Sjögren's Syndrome

Evidence that autoantibody production may be driven by acute Epstein-Barr virus infection in Sjögren’s disease
Erin Hudson, Lijun Yang, Elizabeth K Chu, Haoyang Zhuang, Rawad Daniel Arja, Blas Y Betancourt, Indraneel Bhattacharyya, Shuhong Han, Seunghee Cha, Edward K L Chan, Mathew Sebastian, Carolyn Stalvey, Marvin J Fritzler, Westley H Reeves

Annals of the Rheumatic Diseases Oct 2024, ard-2024-226226; DOI: 10.1136/ard-2024-226226
Dysregulation of immune checkpoint molecules as a characteristic of autoimmune congenital heart block
Ana-Luisa Stefanski, Hector Rincon-Arevalo, Iris Dressler-Steinbach, Nadja Nomovi, Alma Mackert, Arman Aue, Jacob Ritter, Annika Wiedemann, Franziska Szelinski, Eva Schrezenmeier, Anja A Kühl, Andreia C Lino, Wolfgang Henrich, Thomas Dörner

Annals of the Rheumatic Diseases Nov 2024, 83 (11) 1598-1600; DOI: 10.1136/ard-2024-226176
CD8⁺ tissue-resident memory T cells are expanded in primary Sjögren’s disease and can be therapeutically targeted by CD103 blockade
Daniele Mauro, Xiang Lin, Elena Pontarini, Pascale Wehr, Giuliana Guggino, Yuan Tang, Chong Deng, Saviana Gandolfo, Fan Xiao, Ke Rui, Enyu Huang, Jie Tian, Stefania Raimondo, Maureen Rischmueller, Jane Boroky, Sarah Downie-Doyle, Hendrik Nel, Adriana Baz-Morelli, Arthur Hsu, Eugene Maraskovsky, Adele Barr, Patrice Hemon, Loukas Chatzis, Ciro Emiliano Boschetti, Giuseppe Colella, Riccardo Alessandro, Aroldo Rizzo, Jacques-Olivier Pers, Michele Bombardieri, Ranjeny Thomas, Liwei Lu, Francesco Ciccia

Annals of the Rheumatic Diseases Oct 2024, 83 (10) 1345-1357; DOI: 10.1136/ard-2023-225069
m⁶A RNA methylation controls salivary gland epithelial cell function and has a protective role in Sjögren’s disease
Frederic Truffinet, Alejandro Arco-Hierves, Hosnia Shalabi, Juliette Pascaud, Paul Mazet, Elodie Rivière, Sacha E Silva-Saffar, Lucilla Fabbri, Sophie Leboucher, Laetitia Besse, Cedric Messaoudi, Aurore Attina, Alexandre David, Stephan Vagner, Gaetane Nocturne, Xavier Mariette, Rami Bechara

Annals of the Rheumatic Diseases Sep 2024, ard-2024-226224; DOI: 10.1136/ard-2024-226224
Novel autoantibodies help diagnose anti-SSA antibody negative Sjögren disease and predict abnormal labial salivary gland pathology
Maxwell Parker, Zihao Zheng, Michael R Lasarev, Michele C Larsen, Addie Vande Loo, Roxana A Alexandridis, Michael A Newton, Miriam A Shelef, Sara S McCoy

Annals of the Rheumatic Diseases Sep 2024, 83 (9) 1169-1180; DOI: 10.1136/ard-2023-224936
Inhibition of JAK-STAT pathway corrects salivary gland inflammation and interferon driven immune activation in Sjögren’s disease
Sarthak Gupta, Eiko Yamada, Hiroyuki Nakamura, Paola Perez, Thomas JF Pranzatelli, Kalie Dominick, Shyh-Ing Jang, Mehdi Abed, Daniel Martin, Peter Burbelo, ChangYu Zheng, Ben French, Ilias Alevizos, Zohreh Khavandgar, Margaret Beach, Eileen Pelayo, Brian Walitt, Sarfaraz Hasni, Mariana J Kaplan, Mayank Tandon, Maria Teresa Magone, David E Kleiner, John A Chiorini, Alan Baer, Blake M Warner

Annals of the Rheumatic Diseases Aug 2024, 83 (8) 1034-1047; DOI: 10.1136/ard-2023-224842
Efficacy and safety of remibrutinib, a selective potent oral BTK inhibitor, in Sjögren’s syndrome: results from a randomised, double-blind, placebo-controlled phase 2 trial
Thomas Dörner, Martin Kaul, Antónia Szántó, Jui-Cheng Tseng, Athena S Papas, Ilona Pylvaenaeinen, Malika Hanser, Nasri Abdallah, Andrea Grioni, Aida Santos Da Costa, Enrico Ferrero, Peter Gergely, Rainer Hillenbrand, Alexandre Avrameas, Bruno Cenni, Richard M Siegel

Annals of the Rheumatic Diseases Mar 2024, 83 (3) 360-371; DOI: 10.1136/ard-2023-224691
Obinutuzumab in patients with Sjogren’s disease immunised against rituximab
Mathilde Pezot, Gaétane Nocturne, Rakiba Belkhir, Julien Henry, Stephan Pavy, Raphaèle Seror, Xavier Mariette, Samuel Bitoun

Annals of the Rheumatic Diseases Mar 2024, 83 (3) 407-408; DOI: 10.1136/ard-2023-224999
Examining the biological pathways underlying clinical heterogeneity in Sjogren’s syndrome: proteomic and network analysis
Joe Scott Berry, Jessica Tarn, John Casement, Pierre-Marie Duret, Lauren Scott, Karl Wood, Svein-Joar Johnsen, Gunnel Nordmark, Valérie Devauchelle-Pensec, Raphaele Seror, Benjamin Fisher, Fransesca Barone, Simon J Bowman, Michele Bombardieri, Dennis Lendrem, Renaud Felten, Jacques-Eric Gottenberg, Wan-Fai Ng

Annals of the Rheumatic Diseases Jan 2024, 83 (1) 88-95; DOI: 10.1136/ard-2023-224503
Extracting immunological and clinical heterogeneity across autoimmune rheumatic diseases by cohort-wide immunophenotyping
Hiroaki Tanaka, Yukinori Okada, Shingo Nakayamada, Yusuke Miyazaki, Kyuto Sonehara, Shinichi Namba, Suguru Honda, Yuya Shirai, Kenichi Yamamoto, Satoshi Kubo, Katsunori Ikari, Masayoshi Harigai, Koshiro Sonomoto, Yoshiya Tanaka

Annals of the Rheumatic Diseases Feb 2024, 83 (2) 242-252; DOI: 10.1136/ard-2023-224537

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