Minimal clinically important improvement (MCII) score of absolute change in patients with knee or hip OA, by low, intermediate, and high baseline score tertiles
| Knee OA | Hip OA | |||||
|---|---|---|---|---|---|---|
| Baseline score tertile | Baseline score tertile | |||||
| Low | Intermediate | High | Low | Intermediate | High | |
| Results are shown as mean (95% confidence interval) {tertile}. | ||||||
| The MCII was defined as the 75th centile of the change in score among patients whose evaluation of response to treatment was “good”, for three patient reported outcomes: pain, as assessed on a visual analogue scale (VAS); global assessment of disease status, on a VAS; or the Western Ontario McMaster Universities Osteoarthritis Index (WOMAC) function subscale score. | ||||||
| Pain (0–100 mm VAS) | −10.8 | −27.4 | −36.6 | −7.2 | −23.9 | −29.7 |
| (−12.7 to −8.7) | (−29.7 to −24.6) | (−38.3 to −34.7) | (−10.7 to −2.9) | (−28.3 to −18.0) | (−35.4 to −21.8) | |
| {30 to 51.0} | {51.1 to 66.2} | {>66.2} | {30 to 49.3} | {49.4 to 65.4} | {>65.4} | |
| Patient’s global assessment of disease (0–100 mm VAS) | −6.4 | −24.6 | −43.2 | −4.3 | −26.0 | −29.9 |
| (−8.6 to −3.8) | (−26.8 to −22.1) | (−46.8 to −38.7) | (−6.9 to −1.4) | (−28.3 to −23.3) | (−34.5 to −24.3) | |
| {⩽50.4} | {50.5 to 68.7} | {>68.7} | {⩽49.9} | {50.0 to 69.9} | {>69.9} | |
| WOMAC function score (0–100) | −5.3 | −11.8 | −20.4 | −2.6 | −14.8 | −15.1 |
| (−6.5 to −3.8) | (−13.0 to −10.4) | (−22.5 to −18.1) | (−4.4 to −0.5) | (−17.0 to −12.0) | (−18.9 to −10.0) | |
| {⩽35.3} | {35.4 to 51.5} | {>51.5} | {⩽38.2} | {38.3 to 52.9} | {>52.9} | |