Footnotes

• ↵ ⁱ For instance, due to the challenge of possible PERV transmission and PERV activation that could cause deadly human pandemics, which is still daunting in spite of recent attempts at overcoming it using gene editing techniques.6–8 In my own humble opinion, this uncertainty is still the most morally pressing with regard to xenotransplantation, much more pressing that the eventuality of off-target cognitive enhancement of human-pig chimaeric individuals.

• Contributors CM the wrote the entire text.

• Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

• Competing interests None declared.

• Provenance and peer review Not commissioned; internally peer reviewed.

• Patient consent for publication Not required.