergy and Aerobiology & Air Pollution. Allergy. 2014 Oct;69(10):1280-99.Full text  Abstract

65. Rosenman KD, Beckett WS. Web based listing of agents associated with new onset work-related asthma. Respir Med. 2015 May;109(5):625-31. Abstract

66. Beach J, Russell K, Blitz S, et al. A systematic review of the diagnosis of occupational asthma. Chest. 2007 Feb;131(2):569-78. Abstract

67. Vandenplas O, Suojalehto H, Aasen TB, et al. Specific inhalation challenge in the diagnosis of occupational asthma: consensus statement. Eur Respir J. 2014 Jun;43(6):1573-87.Full text  Abstract

68. Beach J, Rowe BH, Blitz S, et al. Diagnosis and management of work-related asthma. Evid Rep Technol Assess (Summ). 2005 Oct:(129):1-8.Full text  Abstract

69. Liss GM, Tarlo SM. Peak expiratory flow rates in possible occupational asthma. Chest. 1991 Jul;100(1):63-9. Abstract

70. Perrin B, Lagier F, L'Archevêque J, et al. Occupational asthma: validity of monitoring of peak expiratory flow rates and non-allergic bronchial responsiveness as compared to specific inhalation challenge. Eur Respir J. 1992 Jan;5(1):40-8. Abstract

71. American College of Occupational and Environmental Medicine. Guidance and position statements: Work-related asthma. May 2015 [internet publication].Full text

72. Côté J, Kennedy S, Chan-Yeung M. Sensitivity and specificity of PC20 and peak expiratory flow rate in cedar asthma. J Allergy Clin Immunol. 1990 Mar;85(3):592-8. Abstract

73. Pralong JA, Lemière C, Rochat T, et al. Predictive value of nonspecific bronchial responsiveness in occupational asthma. J Allergy Clin Immunol. 2016 Feb;137(2):412-6. Abstract

74. Vandenplas O, Ghezzo H, Munoz X, et al. What are the questionnaire items most useful in identifying subjects with occupational asthma? Eur Respir J. 2005 Dec;26(6):1056-63.Full text  Abstract

75. Malo JL, Ghezzo H, L'Archeveque J, et al. Is the clinical history a satisfactory means of diagnosing occupational asthma? Am Rev Respir Dis. 1991 Mar;143(3):528-32. Abstract

76. Stanojevic S, Kaminsky DA, Miller MR, et al. ERS/ATS technical standard on interpretive strategies for routine lung function tests. Eur Respir J. 2022 Jul;60(1):2101499.Full text  Abstract

77. Chan-Yeung M, Malo JL, Tarlo SM, et al. Proceedings of the first Jack Pepys Occupational Asthma Symposium. Am J Respir Crit Care Med. 2003 Feb 1;167(3):450-71. Abstract

78. Lux H, Lenz K, Budnik LT, et al. Performance of specific immunoglobulin E tests for diagnosing occupational asthma: a systematic review and meta-analysis. Occup Environ Med. 2019 Apr;76(4):269-78. Abstract

79. Nicholson PJ, Cullinan P, Burge PS, et al. Occupational asthma: prevention, identification & management: systematic review & recommendations. London: British Occupational Health Research Foundation; 2010.Full text

80. Vandenplas O, Malo JL. Inhalation challenges with agents causing occupational asthma. Eur Respir J. 1997 Nov;10(11):2612-29.Full text  Abstract

81. Louis R, Satia I, Ojanguren I, et al. European Respiratory Society guidelines for the diagnosis of asthma in adults. Eur Respir J. 2022 Feb 15:2101585.Full text  Abstract

82. Piipari R, Piirilä P, Keskinen H, et al. Exhaled nitric oxide in specific challenge tests to assess occupational asthma. Eur Respir J. 2002 Dec;20(6):1532-7.Full text  Abstract

83. Oțelea MR, Fell AKM, Handra CM, et al. The value of fractional exhaled nitric oxide in occupational diseases - a systematic review. J Occup Med Toxicol. 2022 Jul 25;17(1):14.Full text  Abstract

84. Gibson PG, Fujimura M, Niimi A. Eosinophilic bronchitis: clinical manifestations and implications for treatment. Thorax. 2002 Feb;57(2):178-82.Full text  Abstract

85. Fishwick D, Bradshaw L, Henson M, et al. Occupational asthma: an assessment of diagnostic agreement between physicians. Occup Environ Med. 2007 Mar;64(3):185-90. Abstract

