A 25-year-old man was admitted to our hospital because of life-threatening haemoptoe and haematemesis. Recurring painful oral and genital aphtae and an episode of epididymitis led to a diagnosis of Behçet’s disease 18 months earlier.¹ Treatment with colchicine (1 mg/day) and prednisone (50 mg/day) was started, with a rapid tapering of prednisone. Intermittent fever and a cardiac murmur led to the suspicion of endocarditis 6 months later. Transoesophageal echocardiography disclosed a right ventricular cardiac thrombus of 4 cm diameter. The clinical investigation did not show signs of vasculitis nor could a thrombophilia be diagnosed. Oral anticoagulation was initiated and continued until complete resolution of the cardiac thrombus. Azathioprine (75 mg/day) was prescribed in combination with prednisone (75 mg/day), with the recommendation to …