Numbers needed to harm (NNH) or numbers needed to treat (NNT) and numbers of extra or prevented cases, for each outcome over 5 years in patients aged 35–74 free of cardiovascular disease at baseline with QRISK2 score of 20%+ (table reproduced from the BMJ5a)
| NNH or NNT (95% CI) | Estimated number of extra cases (or cases prevented) per 10000 patients treated | |
| Potential benefits in women | ||
| Cardiovascular disease | −37 (−64 to −27) | −271 (−374 to −157) |
| Potential harms in women | ||
| Acute renal failure | 434 (284 to 783) | 23 (13 to 35) |
| Cataract | 33 (28 to 38) | 307 (260 to 355) |
| Liver dysfunction | 136 (109 to 175) | 74 (57 to 91) |
| Myopathy | 259 (186 to 375) | 39 (27 to 54) |
| Potential benefits in men | ||
| Cardiovascular disease | −33 (−57 to −24) | −301 (−417 to −174) |
| Potential harms in men | ||
| Acute renal failure | 346 (245 to 539) | 29 (19 to 41) |
| Cataract | 52 (44 to 63) | 191 (158 to 225) |
| Liver dysfunction | 142 (115 to 180) | 71 (56 to 87) |
| Myopathy | 91 (74 to 112) | 110 (90 to 134) |
Note: negative numbers indicate numbers needed to treat or cases prevented and positive numbers indicate numbers needed to harm or extra cases.