Footnotes

• Handling editor Josef S Smolen

• Twitter @RakibaBelkhir

• Contributors Substantial contributions to the conception or design of the work; or the acquisition, analysis or interpretation of data for the work: MP, GN, RB, JH, SP, RS, XM and SB. Drafting the work or revising it critically for important intellectual content: MP, GN, RB, JH, SP, RS, XM and SB. Final approval of the version to be published: MP, GN, RB, JH, SP, RS, XM and SB. Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved: MP and SB.

• Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

• Competing interests XM: honorarium from Astra-Zeneca, BMS, Galapagos, GSK, Novartis, Pfizer.

• Patient and public involvement Patients and/or the public were not involved in the design, or conduct, or reporting, or dissemination plans of this research.

• Provenance and peer review Not commissioned; externally peer reviewed.