86. Balmes J, Becklake M, Blanc P, et al. American Thoracic Society Statement: occupational contribution to the burden of airway disease. Am J Respir Crit Care Med. 2003 Mar 1;167(5):787-97. Abstract

87. Andrianopoulos MV, Gallivan GJ, Gallivan KH. PVCM, PVCD, EPL, and irritable larynx syndrome: what are we talking about and how do we treat it? J Voice. 2000 Dec;14(4):607-18. Abstract

88. Vlahakis NE, Patel AM, Maragos NE, et al. Diagnosis of vocal cord dysfunction: the utility of spirometry and plethysmography. Chest. 2002 Dec;122(6):2246-9. Abstract

89. Vandenplas O, Dressel H, Nowak D, et al. What is the optimal management option for occupational asthma? Eur Respir Rev. 2012 Jun 1;21(124):97-104.Full text  Abstract

90. Henneberger PK, Patel JR, de Groene GJ, et al. Workplace interventions for treatment of occupational asthma. Cochrane Database Syst Rev. 2019 Oct 8;10(10):CD006308.Full text  Abstract

91. Ameille J, Descatha A. Outcome of occupational asthma. Curr Opin Allergy Clin Immunol. 2005 Apr;5(2):125-8. Abstract

92. Vandenplas O, Henneberger PK. Socioeconomic outcomes in work-exacerbated asthma. Curr Opin Allergy Clin Immunol. 2007 Jun;7(3):236-41. Abstract

93. Vandenplas O, Dressel H, Wilken D, et al. Management of occupational asthma: cessation or reduction of exposure? A systematic review of available evidence. Eur Respir J. 2011 Oct;38(4):804-11. Abstract

94. Levy ML, Nicholson PJ. Occupational asthma case finding: a role for primary care. Br J Gen Pract. 2004 Oct;54(507):731-3.Full text  Abstract

95. Maestrelli P, De Marzo N, Saetta M, et al. Effects of inhaled beclomethasone on airway responsiveness in occupational asthma. Placebo-controlled study of subjects sensitized to toluene diisocyanate. Am Rev Respir Dis. 1993 Aug;148(2):407-12. Abstract

96. Malo JL, Cartier A, Côté J, et al. Influence of inhaled steroids on recovery from occupational asthma after cessation of exposure: an 18-month double-blind crossover study. Am J Respir Crit Care Med. 1996 Mar;153(3):953-60. Abstract

97. Lee JS, Kwak HS, Choi BS, et al. A case of occupational asthma in a plastic injection process worker. Ann Occup Environ Med. 2013 Oct 22;25(1):25.Full text  Abstract

98. Dubini M, Marraccini P, Brass DM, et al. Occupational asthma and rhinitis due to wheat flour: sublingual specific immunotherapy treatment. Med Lav. 2020 Jun 26;111(3):203-9.Full text  Abstract

99. Rachiotis G, Savani R, Brant A, et al. Outcome of occupational asthma after cessation of exposure: a systematic review. Thorax. 2007 Feb;62(2):147-52.Full text  Abstract

100. Brooks SM, Weiss MA, Bernstein IL. Reactive airways dysfunction syndrome (RADS). Persistent asthma syndrome after high level irritant exposures. Chest. 1985 Sep;88(3):376-84. Abstract

101. Lantto J, Suojalehto H, Karvala K, et al. Clinical Characteristics of Irritant-Induced Occupational Asthma. J Allergy Clin Immunol Pract. 2022 Jun;10(6):1554-61.e7.Full text  Abstract

102. Moscato G, Pala G, Boillat MA, et al. EAACI position paper: prevention of work-related respiratory allergies among pre-apprentices or apprentices and young workers. Allergy. 2011 Sep;66(9):1164-73. Abstract

103. Tarlo SM, Malo JL; Fourth Jack Pepys Workshop on Asthma in the Workplace Participants. An official American Thoracic Society proceedings: work-related asthma and airway diseases. Presentations and discussion from the Fourth Jack Pepys Workshop on Asthma in the Workplace. Ann Am Thorac Soc. 2013 Aug;10(4):S17-24.Full text  Abstract

104. Nicholson PJ, Mayho GV, Roomes D, et al. Health surveillance of workers exposed to laboratory animal allergens. Occup Med (Lond). 2010 Dec;60(8):591-7. Abstract