Table 1

Concerns about vaccination in patients with autoimmune inflammatory rheumatic diseases

Efficacy concernSafety concern

  • Satisfactory vaccine response?

  • Sustained vaccine response?

  • Effect of immunosuppressive treatment on vaccine efficacy and safety?

  • Optimal timing of vaccination?

  • More frequent boosting?

  • Higher vaccine dose?

  • Reactogenicity?

  • Disease flare?

  • Infection from live vaccines?

  • Severe adverse events?

    • Anaphylaxis.

    • Myocarditis.

    • Thrombosis with thrombocytopenia.

    • Guillain-BarrĂ© syndrome.