Demographics of the three clinical validation datasets and their number of BA pairs assessed by the automatic BA analysis
Status | CF-control dataset | Longitudinal datasets | ||||||
Manual BA (n=23) | Automatic BA (n=23) | Copenhagen (n=57) | Ataluren (n=197) | |||||
CF | Control | CF | Control | CF | CF | |||
Time points | Baseline | Follow-up | Baseline | Follow-up | ||||
Age (years)—median (IQR) | 11 (9.5–12.3) | 13.9 (8.7–15) | 11 (9.5–12.3) | 13.9 (8.7–15) | 12.6 (9.1–15.1) | 13.9 (11.1–17) | 21 (15–26) | 22 (16–26) |
Male—n (%) | 6 (55) | 7 (58) | 6 (55) | 7 (58) | 28 (50) | 28 (51) | 80 (48) | 89 (49) |
CT scans analysed (n) | 11 | 12 | 11 | 12 | 56 | 55 | 167 | 180 |
Total BA pairs measured (n) | 3290 | 1563 | 3259 | 1443 | 12 798 | 14 648 | 54 840 | 65 673 |
BA (n) pairs per CT scan—mean (SD) | 299 (104) | 130 (37) | 296 (167) | 120 (34) | 229 (106) | 266 (122) | 328 (161) | 365 (162) |
%, percentage; BA pairs, bronchus-artery pairs; CF, cystic fibrosis; (n), number.