RT Journal Article SR Electronic T1 PP24 The transient ischaemic attack 999 emergency referral (tier) feasibility trial: development of a complex intervention JF Emergency Medicine Journal JO Emerg Med J FD BMJ Publishing Group Ltd and the British Association for Accident & Emergency Medicine SP e9 OP e9 DO 10.1136/emermed-2017-207114.24 VO 34 IS 10 A1 Rees, Nigel A1 Ali, Khalid A1 Bulger, Jenna A1 Dewar, Richard A1 Edwards, Adrian A1 Evans, Bridie A1 Evans, Lyn A1 Ford, Gary A1 Hampton, Chelsey A1 John, Roger A1 Jones, Charlene A1 Moore, Chris A1 Porter, Alison A1 Pryce, Alan A1 Representative, Lay A1 Quinn, Tom A1 Seagrove, Anne A1 Snooks, Helen A1 Watkins, Alan A1 Whitman, Shirley YR 2017 UL http://emj.bmj.com/content/34/10/e9.1.abstract AB Background Transient Ischaemic Attack (TIA) is a neurologic event with symptom resolution within 24 hours. Early specialist assessment of TIA reduces risk of stroke and death. NICE (2008) recommends patients with TIA are seen in specialist clinics within 24 hours (if high risk) and seven days (if low risk).We aimed to develop a complex intervention for patients with low risk TIA presenting to the emergency ambulance service. The intervention was then to be used in the TIER feasibility trial, in line with the MRC guidance on staged development and evaluation of complex interventions.Methods We conducted three interrelated activities to produce the TIER intervention:Survey of UK Ambulance Services (n=13) to gather information about TIA pathways already in useScoping review of literature describing prehospital care of patients with TIASynthesis of data and definition of the intervention by specialist panel of: paramedics; ED and stroke consultants; service users; ambulance service managers.Results The panel defined the TIER intervention to include:Protocol for paramedics to assess patients presenting with TIA and identify and refer low risk patients for prompt (<7 day) specialist review at TIA clinicPatient Group Directive and information pack to allow paramedic administration of aspirin to patients left at home with referral to TIA clinicReferral process via clinical desk in ambulance control roomTraining package for paramedicsAgreement with TIA clinic service provider to ensure rapid review of referred patientsConclusion We followed MRC guidance to develop a clinical intervention which assesses and refers low risk TIA patients requesting 999 care. We will test feasibility of implementing and evaluating this in the TIER feasibility trial. We will then develop a fully powered randomised multicentre trial, if findings indicate this is appropriate.