Distribution of candidate criteria for 125 PMR patients and 169 comparison subjects*
| PMR (N=125) | Comparison subjects (N=169) | p Value | RA (N=49) | p Value | Shoulder conditions† (N=52) | p Value | |
|---|---|---|---|---|---|---|---|
| Age, years, mean±SD | 71.5±8.4 | 67.0±9.6 | <0.001 | 68.6±10.0 | 0.06 | 67.0±10.6 | 0.017 |
| Sex (female) | 72 (58) | 112 (66) | 0.13 | 28 (57) | 0.96 | 35 (67) | 0.23 |
| Duration of symptoms ≥2 weeks | 121 (97) | 163 (96) | 0.87 | 47 (96) | 0.77 | 51 (98) | 0.64 |
| Duration of symptoms, weeks, mean±SD | 10.0±7.2 | 14.4±19.1 | 0.17 | 13.8±16.1 | 0.62 | 12.9±11.8 | 0.21 |
| Bilateral shoulder aching | 124 (99) | 162 (96) | 0.08 | 46 (94) | 0.035 | 50 (96) | 0.15 |
| Bilateral pelvic girdle (hip) aching | 91 (73) | 90 (54) | 0.001 | 28 (57) | 0.046 | 21 (40) | <0.001 |
| Neck aching | 71 (57) | 92 (54) | 0.69 | 29 (59) | 0.78 | 27 (52) | 0.55 |
| Morning stiffness duration >45 min‡ | 92 (77) | 68 (43) | <0.001 | 33 (69) | 0.25 | 10 (20) | <0.001 |
| Morning stiffness, min, median (IQR) | 120 (60, 240) | 30 (5, 120) | <0.001 | 60 (30, 180) | 0.11 | 10 (0,30) | <0.001 |
| Weight loss of >2 kg | 45 (36) | 40 (24) | 0.021 | 16 (33) | 0.68 | 4 (8) | <0.001 |
| Shoulder pain or limited range of motion | 121 (97) | 158 (93) | 0.20 | 47 (96) | 0.77 | 49 (94) | 0.42 |
| Hip pain or limited range of motion | 71 (57) | 59 (35) | <0.001 | 15 (31) | 0.002 | 12 (23) | <0.001 |
| Shoulder tenderness | 96 (77) | 126 (75) | 0.66 | 40 (82) | 0.49 | 34 (65) | 0.12 |
| Hip tenderness | 59 (47) | 47 (28) | 0.001 | 12 (24) | 0.006 | 9 (17) | <0.001 |
| Carpal tunnel syndrome | 19 (15) | 27 (16) | 0.90 | 11 (22) | 0.28 | 8 (15) | 0.99 |
| Peripheral synovitis (distal swelling, tenosynovitis or arthritis)‡ | 48 (39) | 78 (46) | 0.20 | 41 (84) | <0.001 | 11 (21) | 0.024 |
| Other joint pain‡ | 63 (51) | 109 (66) | 0.011 | 40 (85) | <0.001 | 29 (57) | 0.50 |
| Abnormal CRP and/or ESR‡ | 116 (96) | 99 (63) | <0.001 | 41 (85) | 0.017 | 18 (41) | <0.001 |
| Presence of RF and/or ACPA‡ | 11 (10) | 37 (25) | 0.004 | 19 (41) | <0.001 | 5 (12) | 0.79 |
| Abnormal serum protein electrophoresis‡ | 43 (52) | 32 (35) | 0.027 | 9 (36) | 0.17 | 9 (35) | 0.13 |
| MHAQ, mean±SD | 1.2±0.6 | 0.8±0.6 | <0.001 | 1.1±0.7 | 0.32 | 0.5±0.6 | <0.001 |
↵* Values are number (percentage) unless specified. Percentages for laboratory results are the number of abnormal tests results divided by the number of patients tested.
ACPA, anticitrullinated protein antibody; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; MHAQ, modified health assessment questionnaire; PMR, polymyalgia rheumatica; RF, rheumatoid factor.
↵† Bilateral rotator cuff syndrome and/or adhesive capsulitis, rotator cuff tear, glenohumeral osteoarthritis.
↵‡ Data not available on all subject.