Table 3

Summary of ROC analysis for existing triage tools predicting organ support

Triage tool	n	C-statistic	Cut point	Sensitivity (95% CI)	Specificity (95% CI)	Positive predictive value (95% CI)	Negative predictive value (95% CI)	Proportion test positive
CURB-65	20 716	0.60 (0.59, 0.61)	(>1)	0.52 (0.50 to 0.54)	0.62 (0.61 to 0.63)	0.13 (0.12 to 0.14)	0.92 (0.92 to 0.93)	0.39
CRB-65	20 716	0.58 (0.56, 0.59)	(>0)	0.74 (0.72 to 0.76)	0.42 (0.41 to 0.42)	0.12 (0.12 to 0.13)	0.94 (0.93 to 0.94)	0.60
PMEWS	20 492	0.68 (0.67, 0.69)	(>2)	0.94 (0.93 to 0.95)	0.27 (0.26 to 0.27)	0.12 (0.12 to 0.13)	0.98 (0.97 to 0.98)	0.76
NEWS2 (score)	20 594	0.72 (0.71, 0.73)	(>4)	0.76 (0.74 to 0.78)	0.58 (0.58 to 0.59)	0.17 (0.16 to 0.17)	0.96 (0.95 to 0.96)	0.45
NEWS2 (rule)	20 594	0.65 (0.64, 0.66)	(>0)	0.81 (0.79 to 0.83)	0.49 (0.49 to 0.50)	0.15 (0.14 to 0.16)	0.96 (0.96 to 0.96)	0.54
SFAHP (6-point rule)	19 858	0.64 (0.63, 0.65)	(>0)	0.68 (0.66 to 0.71)	0.60 (0.59 to 0.61)	0.16 (0.15 to 0.17)	0.95 (0.94 to 0.95)	0.43
SFAHP (7-point rule)	20 682	0.65 (0.64, 0.65)	(>0)	0.86 (0.84 to 0.87)	0.43 (0.42 to 0.44)	0.14 (0.14 to 0.15)	0.97 (0.96 to 0.97)	0.60
WHO algorithm	20 891	0.57 (0.57, 0.58)	(>0)	0.91 (0.90 to 0.92)	0.24 (0.23 to 0.24)	0.12 (0.11 to 0.12)	0.96 (0.96 to 0.97)	0.78

NEWS2, National Early Warning Score version 2; PMEWS, Pandemic Modified Early Warning Score; ROC, receiver operating characteristic; SFAHP, swine flu adult hospital pathway.