Sensitivity analysis excluding Dar et al:22 Posterior distribution for the HRs relative to usual care (random effects)
| HR and credible interval | Predictive interval | ||||
|---|---|---|---|---|---|
| Outcome variable | Median | 2.5% | 97.5% | 2.5% | 97.5% |
| All-cause mortality* | |||||
| STS HM vs usual care | 0.98 | 0.58 | 1.62 | 0.49 | 1.95 |
| STS HH vs usual care | 0.75 | 0.59 | 0.96 | 0.45 | 1.27 |
| TM office hours† vs usual care | 0.62 | 0.42 | 0.89 | 0.35 | 1.09 |
| TM 24/7‡ vs usual care | 0.49 | 0.26 | 0.88 | 0.23 | 1.04 |
| All-cause hospitalisation§ | |||||
| STS HM vs usual care | 1.06 | 0.48 | 2.32 | 0.35 | 3.22 |
| STS HH vs usual care | 0.96 | 0.72 | 1.27 | 0.42 | 2.18 |
| TM office hours† vs usual care | 0.67 | 0.42 | 0.97 | 0.26 | 1.53 |
| TM 24/7‡ vs usual care | 0.81 | 0.36 | 1.81 | 0.27 | 2.50 |
| HF-related hospitalisation¶ | |||||
| STS HM vs usual care | 1.02 | 0.70 | 1.49 | 0.61 | 1.69 |
| STS HH vs usual care | 0.76 | 0.61 | 0.94 | 0.51 | 1.13 |
| TM office hours† vs usual care | 0.86 | 0.61 | 1.21 | 0.54 | 1.38 |
*All-cause mortality between study SD (log HR scale), 0.14 (95% CrI: 0.01, 0.47).
†Transmitted data reviewed by medical staff (or medical support provided) during office hours.
‡Transmitted data reviewed by medical staff (or medical support provided) 24 hours per day, 7 days per week.
§All-cause hospitalisation between study SD (log HR scale), 0.33 (95% CrI: 0.08, 0.69).
¶Heart failure related hospitalisation between study SD (log HR scale), 0.10 (95% CrI: 0.00, 0.39).
CrI, credible interval; HF, heart failure; HH, human to human contact; HM, human to machine interface; STS, structured telephone support; TM, telemonitoring.