Sudden cardiac death risk associated with ECG parameters in a 10-year follow-up in the Mini-Finland Health Survey
ECG parameter | n (%) | ECG parameters individually | ECG parameters in the same model | ||
HR (95% CI) | P value | HR (95% CI) | P value | ||
Heart rate >80 bpm | 1067 (15.6) | 2.43 (1.65 to 3.58) | <0.001 | 2.19 (1.45 to 3.31) | <0.001 |
PR >220 ms | 143 (2.1) | 3.23 (1.88 to 5.54) | <0.001 | 2.10 (1.20 to 3.68) | 0.010 |
QRS>110 ms | 310 (4.5) | 3.07 (1.94 to 4.86) | <0.001 | 2.05 (1.23 to 3.41) | 0.006 |
Left ventricular hypertrophy | 947 (13.9) | 2.42 (1.66 to 3.52) | <0.001 | 1.73 (1.15 to 2.60) | 0.009 |
T-wave inversion | 328 (4.8) | 4.89 (3.21 to 7.46) | <0.001 | 2.29 (1.29 to 4.08) | 0.005 |
Prolonged QTc | 522 (7.6) | 2.26 (1.46 to 3.51) | <0.001 | 1.27 (0.79 to 2.05) | 0.328 |
Frontal QRS-T angle >90° | 847 (12.4) | 3.14 (2.12 to 4.64) | <0.001 | 1.30 (0.78 to 2.19) | 0.315 |
ST-segment depressions | 336 (4.9) | 4.02 (2.57 to 6.28) | <0.001 | 1.45 (0.85 to 2.46) | 0.176 |
Number of subjects with ECG parameters (% of the total study population). Age-adjusted and sex-adjusted HRs, 95% CIs and p values for SCD risk associated with ECG parameters calculated using the Cox proportional hazards model. Each ECG parameter was first analysed individually and then simultaneously with other ECG parameters in the same model. When analysed individually, early repolarisation pattern, delayed intrinsicoid deflection, delayed QRS transition and T-peak to T-end >90 ms did not associate with an increased risk for SCD, and were excluded from further analysis. Prolonged QTc = QTc over 450 ms in men and over 460 ms in women.
bpm, beats per minute; SCD, sudden cardiac death.