Patient demographics and baseline clinical characteristics
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*The upper limit of normal for CRP (high sensitivity) was 3 mg/L.
†One patient did not receive methotrexate (not identified until after randomisation), and this was considered a protocol violation.
ACPA, anticitrullinated protein antibody; CRP, C reactive protein; DAS28, Disease Activity Score 28; eow, every other week; ESR, erythrocyte sedimentation rate; HAQ DI, Health Assessment Questionnaire Disability Index; MBDA, multibiomarker disease activity; RA, rheumatoid arthritis; SD, standard deviation; ULN, upper limit of normal.