Table 1

Demographics of the three clinical validation datasets and their number of BA pairs assessed by the automatic BA analysis

StatusCF-control datasetLongitudinal datasets
Manual BA
(n=23)
Automatic BA
(n=23)
Copenhagen
(n=57)
Ataluren
(n=197)
CFControlCFControlCFCF
Time pointsBaselineFollow-upBaselineFollow-up
Age (years)—median (IQR)11
(9.5–12.3)
13.9
(8.7–15)
11
(9.5–12.3)
13.9
(8.7–15)
12.6
(9.1–15.1)
13.9
(11.1–17)
21
(15–26)
22
(16–26)
Male—n (%)6 (55)7 (58)6 (55)7 (58)28 (50)28 (51)80 (48)89 (49)
CT scans analysed (n)111211125655167180
Total BA pairs measured (n)329015633259144312 79814 64854 84065 673
BA (n) pairs per CT scan—mean (SD)299 (104)130 (37)296 (167)120 (34)229 (106)266 (122)328 (161)365 (162)
  • %, percentage; BA pairs, bronchus-artery pairs; CF, cystic fibrosis; (n), number.